| IL-11 is a crucial determinant of cardiovascular fibrosis S Schafer Nature 552 (7683), 110-115, 2017 | 518 | 2017 |
| PDGFRα+ pericryptal stromal cells are the critical source of Wnts and RSPO3 for murine intestinal stem cells in vivo G Greicius, Z Kabiri, K Sigmundsson, C Liang, R Bunte, ... PNAS 115 (14), E3172-E3181, 2018 | 276 | 2018 |
| Adipocyte Ceramides Regulate Subcutaneous Adipose Browning, Inflammation, and Metabolism B Chaurasia Cell Metabolism 24, 1-15, 2016 | 218 | 2016 |
| Nephrin promotes cell-cell adhesion through homophilic interactions J Khoshnoodi, K Sigmundsson, LG Öfverstedt, U Skoglund, B Öbrink, ... The American journal of pathology 163 (6), 2337-2346, 2003 | 183 | 2003 |
| The structure of p53 tumour suppressor protein reveals the basis for its functional plasticity AL Okorokov, MB Sherman, C Plisson, V Grinkevich, K Sigmundsson, ... The EMBO Journal 25 (21), 5191-5200, 2006 | 149 | 2006 |
| Carcinoembryonic antigen-related cell adhesion molecule 1 expression and signaling in human, mouse, and rat leukocytes: evidence for replacement of the short cytoplasmic domain … BB Singer, I Scheffrahn, R Heymann, K Sigmundsson, R Kammerer, ... The Journal of Immunology 168 (10), 5139-5146, 2002 | 136 | 2002 |
| RETRACTED: Vulnerability of glioblastoma cells to catastrophic vacuolization and death induced by a small molecule SS Kitambi, EM Toledo, D Usoskin, S Wee, A Harisankar, R Svensson, ... Cell 157 (2), 313-328, 2014 | 117 | 2014 |
| Determination of active concentrations and association and dissociation rate constants of interacting biomolecules: an analytical solution to the theory for kinetic and mass … K Sigmundsson, G Másson, R Rice, N Beauchemin, B Öbrink Biochemistry 41 (26), 8263-8276, 2002 | 113 | 2002 |
| Proinsulin C-peptide elicits disaggregation of insulin resulting in enhanced physiological insulin effects J Shafqat, E Melles, K Sigmundsson, BL Johansson, K Ekberg, G Alvelius, ... Cellular and Molecular Life Sciences 63, 1805-1811, 2006 | 92 | 2006 |
| Cellular internalization of proinsulin C-peptide E Lindahl, U Nyman, E Melles, K Sigmundsson, M Ståhlberg, J Wahren, ... Cellular and molecular life sciences 64, 479-486, 2007 | 73 | 2007 |
| The CEACAM1 N-terminal Ig domain mediates cis-and trans-binding and is essential for allosteric rearrangements of CEACAM1 microclusters E Klaile, O Vorontsova, K Sigmundsson, MM Müller, BB Singer, ... Journal of cell biology 187 (4), 553-567, 2009 | 71 | 2009 |
| Mechanism of chain selection in the assembly of collagen IV: A prominent role for the α2 chain J Khoshnoodi, K Sigmundsson, JP Cartailler, O Bondar, ... Journal of biological chemistry 281 (9), 6058-6069, 2006 | 67 | 2006 |
| Cross talk in HEK293 cells between Nrf2, HIF, and NF-κB activities upon challenges with redox therapeutics characterized with single-cell resolution K Johansson, M Cebula, O Rengby, K Dreij, KE Carlström, ... Antioxidants & redox signaling 26 (6), 229-246, 2017 | 48 | 2017 |
| Control of density-dependent, cell state-specific signal transduction by the cell adhesion molecule CEACAM1, and its influence on cell cycle regulation I Scheffrahn, BB Singer, K Sigmundsson, L Lucka, B Öbrink Experimental Cell Research 307 (2), 427-435, 2005 | 48 | 2005 |
| Discovery of the first potent and selective inhibitors of human dCTP pyrophosphatase 1 S Llona-Minguez, A Hoglund, SA Jacques, L Johansson, ... Journal of medicinal chemistry 59 (3), 1140-1148, 2016 | 45 | 2016 |
| Computational Analysis of Isoform‐Specific Signal Regulation by CEACAM1—A Cell Adhesion Molecule Expressed in PC12 Cells B Öbrink, H Sawa, I Scheffrahn, BB Singer, K Sigmundsson, U Sundberg, ... Annals of the New York Academy of Sciences 971 (1), 597-607, 2002 | 41 | 2002 |
| Culturing functional pancreatic islets on α5-laminins and curative transplantation to diabetic mice K Sigmundsson, JRM Ojala, MK Öhman, et al. Matrix Biology, 15, 2018 | 33 | 2018 |
| Orthogonal genome-wide screens of bat cells identify MTHFD1 as a target of broad antiviral therapy DE Anderson, J Cui, Q Ye, B Huang, Y Tan, C Jiang, W Zu, J Gong, W Liu, ... Proceedings of the National Academy of Sciences 118 (39), e2104759118, 2021 | 32 | 2021 |
| Immunomodulatory activity of commonly used drugs on Fc-receptor-mediated human natural killer cell activation J Theorell, AL Gustavsson, B Tesi, K Sigmundsson, HG Ljunggren, ... Cancer Immunology, Immunotherapy 63, 627-641, 2014 | 32 | 2014 |
| Inhibition of Insulin‐Regulated Aminopeptidase (IRAP) by Arylsulfonamides SR Borhade, U Rosenström, J Sävmarker, T Lundbäck, ... ChemistryOpen 3 (6), 256-263, 2014 | 29 | 2014 |
Karl TryggvasonProfessor, Karolinska Institute, Stockholm & Duke-NUS, Singaporetryggvason.com üzerinde doğrulanmış e-posta adresine sahip
