Activation of mTOR/IκB-α/NF-κB pathway contributes to LPS-induced hypotension and inflammation in rats M Temiz-Resitoglu, SP Kucukkavruk, DS Guden, P Cecen, AN Sari, ... European Journal of Pharmacology 802, 7-19, 2017 | 74 | 2017 |
Inhibition of NLRP3 inflammasome prevents LPS-induced inflammatory hyperalgesia in mice: contribution of NF-κB, Caspase-1/11, ASC, NOX, and NOS isoforms A Dolunay, SP Senol, M Temiz-Resitoglu, DS Guden, AN Sari, ... Inflammation 40, 366-386, 2017 | 65 | 2017 |
Protection by mTOR inhibition on zymosan-induced systemic inflammatory response and oxidative/nitrosative stress: contribution of mTOR/MEK1/ERK1/2/IKKβ/IκB-α/NF-κB signalling … S Sahan-Firat, M Temiz-Resitoglu, DS Guden, SP Kucukkavruk, ... Inflammation 41, 276-298, 2018 | 31 | 2018 |
Pharmacological inhibition of soluble epoxide hydrolase attenuates chronic experimental autoimmune encephalomyelitis by modulating inflammatory and anti-inflammatory pathways … M Biliktu, SP Senol, M Temiz-Resitoglu, DS Guden, MF Horat, ... Inflammopharmacology 28, 1509-1524, 2020 | 25 | 2020 |
Eicosanoids derived from cytochrome P450 pathway of arachidonic acid and inflammatory shock B Tunctan, SP Senol, M Temiz-Resitoglu, DS Guden, S Sahan-Firat, ... Prostaglandins & Other Lipid Mediators 145, 106377, 2019 | 20 | 2019 |
Bexarotene, a selective RXRα agonist, reverses hypotension associated with inflammation and tissue injury in a rat model of septic shock B Tunctan, SP Kucukkavruk, M Temiz-Resitoglu, DS Guden, AN Sari, ... Inflammation 41, 337-355, 2018 | 19 | 2018 |
The role of Syk/IĸB‐α/NF‐ĸB pathway activation in the reversal effect of BAY 61‐3606, a selective Syk inhibitor, on hypotension and inflammation in a rat model of zymosan … D Unsal, M Kacan, M Temiz‐Resitoglu, DS Guden, B Korkmaz, AN Sari, ... Clinical and Experimental Pharmacology and Physiology 45 (2), 155-165, 2018 | 15 | 2018 |
NF‐κB activation mediates LPS‐or zymosan‐induced hypotension and inflammation reversed by BAY 61‐3606, a selective Syk inhibitor, in rat models of septic and non‐septic shock S Sahan‐Firat, M Temiz‐Resitoglu, DS Guden, SP Senol, AN Sari, M Cil, ... Clinical and Experimental Pharmacology and Physiology 46 (2), 173-182, 2019 | 13 | 2019 |
Pharmacological inhibition of mammalian target of rapamycin attenuates deoxycorticosterone acetate salt–induced hypertension and related pathophysiology: regulation of … M Temiz-Resitoglu, DS Guden, SP Senol, O Vezir, N Sucu, D Kibar, ... Journal of Cardiovascular Pharmacology 79 (3), 355-367, 2022 | 10 | 2022 |
Suppression of TLR4/MyD88/TAK1/NF-κB/COX-2 signaling pathway in the central nervous system by bexarotene, a selective RXR agonist, prevents hyperalgesia in the … SP Senol, M Temiz-Resitoglu, DS Guden, AN Sari, S Sahan-Firat, ... Neurochemical Research 46, 624-637, 2021 | 8 | 2021 |
Modulation of oxidative–nitrosative stress and inflammatory response by rapamycin in target and distant organs in rats exposed to hindlimb ischemia–reperfusion: the role of … Z Kocak, M Temiz-Resitoglu, DS Guden, O Vezir, N Sucu, S Balcı, ... Canadian Journal of Physiology and Pharmacology 97 (12), 1193-1203, 2019 | 8 | 2019 |
Inhibition of NLRP3 inflammasome contributes to protective effect of 5, 14-HEDGE against lipopolysaccharide-induced septic shock B Tunctan, SP Kucukkavruk, M Temiz-Resitoglu, DS Guden, AN Sari, ... International Journal of Pharmacology 13 (6), 654-666, 2017 | 7 | 2017 |
mTOR inhibition as a possible pharmacological target in the management of systemic inflammatory response and associated neuroinflammation by lipopolysaccharide challenge in rats DS Guden, M Temiz-Resitoglu, SP Senol, D Kibar, SN Yilmaz, B Tunctan, ... Canadian Journal of Physiology and Pharmacology 99 (9), 921-934, 2021 | 6 | 2021 |
Bexarotene Ameliorates LPS-Induced Hyperalgesia: Contribution of TLR4/MyD88-Dependent Pro-Inflammatory, Anti-Apoptotic and Anti-Inflammatory Signaling Pathways O Bahceli, SP Senol, M Temiz-Resitoglu, MF Horat, S Sahan-Firat, ... International Journal of Pharmacology 18 (6), 1171-1188, 2022 | 5 | 2022 |
Soluble epoxide hydrolase inhibitor trifluoromethoxyphenyl‐3‐(1‐propionylpiperidin‐4‐yl) urea prevents hyperalgesia through regulating NLRC4 inflammasome‐related pro … A Cagli, SP Senol, M Temiz‐Resitoglu, DS Guden, AN Sari, ... Drug Development Research 82 (6), 815-825, 2021 | 5 | 2021 |
Activation of GPR75 signaling pathway contributes to the effect of a 20-HETE mimetic, 5, 14-HEDGE, to prevent hypotensive and tachycardic responses to lipopolysaccharide in a … B Tunctan, SP Senol, M Temiz-Resitoglu, DE Yilmaz, DS Guden, ... Journal of Cardiovascular Pharmacology 80 (2), 276-293, 2022 | 4 | 2022 |
Contribution of mTOR to Oxidative/Nitrosative Stress via NADPH Oxidase System Activation in Zymosan-Induced Systemic Inflammation in Rats S Sahan-Firat, M Temiz-Resitoglu, DS Guden, SP Kucukkavruk, ... World Acad Sci Eng Technol Int J Med Health Sci 4 (5), 25, 2017 | 2 | 2017 |
NLRX1 ligand, docosahexaenoic acid, ameliorates LPS-induced inflammatory hyperalgesia by decreasing TRAF6/IKK/IkB-a/NF-kB signaling pathway activity DE Yilmaz, SP Senol, M Temiz-Resitoglu, S Sahan-Firat, B Tunctan Cellular and Molecular Biology 69 (9), 15-23, 2023 | 1 | 2023 |
Pyroptosis and necroptosis inhibitor necrosulfonamide prevents lipopolysaccharide-induced inflammatory hyperalgesia in mice B Ozgen, SP Senol, DE Yilmaz, M Temiz-Resitoglu, O Bahceli, B Tunctan | 1 | 2022 |
Targeting mTOR: up-to-date mTOR inhibitors. B Kilic, M Temiz-Resitoglu, S Sahan-Firat Bioorganic & Medicinal Chemistry Reports 2 (2), 2019 | 1 | 2019 |