| Botulinum neurotoxins: biology, pharmacology, and toxicology M Pirazzini, O Rossetto, R Eleopra, C Montecucco Pharmacological reviews 69 (2), 200-235, 2017 | 668 | 2017 |
| Botulinum neurotoxins: genetic, structural and mechanistic insights O Rossetto, M Pirazzini, C Montecucco Nature Reviews Microbiology 12 (8), 535-549, 2014 | 627 | 2014 |
| Historical perspectives and guidelines for botulinum neurotoxin subtype nomenclature MW Peck, TJ Smith, F Anniballi, JW Austin, L Bano, M Bradshaw, ... Toxins 9 (1), 38, 2017 | 269 | 2017 |
| Thioredoxin and its reductase are present on synaptic vesicles, and their inhibition prevents the paralysis induced by botulinum neurotoxins M Pirazzini, G Zanetti, A Megighian, M Scorzeto, S Fillo, CC Shone, T Binz, ... Cell reports 8 (6), 1870-1878, 2014 | 116 | 2014 |
| On the translocation of botulinum and tetanus neurotoxins across the membrane of acidic intracellular compartments M Pirazzini, O Leka, G Zanetti, O Rossetto, C Montecucco Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (3), 467-474, 2016 | 106 | 2016 |
| Double anchorage to the membrane and intact inter‐chain disulfide bond are required for the low pH induced entry of tetanus and botulinum neurotoxins into neurons M Pirazzini, O Rossetto, P Bolognese, CC Shone, C Montecucco Cellular microbiology 13 (11), 1731-1743, 2011 | 81 | 2011 |
| Botulinum neurotoxin type A is internalized and translocated from small synaptic vesicles at the neuromuscular junction C Colasante, O Rossetto, L Morbiato, M Pirazzini, J Molgó, C Montecucco Molecular Neurobiology 48, 120-127, 2013 | 79 | 2013 |
| The thioredoxin reductase-thioredoxin system is involved in the entry of tetanus and botulinum neurotoxins in the cytosol of nerve terminals M Pirazzini, F Bordin, O Rossetto, CC Shone, T Binz, C Montecucco FEBS letters 587 (2), 150-155, 2013 | 72 | 2013 |
| Novel botulinum neurotoxins: Exploring underneath the iceberg tip DA Tehran, M Pirazzini Toxins 10 (5), 190, 2018 | 68 | 2018 |
| Skeletal muscle mTORC1 regulates neuromuscular junction stability M Baraldo, A Geremia, M Pirazzini, L Nogara, F Solagna, C Türk, H Nolte, ... Journal of Cachexia, Sarcopenia and Muscle 11 (1), 208-225, 2020 | 54 | 2020 |
| CXCL 12α/SDF‐1 from perisynaptic Schwann cells promotes regeneration of injured motor axon terminals S Negro, F Lessi, E Duregotti, P Aretini, M La Ferla, S Franceschi, ... EMBO molecular medicine 9 (8), 1000-1010, 2017 | 53 | 2017 |
| Botulinum neurotoxin serotype D is poorly effective in humans: an in vivo electrophysiological study R Eleopra, C Montecucco, G Devigili, C Lettieri, S Rinaldo, L Verriello, ... Clinical Neurophysiology 124 (5), 999-1004, 2013 | 53 | 2013 |
| Botulinum neurotoxins: mechanism of action O Rossetto, M Pirazzini, F Fabris, C Montecucco Botulinum Toxin Therapy, 35-47, 2021 | 52 | 2021 |
| Neutralisation of specific surface carboxylates speeds up translocation of botulinum neurotoxin type B enzymatic domain M Pirazzini, T Henke, O Rossetto, S Mahrhold, N Krez, A Rummel, ... FEBS letters 587 (23), 3831-3836, 2013 | 49 | 2013 |
| Challenges in searching for therapeutics against Botulinum Neurotoxins M Pirazzini, O Rossetto Expert opinion on drug discovery 12 (5), 497-510, 2017 | 46 | 2017 |
| Hsp90 is involved in the entry of clostridial neurotoxins into the cytosol of nerve terminals D Azarnia Tehran, M Pirazzini, O Leka, A Mattarei, F Lista, T Binz, ... Cellular Microbiology 19 (2), e12647, 2017 | 46 | 2017 |
| Re-assembled botulinum neurotoxin inhibits CNS functions without systemic toxicity E Ferrari, ES Maywood, L Restani, M Caleo, M Pirazzini, O Rossetto, ... Toxins 3 (4), 345-355, 2011 | 45 | 2011 |
| The thioredoxin reductase–Thioredoxin redox system cleaves the interchain disulphide bond of botulinum neurotoxins on the cytosolic surface of synaptic vesicles M Pirazzini, G Zanetti, F Lista, T Binz, CC Shone, O Rossetto, ... Toxicon 107, 32-36, 2015 | 44 | 2015 |
| Postnatal development and distribution of sympathetic innervation in mouse skeletal muscle T Straka, V Vita, K Prokshi, SJ Hörner, MM Khan, M Pirazzini, ... International journal of molecular sciences 19 (7), 1935, 2018 | 42 | 2018 |
| Diphtheria toxin conformational switching at acidic pH O Leka, F Vallese, M Pirazzini, P Berto, C Montecucco, G Zanotti The FEBS journal 281 (9), 2115-2122, 2014 | 40 | 2014 |
Ornella RossettoRicercatore universitario Università di PadovaVerified email at unipd.it
