Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens ME Dudley, JC Yang, R Sherry, MS Hughes, R Royal, U Kammula, ... Journal of Clinical Oncology 26 (32), 5233, 2008 | 1643 | 2008 |
Cutting edge: persistence of transferred lymphocyte clonotypes correlates with cancer regression in patients receiving cell transfer therapy PF Robbins, ME Dudley, J Wunderlich, M El-Gamil, YF Li, J Zhou, ... The Journal of Immunology 173 (12), 7125-7130, 2004 | 574 | 2004 |
Telomere length of transferred lymphocytes correlates with in vivo persistence and tumor regression in melanoma patients receiving cell transfer therapy J Zhou, X Shen, J Huang, RJ Hodes, SA Rosenberg, PF Robbins The Journal of Immunology 175 (10), 7046-7052, 2005 | 480 | 2005 |
Human effector CD8+ T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy CS Hinrichs, ZA Borman, L Gattinoni, Z Yu, WR Burns, J Huang, ... Blood, The Journal of the American Society of Hematology 117 (3), 808-814, 2011 | 365 | 2011 |
Rac1 inhibits TNF‐α‐induced endothelial cell apoptosis: dual regulation by reactive oxygen species SS Deshpande, P Angkeow, J Huang, M Ozaki, K Irani The FASEB Journal 14 (12), 1705-1714, 2000 | 306 | 2000 |
CXCR1-or CXCR2-modified CAR T cells co-opt IL-8 for maximal antitumor efficacy in solid tumors L Jin, H Tao, A Karachi, Y Long, AY Hou, M Na, KA Dyson, AJ Grippin, ... Nature communications 10 (1), 4016, 2019 | 257 | 2019 |
Survival, persistence, and progressive differentiation of adoptively transferred tumor-reactive T cells associated with tumor regression J Huang, HT Khong, ME Dudley, M El-Gamil, YF Li, SA Rosenberg, ... Journal of immunotherapy 28 (3), 258-267, 2005 | 241 | 2005 |
Modulation by IL-2 of CD70 and CD27 expression on CD8+ T cells: importance for the therapeutic effectiveness of cell transfer immunotherapy J Huang, KW Kerstann, M Ahmadzadeh, YF Li, M El-Gamil, ... The Journal of Immunology 176 (12), 7726-7735, 2006 | 197 | 2006 |
CD70, a novel target of CAR T-cell therapy for gliomas L Jin, H Ge, Y Long, C Yang, Y Chang, L Mu, EJ Sayour, G De Leon, ... Neuro-oncology 20 (1), 55-65, 2018 | 163 | 2018 |
T cells associated with tumor regression recognize frameshifted products of the CDKN2A tumor suppressor gene locus and a mutated HLA class I gene product J Huang, M El-Gamil, ME Dudley, YF Li, SA Rosenberg, PF Robbins The Journal of Immunology 172 (10), 6057-6064, 2004 | 142 | 2004 |
Infiltrative and drug‐resistant slow‐cycling cells support metabolic heterogeneity in glioblastoma LB Hoang‐Minh, FA Siebzehnrubl, C Yang, S Suzuki‐Hatano, K Dajac, ... The EMBO journal 37 (23), e98772, 2018 | 135 | 2018 |
Elevated serum soluble CD40 ligand in cancer patients may play an immunosuppressive role J Huang, C Jochems, T Talaie, A Anderson, A Jales, KY Tsang, ... Blood, The Journal of the American Society of Hematology 120 (15), 3030-3038, 2012 | 130 | 2012 |
Differential immune microenvironments and response to immune checkpoint blockade among molecular subtypes of murine medulloblastoma CD Pham, C Flores, C Yang, EM Pinheiro, JH Yearley, EJ Sayour, Y Pei, ... Clinical Cancer Research 22 (3), 582-595, 2016 | 107 | 2016 |
Regulation of p21 (WAF1) expression during normal myeloid differentiation RA Steinman, J Huang, B Yaroslavskiy, JP Goff, ED Ball, A Nguyen Blood, The Journal of the American Society of Hematology 91 (12), 4531-4542, 1998 | 101 | 1998 |
Dysregulation of glutamate transport enhances treg function that promotes VEGF blockade resistance in glioblastoma Y Long, H Tao, A Karachi, AJ Grippin, L Jin, Y Chang, W Zhang, ... Cancer research 80 (3), 499-509, 2020 | 86 | 2020 |
Soluble CD27-pool in humans may contribute to T cell activation and tumor immunity J Huang, C Jochems, AM Anderson, T Talaie, A Jales, RA Madan, ... The Journal of Immunology 190 (12), 6250-6258, 2013 | 81 | 2013 |
The IDH1 mutation-induced oncometabolite, 2-hydroxyglutarate, may affect DNA methylation and expression of PD-L1 in gliomas L Mu, Y Long, C Yang, L Jin, H Tao, H Ge, YE Chang, A Karachi, ... Frontiers in molecular neuroscience 11, 82, 2018 | 78 | 2018 |
Tumor associated CD70 expression is involved in promoting tumor migration and macrophage infiltration in GBM H Ge, L Mu, L Jin, C Yang, Y Chang, Y Long, G DeLeon, L Deleyrolle, ... International Journal of Cancer 141 (7), 1434-1444, 2017 | 78 | 2017 |
Modulation of temozolomide dose differentially affects T-cell response to immune checkpoint inhibition A Karachi, C Yang, F Dastmalchi, EJ Sayour, J Huang, H Azari, Y Long, ... Neuro-oncology 21 (6), 730-741, 2019 | 75 | 2019 |
Systemic activation of antigen-presenting cells via RNA-loaded nanoparticles EJ Sayour, G De Leon, C Pham, A Grippin, H Kemeny, J Chua, J Huang, ... Oncoimmunology 6 (1), e1256527, 2017 | 70 | 2017 |