| Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy CC Liu, T Kanekiyo, H Xu, G Bu Nature Reviews Neurology 9 (2), 106-118, 2013 | 2187 | 2013 |
| Intraneuronal Aβ42 accumulation in human brain GK Gouras, J Tsai, J Naslund, B Vincent, M Edgar, F Checler, ... The American journal of pathology 156 (1), 15-20, 2000 | 1123 | 2000 |
| APP processing in Alzheimer's disease Y Zhang, R Thompson, H Zhang, H Xu Molecular brain 4 (1), 1-13, 2011 | 733 | 2011 |
| Intraneuronal Alzheimer Aβ42 accumulates in multivesicular bodies and is associated with synaptic pathology RH Takahashi, TA Milner, F Li, EE Nam, MA Edgar, H Yamaguchi, ... The American journal of pathology 161 (5), 1869-1879, 2002 | 726 | 2002 |
| Estrogen reduces neuronal generation of Alzheimer β-amyloid peptides H Xu, GK Gouras, JP Greenfield, B Vincent, J Naslund, L Mazzarelli, ... Nature medicine 4 (4), 447-451, 1998 | 618 | 1998 |
| Stimulation of β-amyloid precursor protein trafficking by insulin reduces intraneuronal β-amyloid and requires mitogen-activated protein kinase signaling L Gasparini, GK Gouras, R Wang, RS Gross, MF Beal, P Greengard, H Xu Journal of Neuroscience 21 (8), 2561-2570, 2001 | 557 | 2001 |
| Chaperones increase association of tau protein with microtubules F Dou, WJ Netzer, K Tanemura, F Li, FU Hartl, A Takashima, GK Gouras, ... Proceedings of the National Academy of Sciences 100 (2), 721-726, 2003 | 488 | 2003 |
| Association of γ-secretase with lipid rafts in post-Golgi and endosome membranes KS Vetrivel, H Cheng, W Lin, T Sakurai, T Li, N Nukina, PC Wong, H Xu, ... Journal of Biological Chemistry 279 (43), 44945-44954, 2004 | 482 | 2004 |
| Inhibition of amyloid-β aggregation and caspase-3 activation by the Ginkgo biloba extract EGb761 Y Luo, JV Smith, V Paramasivam, A Burdick, KJ Curry, JP Buford, I Khan, ... Proceedings of the national academy of sciences 99 (19), 12197-12202, 2002 | 456 | 2002 |
| Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer β-amyloid peptides JP Greenfield, J Tsai, GK Gouras, B Hai, G Thinakaran, F Checler, ... Proceedings of the National Academy of Sciences 96 (2), 742-747, 1999 | 447 | 1999 |
| ApoE and Aβ in Alzheimer’s disease: accidental encounters or partners? T Kanekiyo, H Xu, G Bu Neuron 81 (4), 740-754, 2014 | 434 | 2014 |
| Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription Y Chen, K Zhou, R Wang, Y Liu, YD Kwak, T Ma, RC Thompson, Y Zhao, ... Proceedings of the National Academy of Sciences 106 (10), 3907-3912, 2009 | 398 | 2009 |
| Hypoxia-inducible factor 1α (HIF-1α)-mediated hypoxia increases BACE1 expression and β-amyloid generation X Zhang, K Zhou, R Wang, J Cui, SA Lipton, FF Liao, H Xu, Y Zhang Journal of Biological Chemistry 282 (15), 10873-10880, 2007 | 382 | 2007 |
| Does insulin dysfunction play a role in Alzheimer's disease? L Gasparini, WJ Netzer, P Greengard, H Xu Trends in pharmacological sciences 23 (6), 288-293, 2002 | 381 | 2002 |
| Oligomeric Aβ-induced synaptic dysfunction in Alzheimer’s disease S Tu, S Okamoto, SA Lipton, H Xu Molecular neurodegeneration 9 (1), 1-12, 2014 | 380 | 2014 |
| Testosterone reduces neuronal secretion of Alzheimer's β-amyloid peptides GK Gouras, H Xu, RS Gross, JP Greenfield, B Hai, R Wang, P Greengard Proceedings of the national academy of sciences 97 (3), 1202-1205, 2000 | 375 | 2000 |
| Generation of Alzheimer β-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation H Xu, D Sweeney, R Wang, G Thinakaran, ACY Lo, SS Sisodia, ... Proceedings of the National Academy of Sciences 94 (8), 3748-3752, 1997 | 348 | 1997 |
| Proteolytic processing of Alzheimer’s β‐amyloid precursor protein H Zhang, Q Ma, Y Zhang, H Xu Journal of Neurochemistry: REVIEW 120, 9-21, 2012 | 328 | 2012 |
| Potential roles of insulin and IGF-1 in Alzheimer's disease L Gasparini, H Xu Trends in neurosciences 26 (8), 404-406, 2003 | 321 | 2003 |
| PEN-2 and APH-1 coordinately regulate proteolytic processing of presenilin 1 W Luo, H Wang, H Li, BS Kim, S Shah, HJ Lee, G Thinakaran, TW Kim, ... Journal of Biological Chemistry 278 (10), 7850-7854, 2003 | 312 | 2003 |
Guojun BuProfessor of Neuroscience, Mayo ClinicVerified email at mayo.edu
