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| Selective inhibition of tumor oncogenes by disruption of super-enhancers J Lovén, HA Hoke, CY Lin, A Lau, DA Orlando, CR Vakoc, JE Bradner, ... Cell 153 (2), 320-334, 2013 | 2799 | 2013 |
| RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia J Zuber, J Shi, E Wang, AR Rappaport, H Herrmann, EA Sison, D Magoon, ... Nature 478 (7370), 524-528, 2011 | 2096 | 2011 |
| Histone H3 lysine 9 methylation and HP1γ are associated with transcription elongation through mammalian chromatin CR Vakoc, SA Mandat, BA Olenchock, GA Blobel Molecular cell 19 (3), 381-391, 2005 | 910 | 2005 |
| Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control I Barbieri, K Tzelepis, L Pandolfini, J Shi, G Millán-Zambrano, SC Robson, ... Nature 552 (7683), 126-131, 2017 | 897 | 2017 |
| The mechanisms behind the therapeutic activity of BET bromodomain inhibition J Shi, CR Vakoc Molecular cell 54 (5), 728-736, 2014 | 864 | 2014 |
| Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data CM Rudin, JT Poirier, LA Byers, C Dive, A Dowlati, J George, JV Heymach, ... Nature Reviews Cancer 19 (5), 289-297, 2019 | 833 | 2019 |
| Organoid profiling identifies common responders to chemotherapy in pancreatic cancer H Tiriac, P Belleau, DD Engle, D Plenker, A Deschênes, TDD Somerville, ... Cancer discovery 8 (9), 1112-1129, 2018 | 780 | 2018 |
| Discovery of cancer drug targets by CRISPR-Cas9 screening of protein domains J Shi, E Wang, JP Milazzo, Z Wang, JB Kinney, CR Vakoc Nature biotechnology 33 (6), 661-667, 2015 | 762 | 2015 |
| Proximity among distant regulatory elements at the β-globin locus requires GATA-1 and FOG-1 CR Vakoc, DL Letting, N Gheldof, T Sawado, MA Bender, M Groudine, ... Molecular cell 17 (3), 453-462, 2005 | 625 | 2005 |
| DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells DJ Steger, MI Lefterova, L Ying, AJ Stonestrom, M Schupp, D Zhuo, ... Molecular and cellular biology 28 (8), 2825-2839, 2008 | 569 | 2008 |
| Global regulation of erythroid gene expression by transcription factor GATA-1 JJ Welch, JA Watts, CR Vakoc, Y Yao, H Wang, RC Hardison, GA Blobel, ... Blood 104 (10), 3136-3147, 2004 | 497 | 2004 |
| Transcriptional plasticity promotes primary and acquired resistance to BET inhibition P Rathert, M Roth, T Neumann, F Muerdter, JS Roe, M Muhar, S Deswal, ... Nature 525 (7570), 543-547, 2015 | 492 | 2015 |
| Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation J Shi, WA Whyte, CJ Zepeda-Mendoza, JP Milazzo, C Shen, JS Roe, ... Genes & development 27 (24), 2648-2662, 2013 | 472 | 2013 |
| Profile of histone lysine methylation across transcribed mammalian chromatin CR Vakoc, MM Sachdeva, H Wang, GA Blobel Molecular and cellular biology, 2006 | 458 | 2006 |
| Enhancer reprogramming promotes pancreatic cancer metastasis JS Roe, CI Hwang, TDD Somerville, JP Milazzo, EJ Lee, B Da Silva, ... Cell 170 (5), 875-888. e20, 2017 | 381 | 2017 |
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| FOG‐1 recruits the NuRD repressor complex to mediate transcriptional repression by GATA‐1 W Hong, M Nakazawa, YY Chen, R Kori, CR Vakoc, C Rakowski, ... The EMBO journal 24 (13), 2367-2378, 2005 | 341 | 2005 |
| BET bromodomain inhibition suppresses the function of hematopoietic transcription factors in acute myeloid leukemia JS Roe, F Mercan, K Rivera, DJ Pappin, CR Vakoc Molecular cell 58 (6), 1028-1039, 2015 | 338 | 2015 |
| MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia C Chen, Y Liu, AR Rappaport, T Kitzing, N Schultz, Z Zhao, AS Shroff, ... Cancer cell 25 (5), 652-665, 2014 | 337 | 2014 |
