Binding of Sindbis virus to cell surface heparan sulfate AP Byrnes, DE Griffin Journal of Virology 72 (9), 7349-7356, 1998 | 354 | 1998 |
Adenovirus gene transfer causes inflammation in the brain AP Byrnes, JE Rusby, MJA Wood, HM Charlton Neuroscience 66 (4), 1015-1024, 1995 | 353 | 1995 |
Clearance of adenovirus by Kupffer cells is mediated by scavenger receptors, natural antibodies, and complement Z Xu, J Tian, JS Smith, AP Byrnes Journal of virology 82 (23), 11705-11713, 2008 | 213 | 2008 |
Immune responses to adenovirus vectors in the nervous system MJA Wood, HM Charlton, KJ Wood, K Kajiwara, AP Byrnes Trends in neurosciences 19 (11), 497-501, 1996 | 200 | 1996 |
Immunological instability of persistent adenovirus vectors in the brain: peripheral exposure to vector leads to renewed inflammation, reduced gene expression, and demyelination AP Byrnes, RE MacLaren, HM Charlton Journal of Neuroscience 16 (9), 3045-3055, 1996 | 190 | 1996 |
Coagulation factor X shields adenovirus type 5 from attack by natural antibodies and complement Z Xu, Q Qiu, J Tian, JS Smith, GM Conenello, T Morita, AP Byrnes Nature medicine 19 (4), 452-457, 2013 | 168 | 2013 |
Large-plaque mutants of Sindbis virus show reduced binding to heparan sulfate, heightened viremia, and slower clearance from the circulation AP Byrnes, DE Griffin Journal of virology 74 (2), 644-651, 2000 | 148 | 2000 |
Rapid Kupffer cell death after intravenous injection of adenovirus vectors E Manickan, JS Smith, J Tian, TL Eggerman, JN Lozier, J Muller, ... Molecular Therapy 13 (1), 108-117, 2006 | 147 | 2006 |
Inflammatory effects of gene transfer into the CNS with defective HSV-1 vectors. MJ Wood, AP Byrnes, DW Pfaff, SD Rabkin, HM Charlton Gene therapy 1 (5), 283-291, 1994 | 126 | 1994 |
Role of T cells in inflammation caused by adenovirus vectors in the brain. AP Byrnes, MJ Wood, HM Charlton Gene therapy 3 (7), 644-651, 1996 | 125 | 1996 |
Ex vivo adenovirus-mediated gene transfer and immunomodulatory protein production in human cornea HB Oral, DFP Larkin, Z Fehervari, AP Byrnes, AM Rankin, DO Haskard, ... Gene therapy 4 (7), 639-647, 1997 | 117 | 1997 |
Immune responses to adenoviral vectors during gene transfer in the brain K Kajiwara, AP Byrnes, HM Charlton, MJA Wood, KJ Wood Human gene therapy 8 (3), 253-265, 1997 | 110 | 1997 |
Adenovirus activates complement by distinctly different mechanisms in vitro and in vivo: indirect complement activation by virions in vivo J Tian, Z Xu, JS Smith, SE Hofherr, MA Barry, AP Byrnes Journal of virology 83 (11), 5648-5658, 2009 | 90 | 2009 |
Control of Sindbis virus infection by antibody in interferon-deficient mice AP Byrnes, JE Durbin, DE Griffin Journal of virology 74 (8), 3905-3908, 2000 | 78 | 2000 |
Interaction of systemically delivered adenovirus vectors with Kupffer cells in mouse liver JS Smith, Z Xu, J Tian, SC Stevenson, AP Byrnes Human gene therapy 19 (5), 547-554, 2008 | 68 | 2008 |
A γ34. 5 mutant of herpes simplex 1 causes severe inflammation in the brain MM McMenamin, AP Byrnes, HM Charlton, RS Coffin, DS Latchman, ... Neuroscience 83 (4), 1225-1237, 1998 | 67 | 1998 |
Circulating antibodies and macrophages as modulators of adenovirus pharmacology R Khare, ML Hillestad, Z Xu, AP Byrnes, MA Barry Journal of virology 87 (7), 3678-3686, 2013 | 61 | 2013 |
Local gene therapy with CTLA4‐immunoglobulin fusion protein in experimental allergic encephalomyelitis JL Croxford, JK O'Neill, RR Ali, K Browne, AP Byrnes, MJ Dallman, ... European journal of immunology 28 (12), 3904-3916, 1998 | 61 | 1998 |
Severe pulmonary pathology after intravenous administration of vectors in cirrhotic rats JS Smith, J Tian, JN Lozier, AP Byrnes Molecular Therapy 9 (6), 932-941, 2004 | 54 | 2004 |
Humoral immune responses to adenovirus vectors in the brain K Kajiwara, AP Byrnes, Y Ohmoto, HM Charlton, MJA Wood, KJ Wood Journal of Neuroimmunology 103 (1), 8-15, 2000 | 51 | 2000 |