Carbonic anhydrase inhibitors: Inhibition of the β-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates S Isik, F Kockar, M Aydin, O Arslan, OO Guler, A Innocenti, A Scozzafava, ... Bioorganic & medicinal chemistry 17 (3), 1158-1163, 2009 | 97 | 2009 |
IL-6 upregulates a disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAMTS-2) in human osteosarcoma cells mediated by JNK pathway M Alper, F Kockar Molecular and cellular biochemistry 393, 165-175, 2014 | 77 | 2014 |
Saccharomyces cerevisiae β-carbonic anhydrase: inhibition and activation studies S Isika, O Ozensoy Guler, F Kockar, M Aydin, O Arslan, C T Supuran Current pharmaceutical design 16 (29), 3327-3336, 2010 | 26 | 2010 |
Carbonic anhydrase activators: Activation of the β-carbonic anhydrase Nce103 from the yeast Saccharomyces cerevisiae with amines and amino acids S Isik, F Kockar, M Aydin, O Arslan, OO Guler, A Innocenti, A Scozzafava, ... Bioorganic & medicinal chemistry letters 19 (6), 1662-1665, 2009 | 25 | 2009 |
Induction of human ADAMTS-2 gene expression by IL-1α is mediated by a multiple crosstalk of MEK/JNK and PI3K pathways in osteoblast like cells M Alper, AT Aydemir, F Köçkar Gene 573 (2), 321-327, 2015 | 23 | 2015 |
Evaluation of in vitro effects of some analgesic drugs on erythrocyte and recombinant carbonic anhydrase I and II B Gökçe, N Gençer, O Arslan, SA Turkoğlu, M Alper, F Köçkar Journal of Enzyme Inhibition and Medicinal Chemistry 27 (1), 37-42, 2012 | 21 | 2012 |
SP1-mediated downregulation of ADAMTS3 gene expression in osteosarcoma models AT Aydemir, M Alper, F Kockar Gene 659, 1-10, 2018 | 20 | 2018 |
Mutation of Phe91 to Asn in human carbonic anhydrase I unexpectedly enhanced both catalytic activity and affinity for sulfonamide inhibitors F Kockar, A Maresca, M Aydın, S Işık, S Turkoglu, S Sinan, O Arslan, ... Bioorganic & medicinal chemistry 18 (15), 5498-5503, 2010 | 14 | 2010 |
Mutation of active site residues Asn67 to Ile, Gln92 to Val and Leu204 to Ser in human carbonic anhydrase II: Influences on the catalytic activity and affinity for inhibitors S Turkoglu, A Maresca, M Alper, F Kockar, S Işık, S Sinan, O Ozensoy, ... Bioorganic & medicinal chemistry 20 (7), 2208-2213, 2012 | 12 | 2012 |
Amplification of GC-rich ADAMTS-2 and URG4/URGCP promoter regions with optimized combination of PCR enhancers M Alper, E Tokay, F Köçkar Turkish Journal of Biology 40 (1), 196-205, 2016 | 6 | 2016 |
Molecular characterization of zeta class glutathione S-transferases from Pinus brutia Ten. E Oztetik, F Kockar, M Alper, M İscan Journal of genetics 94, 417-423, 2015 | 4 | 2015 |
İnsan ADAMTS2 geninin transkripsiyonel regülasyonu M Alper Balıkesir Üniversitesi Fen Bilimleri Enstitüsü, 2013 | 2 | 2013 |
Hypoxic regulation of ADAMTS-2 and-3 (a disintegrin and matrix metalloproteinase with thrombospondin motifs 2 and 3) procollagen N proteinases by HIF-1α in endothelial cells C Altuntaş, M Alper, Y Keleş, FN Sav, F Köçkar Molecular and Cellular Biochemistry 478 (5), 1151-1160, 2023 | 1 | 2023 |
USF1 suppresses expression of fibrillar type I, II, and III collagen and pNP adamts-3 in osteosarcoma cells M Alper, T Aydemir, F Köçkar Molecular Biology 55, 580-588, 2021 | 1 | 2021 |
Effect of angiogenesis related growth factors VEGF-a and FGF-1 on osteosarcoma cell proliferation M Alper Adıyaman University Journal of Science 10 (2), 403-412, 2020 | 1 | 2020 |
Sequence analysis of Tau class glutathione S-transferase from Pinus brutia (Pinaceae) E Öztetik, M Aydın, F Köçkar Wiley-Blackwell, 2008 | 1 | 2008 |
TGF-β1 transactivates ADAMTS-2 (ADAM Metallopeptidase With Thrombospondin Type 1 Motif 2) in Saos-2 Cells through canonical and non-canonical pathways M Alper Cytology and Genetics 57 (3), 282-289, 2023 | | 2023 |
Expression Pattern of ADAMTS-3 (A Disintegrin and Matrix Metalloproteinase Type, 1 Motif 3) in Normal and Cancer Cell Lines F Köçkar, M Alper, AT Aydemir Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi, 2022 | | 2022 |
Expression pattern of adamts-3 (A disintegrin and matrix metalloproteinase type, 1 motif 3) in normal and cancer cell lines M Alper, A tuğşen Aydemir, F Köçkar Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi 13 (1), 40-47, 2022 | | 2022 |
USF1 подавляет экспрессию генов, кодирующих фибриллярный коллаген типа I, II И III и pNP ADAMTS-3, в клетках остеосаркомы M Alper, T Aydemir, F Köçkar Молекулярная биология 55 (4), 634-642, 2021 | | 2021 |