Precise gene editing preserves hematopoietic stem cell function following transient p53-mediated DNA damage response G Schiroli, A Conti, S Ferrari, L Della Volpe, A Jacob, L Albano, S Beretta, ... Cell Stem Cell 24 (4), 551-565. e8, 2019 | 257 | 2019 |
An early‐senescence state in aged mesenchymal stromal cells contributes to hematopoietic stem and progenitor cell clonogenic impairment through the activation of a pro … D Gnani, S Crippa, L Della Volpe, V Rossella, A Conti, E Lettera, S Rivis, ... Aging cell 18 (3), e12933, 2019 | 135 | 2019 |
Identification of RNA polymerase III-transcribed genes in eukaryotic genomes G Dieci, A Conti, A Pagano, D Carnevali Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1829 (3-4 …, 2013 | 99 | 2013 |
Identification of RNA polymerase III-transcribed Alu loci by computational screening of RNA-Seq data A Conti, D Carnevali, V Bollati, S Fustinoni, M Pellegrini, G Dieci Nucleic acids research 43 (2), 817-835, 2015 | 68 | 2015 |
Choice of template delivery mitigates the genotoxic risk and adverse impact of editing in human hematopoietic stem cells S Ferrari, A Jacob, D Cesana, M Laugel, S Beretta, A Varesi, G Unali, ... Cell Stem Cell 29 (10), 1428-1444. e9, 2022 | 51 | 2022 |
p53 activation: a checkpoint for precision genome editing? A Conti, R Di Micco Genome Medicine 10, 1-4, 2018 | 24 | 2018 |
Epigenetic and transcriptional modifications in repetitive elements in petrol station workers exposed to benzene and MTBE F Rota, A Conti, L Campo, C Favero, L Cantone, V Motta, E Polledri, ... International journal of environmental research and public health 15 (4), 735, 2018 | 24 | 2018 |
Genetic engineering meets hematopoietic stem cell biology for next-generation gene therapy S Ferrari, E Valeri, A Conti, S Scala, A Aprile, R Di Micco, ... Cell Stem Cell 30 (5), 549-570, 2023 | 20 | 2023 |
Oncogene-induced senescence in hematopoietic progenitors features myeloid restricted hematopoiesis, chronic inflammation and histiocytosis R Biavasco, E Lettera, K Giannetti, D Gilioli, S Beretta, A Conti, S Scala, ... Nature Communications 12 (1), 4559, 2021 | 20 | 2021 |
Premature senescence and increased oxidative stress in the thymus of down syndrome patients GE Marcovecchio, F Ferrua, E Fontana, S Beretta, M Genua, I Bortolomai, ... Frontiers in Immunology 12, 669893, 2021 | 20 | 2021 |
Whole-genome expression analysis of mammalian-wide interspersed repeat elements in human cell lines D Carnevali, A Conti, M Pellegrini, G Dieci Dna Research 24 (1), 59-69, 2017 | 20 | 2017 |
Hydroquinone induces DNA hypomethylation-independent overexpression of retroelements in human leukemia and hematopoietic stem cells A Conti, F Rota, E Ragni, C Favero, V Motta, L Lazzari, V Bollati, ... Biochemical and Biophysical Research Communications 474 (4), 691-695, 2016 | 18 | 2016 |
Follicular helper T cell signature of replicative exhaustion, apoptosis, and senescence in common variable immunodeficiency G Milardi, B Di Lorenzo, J Gerosa, F Barzaghi, G Di Matteo, M Omrani, ... European Journal of Immunology 52 (7), 1171-1189, 2022 | 14 | 2022 |
Alu RNA modulates the expression of cell cycle genes in human fibroblasts S Cantarella, D Carnevali, M Morselli, A Conti, M Pellegrini, B Montanini, ... International journal of molecular sciences 20 (13), 3315, 2019 | 13 | 2019 |
Mesenchymal stromal cells improve the transplantation outcome of CRISPR-Cas9 gene-edited human HSPCs S Crippa, A Conti, V Vavassori, S Ferrari, S Beretta, S Rivis, R Bosotti, ... Molecular Therapy 31 (1), 230-248, 2023 | 11 | 2023 |
Therapy-induced senescence upregulates antigen presentation machinery and triggers anti-tumor immunity in Acute Myeloid Leukemia D Gilioli, S Fusco, T Tavella, K Giannetti, A Conti, A Santoro, E Carsana, ... bioRxiv, 2022.11. 17.515658, 2022 | 4 | 2022 |
The Murine PSE/TATA-dependent transcriptome: evidence of functional homologies with its human counterpart MJ Bruzzone, P Gavazzo, S Massone, C Balbi, F Villa, A Conti, G Dieci, ... International journal of molecular sciences 13 (11), 14813-14827, 2012 | 4 | 2012 |
S255: CELLULAR SENESCENCE AND INFLAMMATORY PROGRAMS ARE UNINTENDED CONSEQUENCES OF CRISPR-CAS9 GENE EDITING IN HEMATOPOIETIC STEM AND PROGENITOR CELLS A Conti, T Tavella, R De Marco, F Midena, S Ferrari, S Beretta, C Brombin, ... HemaSphere 7 (S3), e7928137, 2023 | | 2023 |
P1327: INHIBITING TELOMERIC DNA DAMAGE RESPONSE AS A NEW THERAPEUTIC STRATEGY TO REJUVENATE THE AGEING HEMATOPOIETIC SYSTEM A Oppezzo, S Sepe, F Rossiello, A Conti, E Marinelli, S Boggio, ADI Lillo, ... HemaSphere 7 (S3), e6000984, 2023 | | 2023 |
P429: THERAPY-INDUCED SENESCENCE TRIGGERS UPREGULATION OF ANTIGEN PRESENTATION VIA PRC2 INHIBITION AND PROMOTES ANTI-TUMOUR IMMUNITY IN ACUTE MYELOID LEUKAEMIA D Gilioli, S Fusco, T Tavella, K Giannetti, A Conti, S Antonella, E Carsana, ... HemaSphere 7 (S3), e5505132, 2023 | | 2023 |