Edward Kastenhuber
Edward Kastenhuber
Weill Cornell Medical College
Verified email at med.cornell.edu
Cited by
Cited by
Putting p53 in context
ER Kastenhuber, SW Lowe
Cell 170 (6), 1062-1078, 2017
Inducible in vivo genome editing with CRISPR-Cas9
LE Dow, J Fisher, KP O'rourke, A Muley, ER Kastenhuber, G Livshits, ...
Nature biotechnology 33 (4), 390-394, 2015
Whole exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma
K Kannan, A Inagaki, J Silber, D Gorovets, J Zhang, ER Kastenhuber, ...
Oncotarget 3 (10), 1194, 2012
Dicer-regulated microRNAs 222 and 339 promote resistance of cancer cells to cytotoxic T-lymphocytes by down-regulation of ICAM-1
R Ueda, G Kohanbash, K Sasaki, M Fujita, X Zhu, ER Kastenhuber, ...
Proceedings of the National Academy of Sciences 106 (26), 10746-10751, 2009
Immunotherapeutic approaches for glioma
H Okada, G Kohanbash, X Zhu, ER Kastenhuber, A Hoji, R Ueda, M Fujita
Critical Reviews™ in Immunology 29 (1), 2009
Disruption of CRAF-mediated MEK activation is required for effective MEK inhibition in KRAS mutant tumors
P Lito, A Saborowski, J Yue, M Solomon, E Joseph, S Gadal, ...
Cancer cell 25 (5), 697-710, 2014
p53-dependent Nestin regulation links tumor suppression to cellular plasticity in liver cancer
DF Tschaharganeh, W Xue, DF Calvisi, M Evert, TV Michurina, LE Dow, ...
Cell 158 (3), 579-592, 2014
IDH mutation and neuroglial developmental features define clinically distinct subclasses of lower grade diffuse astrocytic glioma
D Gorovets, K Kannan, R Shen, ER Kastenhuber, N Islamdoust, ...
Clinical Cancer Research 18 (9), 2490-2501, 2012
Deletions linked to TP53 loss drive cancer through p53-independent mechanisms
Y Liu, C Chen, Z Xu, C Scuoppo, CD Rillahan, J Gao, B Spitzer, ...
Nature 531 (7595), 471-475, 2016
Optimized base editors enable efficient editing in cells, organoids and mice
MP Zafra, EM Schatoff, A Katti, M Foronda, M Breinig, AY Schweitzer, ...
Nature biotechnology 36 (9), 888-893, 2018
Systemic inhibition of transforming growth factor-β in glioma-bearing mice improves the therapeutic efficacy of glioma-associated antigen peptide vaccines
R Ueda, M Fujita, X Zhu, K Sasaki, ER Kastenhuber, G Kohanbash, ...
Clinical Cancer Research 15 (21), 6551-6559, 2009
18F-fluorodeoxy-glucose positron emission tomography marks MYC-overexpressing human basal-like breast cancers
N Palaskas, SM Larson, N Schultz, E Komisopoulou, J Wong, D Rohle, ...
Cancer research 71 (15), 5164-5174, 2011
Effective immunotherapy against murine gliomas using type 1 polarizing dendritic cells—significant roles of CXCL10
M Fujita, X Zhu, R Ueda, K Sasaki, G Kohanbash, ER Kastenhuber, ...
Cancer research 69 (4), 1587-1595, 2009
Genomic dissection of the epidermal growth factor receptor (EGFR)/PI3K pathway reveals frequent deletion of the EGFR phosphatase PTPRS in head and neck cancers
LGT Morris, BS Taylor, TG Bivona, Y Gong, S Eng, CW Brennan, ...
Proceedings of the National Academy of Sciences 108 (47), 19024-19029, 2011
Poly-ICLC promotes the infiltration of effector T cells into intracranial gliomas via induction of CXCL10 in IFN-α and IFN-γ dependent manners
X Zhu, BA Fallert-Junecko, M Fujita, R Ueda, G Kohanbash, ...
Cancer Immunology, Immunotherapy 59 (9), 1401-1409, 2010
Role of type 1 IFNs in antiglioma immunosurveillance—using mouse studies to guide examination of novel prognostic markers in humans
M Fujita, ME Scheurer, SA Decker, HA McDonald, G Kohanbash, ...
Clinical Cancer Research 16 (13), 3409-3419, 2010
p53 represses the mevalonate pathway to mediate tumor suppression
SH Moon, CH Huang, SL Houlihan, K Regunath, WA Freed-Pastor, ...
Cell 176 (3), 564-580. e19, 2019
DNAJB1–PRKACA fusion kinase interacts with β-catenin and the liver regenerative response to drive fibrolamellar hepatocellular carcinoma
ER Kastenhuber, G Lalazar, SL Houlihan, DF Tschaharganeh, T Baslan, ...
Proceedings of the National Academy of Sciences 114 (50), 13076-13084, 2017
Pten loss promotes MAPK pathway dependency in HER2/neu breast carcinomas
SH Ebbesen, M Scaltriti, CU Bialucha, N Morse, ER Kastenhuber, ...
Proceedings of the National Academy of Sciences 113 (11), 3030-3035, 2016
Quantitative assessment of intragenic receptor tyrosine kinase deletions in primary glioblastomas: their prevalence and molecular correlates
ER Kastenhuber, JT Huse, SH Berman, A Pedraza, J Zhang, Y Suehara, ...
Acta neuropathologica 127 (5), 747-759, 2014
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