Osvaldo Andrade Santos-Filho
Osvaldo Andrade Santos-Filho
Professor of Physical Chemistry and Molecular Modeling, Federal University of Rio de Janeiro
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Başlık
Alıntı yapanlar
Alıntı yapanlar
Yıl
Dietary flavonoids fisetin, luteolin and their derived compounds inhibit arginase, a central enzyme in Leishmania (Leishmania) amazonensis infection
LC Manjolin, MBG dos Reis, C do Carmo Maquiaveli, OA Santos-Filho, ...
Food chemistry 141 (3), 2253-2262, 2013
772013
Rational Design of New Antituberculosis Agents: Receptor-Independent Four-Dimensional Quantitative Structure− Activity Relationship Analysis of a Set of Isoniazid Derivatives
KFM Pasqualoto, EI Ferreira, OA Santos-Filho, AJ Hopfinger
Journal of medicinal chemistry 47 (15), 3755-3764, 2004
712004
Design, synthesis, and antiviral activity of new 1 H-1, 2, 3-triazole nucleoside ribavirin analogs
GF Maria de Lourdes, LCS Pinheiro, OA Santos-Filho, MDS Peçanha, ...
Medicinal Chemistry Research 23 (3), 1501-1511, 2014
692014
Mapping the Protein Interaction Network in Methicillin-Resistant Staphylococcus aureus
A Cherkasov, M Hsing, R Zoraghi, LJ Foster, RH See, N Stoynov, J Jiang, ...
Journal of proteome research 10 (3), 1139-1150, 2011
632011
Modelagem de proteínas por homologia
OA Santos Filho, RB Alencastro
Química Nova 26 (2), 253-259, 2003
622003
Molecular modeling of wild-type and antifolate resistant mutant Plasmodium falciparum DHFR
RT Delfino, OA Santos-Filho, JD Figueroa-Villar
Biophysical chemistry 98 (3), 287-300, 2002
622002
Inhibition of Leishmania (Leishmania) amazonensis and rat arginases by green tea EGCG,(+)-catechin and (−)-epicatechin: a comparative structural analysis of enzyme-inhibitor …
MBG dos Reis, LC Manjolin, C do Carmo Maquiaveli, OA Santos-Filho, ...
PLoS One 8 (11), e78387, 2013
562013
New trifluoromethyl triazolopyrimidines as anti-Plasmodium falciparum agents
N Boechat, L Pinheiro, TS Silva, ACC Aguiar, AS Carvalho, MM Bastos, ...
Molecules 17 (7), 8285-8302, 2012
562012
Type 2 antifolates in the chemotherapy of falciparum malaria
RT Delfino, OA Santos-Filho, JD Figueroa-Villar
Journal of the Brazilian Chemical Society 13 (6), 727-741, 2002
522002
A search for sources of drug resistance by the 4D-QSAR analysis of a set of antimalarial dihydrofolate reductase inhibitors
OA Santos-Filho, AJ Hopfinger
Journal of computer-aided molecular design 15 (1), 1-12, 2001
492001
Design and synthesis of new N-(5-trifluoromethyl)-1H-1, 2, 4-triazol-3-yl benzenesulfonamides as possible antimalarial prototypes
N Boechat, L Pinheiro, OA Santos-Filho, IC Silva
Molecules 16 (9), 8083-8097, 2011
462011
An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin
A Cherkasov, F Ban, O Santos-Filho, N Thorsteinson, M Fallahi, ...
Journal of medicinal chemistry 51 (7), 2047-2056, 2008
442008
Free energy force field (FEFF) 3D-QSAR analysis of a set of Plasmodium falciparum dihydrofolate reductase inhibitors
OA Santos-Filho, RK Mishra, AJ Hopfinger
Journal of computer-aided molecular design 15 (9), 787-810, 2001
412001
The receptor-dependent QSAR paradigm: an overview of the current state of the art
OA Santos-Filho, AJ Hopfinger, A Cherkasov, RB de Alencastro
Medicinal Chemistry 5 (4), 359-366, 2009
382009
Homology modeling of wild type and pyrimethamine/cycloguanil-cross resistant mutant type Plasmodium falciparum dihydrofolate reductase. A model for antimalarial chemotherapy …
OA Santos-Filho, RB de Alencastro, JD Figueroa-Villar
Biophysical chemistry 91 (3), 305-317, 2001
362001
Structure-based QSAR analysis of a set of 4-hydroxy-5, 6-dihydropyrones as inhibitors of HIV-1 protease: an application of the receptor-dependent (RD) 4D-QSAR formalism
OA Santos-Filho, AJ Hopfinger
Journal of chemical information and modeling 46 (1), 345-354, 2006
322006
In silico identification of anthropogenic chemicals as ligands of zebrafish sex hormone binding globulin
N Thorsteinson, F Ban, O Santos-Filho, SMH Tabaei, S Miguel-Queralt, ...
Toxicology and applied pharmacology 234 (1), 47-57, 2009
272009
The 4D‐QSAR Paradigm: Application to a Novel Set of Non‐peptidic HIV Protease Inhibitors
OA Santos‐Filho, AJ Hopfinger
Quantitative Structure‐Activity Relationships 21 (4), 369-381, 2002
272002
Molecular modeling of the interaction of trypanocide guanyl hydrazones with B-DNA
OA Santos-Filho, JD Figueroa-Villar, MT Araujo
Bioorganic & Medicinal Chemistry Letters 7 (13), 1797-1802, 1997
251997
A complete model of the Plasmodium falciparum bifunctional enzyme dihydrofolate reductase-thymidylate synthase: a model to design new antimalarials
TCC França, ALR de Medeiros, ECP dos Santos, OA Santos-Filho, ...
Journal of the Brazilian Chemical Society 15 (3), 450-454, 2004
232004
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