| Studies on the metabolism of troglitazone to reactive intermediates in vitro and in vivo. Evidence for novel biotransformation pathways involving quinone methide formation and … K Kassahun, PG Pearson, W Tang, I McIntosh, K Leung, C Elmore, ... Chemical research in toxicology 14 (1), 62-70, 2001 | 361 | 2001 |
| Use of radiolabeled compounds in drug metabolism and pharmacokinetic studies EM Isin, CS Elmore, GN Nilsson, RA Thompson, L Weidolf Chemical research in toxicology 25 (3), 532-542, 2012 | 254 | 2012 |
| Metabolism and excretion of the dipeptidyl peptidase 4 inhibitor [14C] sitagliptin in humans SH Vincent, JR Reed, AJ Bergman, CS Elmore, B Zhu, S Xu, D Ebel, ... Drug metabolism and disposition 35 (4), 533-538, 2007 | 240 | 2007 |
| Isotope chemistry; a useful tool in the drug discovery arsenal CS Elmore, RA Bragg Bioorganic & medicinal chemistry letters 25 (2), 167-171, 2015 | 200 | 2015 |
| Apolipoprotein E binding drives structural and compositional rearrangement of mRNA-containing lipid nanoparticles F Sebastiani, M Yanez Arteta, M Lerche, L Porcar, C Lang, RA Bragg, ... ACS nano 15 (4), 6709-6722, 2021 | 153 | 2021 |
| The use of isotopically labeled compounds in drug discovery CS Elmore Annual Reports in Medicinal Chemistry 44, 515-534, 2009 | 82 | 2009 |
| Disposition of the dipeptidyl peptidase 4 inhibitor sitagliptin in rats and dogs MG Beconi, JR Reed, Y Teffera, YQ Xia, CJ Kochansky, DQ Liu, S Xu, ... Drug Metabolism and Disposition 35 (4), 525-532, 2007 | 76 | 2007 |
| 14Carbon monoxide made simple – novel approach to the generation, utilization, and scrubbing of 14carbon monoxide AT Lindhardt, R Simonssen, RH Taaning, TM Gøgsig, GN Nilsson, ... Journal of Labelled Compounds and Radiopharmaceuticals 55 (11), 411-418, 2012 | 61 | 2012 |
| Multiple compound-related adverse properties contribute to liver injury caused by endothelin receptor antagonists JG Kenna, SH Stahl, JA Eakins, AJ Foster, LC Andersson, J Bergare, ... Journal of Pharmacology and Experimental Therapeutics 352 (2), 281-290, 2015 | 49 | 2015 |
| Transition‐metal‐free carbon isotope exchange of phenyl acetic acids G Destro, K Horkka, O Loreau, DA Buisson, L Kingston, A Del Vecchio, ... Angewandte Chemie 132 (32), 13592-13597, 2020 | 48 | 2020 |
| Development of a PET radioligand for the central 5-HT1B receptor: radiosynthesis and characterization in cynomolgus monkeys of eight radiolabeled compounds JD Andersson, ME Pierson, SJ Finnema, B Gulyás, R Heys, CS Elmore, ... Nuclear medicine and biology 38 (2), 261-272, 2011 | 37 | 2011 |
| Photochemical Strategy for Carbon Isotope Exchange with CO2 V Babin, A Talbot, A Labiche, G Destro, A Del Vecchio, CS Elmore, ... ACS Catalysis 11 (5), 2968-2976, 2021 | 36 | 2021 |
| 2, 6-Disubstituted pyrazines and related analogs as NR2B site antagonists of the NMDA receptor with anti-depressant activity DG Brown, DL Maier, MA Sylvester, TN Hoerter, E Menhaji-Klotz, ... Bioorganic & medicinal chemistry letters 21 (11), 3399-3403, 2011 | 36 | 2011 |
| PET tracers to study clinically relevant hepatic transporters A Testa, M Zanda, CS Elmore, P Sharma Molecular Pharmaceutics 12 (7), 2203-2216, 2015 | 35 | 2015 |
| An integrated strategy for in vivo metabolite profiling using high-resolution mass spectrometry based data processing techniques J Guo, M Zhang, CS Elmore, K Vishwanathan Analytica Chimica Acta 780, 55-64, 2013 | 33 | 2013 |
| Bioactivation of 2, 3-diaminopyridine-containing bradykinin B1 receptor antagonists: irreversible binding to liver microsomal proteins and formation of glutathione conjugates C Tang, R Subramanian, Y Kuo, S Krymgold, P Lu, SD Kuduk, C Ng, ... Chemical research in toxicology 18 (6), 934-945, 2005 | 33 | 2005 |
| New trends and applications in carboxylation for isotope chemistry RA Bragg, M Sardana, M Artelsmair, CS Elmore Journal of Labelled Compounds and Radiopharmaceuticals 61 (13), 934-948, 2018 | 32 | 2018 |
| Deuterated active pharmaceutical ingredients: A science‐based proposal for synthesis, analysis, and control. Part 1: Framing the problem B Czeskis, CS Elmore, A Haight, D Hesk, BD Maxwell, SA Miller, ... Journal of Labelled Compounds and Radiopharmaceuticals 62 (11), 690-694, 2019 | 31 | 2019 |
| Use of Dibutyl[14C]formamide as a Formylating Reagent in the Vilsmeier–Haack Reaction and Synthesis of a 14C‐Labeled Novel Phosphodiesterase‐4 (PDE‐4 … JZ Ho, CS Elmore, MA Wallace, D Yao, MP Braun, DC Dean, DG Melillo, ... Helvetica chimica acta 88 (5), 1040-1047, 2005 | 30 | 2005 |
| [N-methyl-3H3] AZ10419369 binding to the 5-HT1B receptor: in vitro characterization and in vivo receptor occupancy DL Maier, C Sobotka-Briner, M Ding, ME Powell, Q Jiang, G Hill, JR Heys, ... Journal of Pharmacology and Experimental Therapeutics 330 (1), 342-351, 2009 | 29 | 2009 |
