Nuclear FAK controls chemokine transcription, Tregs, and evasion of anti-tumor immunity A Serrels, T Lund, B Serrels, A Byron, RC McPherson, A von Kriegsheim, ... Cell 163 (1), 160-173, 2015 | 382 | 2015 |
Deconstruction of a metastatic tumor microenvironment reveals a common matrix response in human cancers OMT Pearce, RM Delaine-Smith, E Maniati, S Nichols, J Wang, S Böhm, ... Cancer discovery 8 (3), 304-319, 2018 | 274 | 2018 |
Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits Pparγ expression and promotes pancreatic cancer progression in mice E Maniati, M Bossard, N Cook, JB Candido, N Emami-Shahri, ... The Journal of clinical investigation 121 (12), 4685-4699, 2011 | 266 | 2011 |
A strong B-cell response is part of the immune landscape in human high-grade serous ovarian metastases A Montfort, O Pearce, E Maniati, BG Vincent, L Bixby, S Böhm, T Dowe, ... Clinical Cancer Research 23 (1), 250-262, 2017 | 181 | 2017 |
Up for Mischief? IL-17/Th17 in the tumour microenvironment E Maniati, R Soper, T Hagemann Oncogene 29 (42), 5653-5662, 2010 | 168 | 2010 |
Macrophage scavenger receptor a promotes tumor progression in murine models of ovarian and pancreatic cancer C Neyen, A Plüddemann, S Mukhopadhyay, E Maniati, M Bossard, ... The Journal of Immunology 190 (7), 3798-3805, 2013 | 127 | 2013 |
Basement membrane stiffness determines metastases formation R Reuten, S Zendehroud, M Nicolau, L Fleischhauer, A Laitala, ... Nature materials 20 (6), 892-903, 2021 | 106 | 2021 |
Reduced expression of histone methyltransferases KMT2C and KMT2D correlates with improved outcome in pancreatic ductal adenocarcinoma JBN Dawkins, J Wang, E Maniati, JA Heward, L Koniali, HM Kocher, ... Cancer research 76 (16), 4861-4871, 2016 | 90 | 2016 |
A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer C Berlato, MN Khan, T Schioppa, R Thompson, E Maniati, A Montfort, ... The Journal of clinical investigation 127 (3), 801-813, 2017 | 89 | 2017 |
Control of apoptosis in autoimmunity E Maniati, P Potter, NJ Rogers, BJ Morley The Journal of Pathology: A Journal of the Pathological Society of Great …, 2008 | 80 | 2008 |
TGFBI production by macrophages contributes to an immunosuppressive microenvironment in ovarian cancer LSM Lecker, C Berlato, E Maniati, R Delaine-Smith, OMT Pearce, O Heath, ... Cancer research 81 (22), 5706-5719, 2021 | 75 | 2021 |
Discrepancies in the tumor microenvironment of spontaneous and orthotopic murine models of pancreatic cancer uncover a new immunostimulatory phenotype for B cells S Spear, JB Candido, JR McDermott, C Ghirelli, E Maniati, SA Beers, ... Frontiers in immunology 10, 542, 2019 | 73 | 2019 |
Mouse ovarian cancer models recapitulate the human tumor microenvironment and patient response to treatment E Maniati, C Berlato, G Gopinathan, O Heath, P Kotantaki, A Lakhani, ... Cell reports 30 (2), 525-540. e7, 2020 | 71 | 2020 |
A defect in Marco expression contributes to systemic lupus erythematosus development via failure to clear apoptotic cells NJ Rogers, MJ Lees, L Gabriel, E Maniati, SJ Rose, PK Potter, BJ Morley The Journal of Immunology 182 (4), 1982-1990, 2009 | 68 | 2009 |
A vaccinia virus armed with interleukin-10 is a promising therapeutic agent for treatment of murine pancreatic cancer LS Chard, E Maniati, P Wang, Z Zhang, D Gao, J Wang, F Cao, J Ahmed, ... Clinical cancer research 21 (2), 405-416, 2015 | 67 | 2015 |
Deconstruction of a metastatic tumor microenvironment reveals a common matrix response in human cancers. Cancer Discov. 2018; 8: 304–319. doi: 10.1158/2159-8290 OMT Pearce, RM Delaine-Smith, E Maniati, S Nichols, J Wang, S Böhm, ... CD-17-0284.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 50 | |
Specific mechanisms of chromosomal instability indicate therapeutic sensitivities in high-grade serous ovarian carcinoma N Tamura, N Shaikh, D Muliaditan, TN Soliman, JR McGuinness, ... Cancer research 80 (22), 4946-4959, 2020 | 39 | 2020 |
IL-17 mediates resistance to anti-VEGF therapy E Maniati, T Hagemann Nature medicine 19 (9), 1092-1094, 2013 | 39 | 2013 |
Chemotherapy induces tumor-associated macrophages that aid adaptive immune responses in ovarian cancer O Heath, C Berlato, E Maniati, A Lakhani, C Pegrum, P Kotantaki, ... Cancer immunology research 9 (6), 665-681, 2021 | 37 | 2021 |
A human multi-cellular model shows how platelets drive production of diseased extracellular matrix and tissue invasion B Malacrida, S Nichols, E Maniati, R Jones, R Delanie-Smith, ... Iscience 24 (6), 2021 | 25 | 2021 |