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Roberto El-Khoury
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Recent progress in non-native nucleic acid modifications
LK McKenzie, R El-Khoury, JD Thorpe, MJ Damha, M Hollenstein
Chemical Society Reviews 50 (8), 5126-5164, 2021
1752021
[C–H⋯ anion] interactions mediate the templation and anion binding properties of topologically non-trivial metal–organic structures in aqueous solutions
RA Bilbeisi, T Prakasam, M Lusi, R El Khoury, C Platas-Iglesias, ...
Chemical Science 7 (4), 2524-2531, 2016
522016
A mechanism for the extension and unfolding of parallel telomeric G-quadruplexes by human telomerase at single-molecule resolution
BP Paudel, AL Moye, H Abou Assi, R El-Khoury, SB Cohen, JK Holien, ...
Elife 9, e56428, 2020
512020
2′-Fluoro-arabinonucleic acid (FANA): a versatile tool for probing biomolecular interactions
R El-Khoury, MJ Damha
Accounts of Chemical Research 54 (9), 2287-2297, 2021
362021
2′-Fluoroarabinonucleic acid modification traps G-quadruplex and i-motif structures in human telomeric DNA
H Abou Assi, R El-Khoury, C González, MJ Damha
Nucleic Acids Research 45 (20), 11535-11546, 2017
352017
Topological transformation of a trefoil knot into a [2] catenane
T Prakasam, RA Bilbeisi, R El-Khoury, LJ Charbonnière, M Elhabiri, ...
Dalton Transactions 46 (47), 16474-16479, 2017
62017
i-Motif folding intermediates with zero-nucleotide loops are trapped by 2′-fluoroarabinocytidine via F··· H and O··· H hydrogen bonds
R El-Khoury, V Macaluso, C Hennecker, AK Mittermaier, M Orozco, ...
Communications chemistry 6 (1), 31, 2023
52023
Nucleoside Analogues with a seven-membered sugar ring: synthesis and structural compatibility in DNA–RNA hybrids
SK Jana, S Harikrishna, S Sudhakar, R El-Khoury, PI Pradeepkumar, ...
The Journal of Organic Chemistry 87 (5), 2367-2379, 2022
52022
End-ligation can dramatically stabilize i-motifs at neutral pH
R El-Khoury, MJ Damha
Chemical Communications 59 (25), 3715-3718, 2023
42023
DNA i-motif levels are overwhelmingly depleted in living human cells: insights from in-cell NMR.
L Trantirek, P Viskova, E Istvankova, J Rynes, S Dzatko, T Loja, ...
12023
Telomeric i-motifs and C-strands inhibit parallel G-quadruplex extension by telomerase
R El-Khoury, M Roman, HA Assi, AL Moye, TM Bryan, MJ Damha
Nucleic Acids Research 51 (19), 10395-10410, 2023
12023
DNA i-motif levels are overwhelmingly depleted in living human cells: insights from in-cell NMR.
P Viskova, E Istvankova, J Rynes, S Dzatko, T Loja, M Lenarcic Zivkovic, ...
bioRxiv, 2023.10. 01.558881, 2023
12023
In-cell NMR suggests that DNA i-motif levels are strongly depleted in living human cells
P Víšková, E Ištvánková, J Ryneš, Š Džatko, T Loja, ML Živković, R Rigo, ...
Nature communications 15 (1), 1992, 2024
2024
The Effects of FANA Modifications on Non-canonical Nucleic Acid Structures
R El-Khoury, M Garavís, MJ Damha
Handbook of Chemical Biology of Nucleic Acids, 1-37, 2023
2023
i-Motif folding intermediates with zero-nucleotide loops are trapped by 2'-fluoroarabinocytidine via F center dot center dot center dot H and O center dot center dot center dot …
R El-Khoury, V Macaluso, C Hennecker, AK Mittermaier, M Orozco, ...
COMMUNICATIONS CHEMISTRY 6 (1), 2023
2023
Applications of 19F NMR Techniques with Artificial Nucleic Acid.
C Cabrero Fernández, R El-Khoury, M Garavís, MJ Damha, C González
2021
Stabilizing i-motif DNA through chemical modification and end-ligation-towards biochemical applications.
R El-Khoury, M Garavís, C González, MJ Damha
2020
Fluorinated therapeutic agents to combat ALS.
M Garavís, R El-Khoury, CM Santiveri, R Campos-Olivas, MJ Damha, ...
2020
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