Molecular dissection of telomeric repeat-containing RNA biogenesis unveils the presence of distinct and multiple regulatory pathways A Porro, S Feuerhahn, P Reichenbach, J Lingner Molecular and cellular biology 30 (20), 4808-4817, 2010 | 279 | 2010 |
Functional characterization of the TERRA transcriptome at damaged telomeres A Porro, S Feuerhahn, J Delafontaine, H Riethman, J Rougemont, ... Nature Communications 5, 2014 | 267 | 2014 |
TERRA biogenesis, turnover and implications for function S Feuerhahn, N Iglesias, A Panza, A Porro, J Lingner FEBS letters 584 (17), 3812-3818, 2010 | 205 | 2010 |
In vivo transcriptional regulation of N-Myc target genes is controlled by E-box methylation G Perini, D Diolaiti, A Porro, G Della Valle Proceedings of the National Academy of Sciences of the United States of …, 2005 | 172 | 2005 |
ABCC multidrug transporters in childhood neuroblastoma: clinical and biological effects independent of cytotoxic drug efflux MJ Henderson, M Haber, A Porro, MA Munoz, N Iraci, C Xue, J Murray, ... Journal of the National Cancer Institute 103 (16), 1236-1251, 2011 | 151 | 2011 |
Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis T Liu, AEL Tee, A Porro, SA Smith, T Dwarte, PY Liu, N Iraci, E Sekyere, ... Proceedings of the National Academy of Sciences 104 (47), 18682-18687, 2007 | 145 | 2007 |
TERRA-Reinforced Association of LSD1 with MRE11 Promotes Processing of Uncapped Telomeres A Porro, S Feuerhahn, J Lingner Cell Reports, 2014 | 142 | 2014 |
Direct and coordinate regulation of ATP-binding cassette transporter genes by Myc factors generates specific transcription signatures that significantly affect the … A Porro, M Haber, D Diolaiti, N Iraci, M Henderson, S Gherardi, E Valli, ... Journal of Biological Chemistry 285 (25), 19532-19543, 2010 | 119 | 2010 |
Fork cleavage-religation cycle and active transcription mediate replication restart after fork stalling at co-Transcriptional R-loops N Chappidi, Z Nascakova, B Boleslavska, R Zellweger, E Isik, M Andrs, ... Molecular Cell 77 (3), 528-541. e8, 2020 | 117 | 2020 |
A SP1/MIZ1/MYCN repression complex recruits HDAC1 at the TRKA and p75NTR promoters and affects neuroblastoma malignancy by inhibiting the cell response to NGF N Iraci, D Diolaiti, A Papa, A Porro, E Valli, S Gherardi, S Herold, M Eilers, ... Cancer research 71 (2), 404-412, 2011 | 110 | 2011 |
CtIP-Mediated Fork Protection Synergizes with BRCA1 to Suppress Genomic Instability upon DNA Replication Stress S Przetocka, A Porro, HA Bolck, C Walker, A Lezaja, A Trenner, ... Molecular Cell, 2018 | 106 | 2018 |
Cullin3-KLHL15 ubiquitin ligase mediates CtIP protein turnover to fine-tune DNA-end resection LP Ferretti, SF Himmels, A Trenner, C Walker, C von Aesch, ... Nature Communications 7, 2016 | 70 | 2016 |
c-MYC oncoprotein dictates transcriptional profiles of ATP-binding cassette transporter genes in chronic myelogenous leukemia CD34+ hematopoietic progenitor cells A Porro, N Iraci, S Soverini, D Diolaiti, S Gherardi, C Terragna, S Durante, ... Molecular Cancer Research 9 (8), 1054-1066, 2011 | 58 | 2011 |
Functional cooperation between TrkA and p75< sup> NTR</sup> accelerates neuronal differentiation by increased transcription of GAP-43 and p21 (CIP/WAF) genes via ERK1/2 and AP … D Diolaiti, R Bernardoni, S Trazzi, A Papa, A Porro, F Bono, JM Herbert, ... Experimental cell research 313 (14), 2980-2992, 2007 | 53 | 2007 |
No DDRama at chromosome ends: TRF2 takes centre stage S Feuerhahn, L Chen, B Luke, A Porro Trends in biochemical sciences, 2015 | 52 | 2015 |
FAN1 interaction with ubiquitylated PCNA alleviates replication stress and preserves genomic integrity independently of BRCA2 A Porro, M Berti, J Pizzolato, S Bologna, S Kaden, A Saxer, Y Ma, ... Nature Communications 8, 2017 | 50 | 2017 |
FAN1, a DNA repair nuclease, as a modifier of repeat expansion disorders AL Deshmukh, A Porro, M Mohiuddin, S Lanni, GB Panigrahi, MC Caron, ... Journal of Huntington's Disease 10 (1), 95-122, 2021 | 36 | 2021 |
A Single‐Stranded DNA‐Encoded Chemical Library Based on a Stereoisomeric Scaffold Enables Ligand Discovery by Modular Assembly of Building Blocks G Bassi, N Favalli, M Vuk, M Catalano, A Martinelli, A Trenner, A Porro, ... Advanced Science 7 (22), 2001970, 2020 | 36 | 2020 |
FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington’s disease R Goold, J Hamilton, T Menneteau, M Flower, EL Bunting, SG Aldous, ... Cell Reports 36 (9), 109649, 2021 | 34 | 2021 |
FAN1-MLH1 interaction affects repair of DNA interstrand cross-links and slipped-CAG/CTG repeats A Porro, M Mohiuddin, C Zurfluh, V Spegg, J Dai, F Iehl, V Ropars, ... Science Advances 7 (31), eabf7906, 2021 | 20 | 2021 |