Azo amino acids derivatives D Lauffer, M Mullican US Patent 6,528,533, 2003 | 180* | 2003 |
Inhibitors of interleukin-1β converting enzyme GW Bemis, JMC Golec, DJ Lauffer, MD Mullican, MA Murcko, ... US Patent 5,656,627, 1997 | 156* | 1997 |
Inhibitors of interleukin-1β converting enzyme GW Bemis, JMC Golec, DJ Lauffer, MD Mullican, MA Murcko, ... US Patent 5,847,135, 1998 | 136 | 1998 |
Inhibitors of interleukin-1β converting enzyme GW Bemis, JMC Golec, DJ Lauffer, MD Mullican, MA Murcko US Patent 5,756,466, 1998 | 133 | 1998 |
Inhibitors of interleukin-1β converting enzyme GW Bemis, JMC Golec, DJ Lauffer, MD Mullican, MA Murcko, ... US Patent 5,716,929, 1998 | 121* | 1998 |
Inhibitors of interleukin-1β converting enzyme GW Bemis, JMC Golec, DJ Lauffer, MD Mullican, MA Murcko, ... US Patent 5,716,929, 1998 | 119* | 1998 |
Inhibitors of interleukin-1β converting enzyme MJ Batchelor, D Bebbington, GW Bemis, WH Fridman, RJ Gillespie, ... US Patent 5,874,424, 1999 | 114 | 1999 |
Inhibitors of interleukin-1β converting enzyme GW Bemis, JMC Golec, DJ Lauffer, MD Mullican, MA Murcko, ... US Patent 5,716,929, 1998 | 100 | 1998 |
Inhibitors of interleukin-1β converting enzyme JMC Golec, DJ Lauffer, DJ Livingston, MD Mullican, PL Nyce, ... US Patent 6,350,741, 2002 | 96 | 2002 |
Inhibitors of interleukin-1β converting enzyme GW Bemis, JMC Golec, DJ Lauffer, MD Mullican, MA Murcko, ... US Patent 5,716,929, 1998 | 93 | 1998 |
Compositions useful as inhibitors of GSK-3 J Cao, D Choquette, R Davies, C Forster, D Lauffer, A Pierce, ... US Patent App. 10/125,885, 2003 | 92 | 2003 |
Compositions useful as inhibitors of protein kinases A Aronov, DJ Lauffer, P Li, RC Tomlinson US Patent 7,446,199, 2008 | 76 | 2008 |
3-Aryl-4-(arylhydrazono)-1H-pyrazol-5-ones: Highly ligand efficient and potent inhibitors of GSK3β M Arnost, A Pierce, E ter Haar, D Lauffer, J Madden, K Tanner, J Green Bioorganic & medicinal chemistry letters 20 (5), 1661-1664, 2010 | 74 | 2010 |
Inhibitors of interleukin-1β Converting enzyme inhibitors MJ Batchelor, D Bebbington, GW Bemis, WH Fridman, RJ Gillespie, ... US Patent 6,204,261, 2001 | 71* | 2001 |
Inhibitors of interleukin-1β converting enzyme GW Bemis, JMC Golec, DJ Lauffer, MD Mullican, MA Murcko, ... US Patent 5,973,111, 1999 | 71 | 1999 |
Second-generation antibacterial benzimidazole ureas: discovery of a preclinical candidate with reduced metabolic liability AL Grillot, AL Tiran, D Shannon, E Krueger, Y Liao, H O’Dowd, Q Tang, ... Journal of Medicinal Chemistry 57 (21), 8792-8816, 2014 | 70 | 2014 |
c-MET protein kinase inhibitors DJ Lauffer, RJ Davies, D Stamos, A Aronov, DD Deininger, R Grey Jr, ... US Patent 7,872,031, 2011 | 70 | 2011 |
A practical synthesis of (S) 3-tert-butoxycarbonylamino-2-oxo-2, 3, 4, 5-tetrahydro-1, 5-benzodiazepine-1-acetic acid methyl ester as a conformationally restricted dipeptido … DJ Lauffer, MD Mullican Bioorganic & medicinal chemistry letters 12 (8), 1225-1227, 2002 | 64 | 2002 |
Azaindoles useful as inhibitors of JAK and other protein kinases F Salituro, L Farmer, R Bethiel, E Harrington, J Green, J Come, D Lauffer, ... US Patent 7,507,826, 2009 | 57 | 2009 |
Inhibitors of interleukin-1β converting enzyme GW Bemis, JMC Golec, DJ Lauffer, MD Mullican, MA Murcko, ... US Patent 6,420,522, 2002 | 56 | 2002 |