Li-Fan Lu
Li-Fan Lu
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Regulatory T cells: mechanisms of differentiation and function
SZ Josefowicz, LF Lu, AY Rudensky
Annual review of immunology 30, 531-564, 2012
Cutting edge: contact-mediated suppression by CD4+ CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism
DC Gondek, LF Lu, SA Quezada, S Sakaguchi, RJ Noelle
The journal of immunology 174 (4), 1783-1786, 2005
Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein
LF Lu, TH Thai, DP Calado, A Chaudhry, M Kubo, K Tanaka, GB Loeb, ...
Immunity 30 (1), 80-91, 2009
Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses
LF Lu, MP Boldin, A Chaudhry, LL Lin, KD Taganov, T Hanada, ...
Cell 142 (6), 914-929, 2010
Mast cells are essential intermediaries in regulatory T-cell tolerance
LF Lu, EF Lind, DC Gondek, KA Bennett, MW Gleeson, K Pino-Lagos, ...
Nature 442 (7106), 997-1002, 2006
Dicer-dependent microRNA pathway safeguards regulatory T cell function
A Liston, LF Lu, D O'Carroll, A Tarakhovsky, AY Rudensky
The Journal of experimental medicine 205 (9), 1993-2004, 2008
VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses
L Wang, R Rubinstein, JL Lines, A Wasiuk, C Ahonen, Y Guo, LF Lu, ...
Journal of Experimental Medicine 208 (3), 577-592, 2011
MicroRNA in the immune system, microRNA as an immune system
LF Lu, A Liston
Immunology 127 (3), 291-298, 2009
In Vivo Target Gene Activation via CRISPR/Cas9-Mediated Trans-epigenetic Modulation
HK Liao, F Hatanaka, T Araoka, P Reddy, MZ Wu, Y Sui, T Yamauchi, ...
Cell 171 (7), 1495-1507. e15, 2017
Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3+ regulatory T cells
W Pierson, B Cauwe, A Policheni, SM Schlenner, D Franckaert, J Berges, ...
Nature immunology 14 (9), 959, 2013
A single miRNA-mRNA interaction affects the immune response in a context-and cell-type-specific manner
LF Lu, G Gasteiger, IS Yu, A Chaudhry, JP Hsin, Y Lu, PD Bos, LL Lin, ...
Immunity 43 (1), 52-64, 2015
Inhibition of miR-146a prevents enterovirus-induced death by restoring the production of type I interferon
BC Ho, IS Yu, LF Lu, A Rudensky, HY Chen, CW Tsai, YL Chang, CT Wu, ...
Nature communications 5 (1), 1-12, 2014
An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses
M Mann, A Mehta, JL Zhao, K Lee, GK Marinov, Y Garcia-Flores, LF Lu, ...
Nature communications 8 (1), 1-13, 2017
Molecular orchestration of differentiation and function of regulatory T cells
LF Lu, A Rudensky
Genes & development 23 (11), 1270-1282, 2009
Transplantation survival is maintained by granzyme B+ regulatory cells and adaptive regulatory T cells
DC Gondek, V DeVries, EC Nowak, LF Lu, KA Bennett, ZA Scott, ...
The Journal of Immunology 181 (7), 4752-4760, 2008
miR-23∼ 27∼ 24 clusters control effector T cell differentiation and function
S Cho, CJ Wu, T Yasuda, LO Cruz, AA Khan, LL Lin, DT Nguyen, M Miller, ...
Journal of Experimental Medicine 213 (2), 235-249, 2016
Progress and challenge of microRNA research in immunity
HM Lee, DT Nguyen, LF Lu
Frontiers in genetics 5, 178, 2014
Id2 and Id3 maintain the regulatory T cell pool to suppress inflammatory disease
M Miyazaki, K Miyazaki, S Chen, M Itoi, M Miller, LF Lu, N Varki, ...
Nature immunology 15 (8), 767-776, 2014
MicroRNA in the adaptive immune system, in sickness and in health
A Liston, M Linterman, LF Lu
Journal of clinical immunology 30 (3), 339-346, 2010
PD-L1: CD80 cis-heterodimer triggers the co-stimulatory receptor CD28 while repressing the inhibitory PD-1 and CTLA-4 pathways
Y Zhao, CK Lee, CH Lin, RB Gassen, X Xu, Z Huang, C Xiao, C Bonorino, ...
Immunity 51 (6), 1059-1073. e9, 2019
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