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Allan R. Shepard
Allan R. Shepard
Senior Scientist, PCLS
Verified email at pcls.com
Title
Cited by
Cited by
Year
Non-secretion of mutant proteins of the glaucoma gene myocilin in cultured trabecular meshwork cells and in aqueous humor
N Jacobson, M Andrews, AR Shepard, D Nishimura, C Searby, JH Fingert, ...
Human molecular genetics 10 (2), 117-125, 2001
3472001
TGFβ2-induced changes in human trabecular meshwork: implications for intraocular pressure
DL Fleenor, AR Shepard, PE Hellberg, N Jacobson, IH Pang, AF Clark
Investigative ophthalmology & visual science 47 (1), 226-234, 2006
3432006
Adenoviral gene transfer of active human transforming growth factor-β2 elevates intraocular pressure and reduces outflow facility in rodent eyes
AR Shepard, JC Millar, IH Pang, N Jacobson, WH Wang, AF Clark
Investigative ophthalmology & visual science 51 (4), 2067-2076, 2010
2112010
Glucocorticoid induction of the glaucoma gene MYOC in human and monkey trabecular meshwork cells and tissues
AF Clark, HT Steely, JE Dickerson, S English-Wright, K Stropki, ...
Investigative ophthalmology & visual science 42 (8), 1769-1780, 2001
1942001
α1C (CaV1.2) L-type calcium channel mediates mechanosensitive calcium regulation
GL Lyford, PR Strege, A Shepard, Y Ou, L Ermilov, SM Miller, SJ Gibbons, ...
American Journal of Physiology-Cell Physiology 283 (3), C1001-C1008, 2002
1382002
Glaucoma-causing myocilin mutants require the Peroxisomal targeting signal-1 receptor (PTS1R) to elevate intraocular pressure
AR Shepard, N Jacobson, JC Millar, IH Pang, HT Steely, CC Searby, ...
Human molecular genetics 16 (6), 609-617, 2007
1252007
Evaluation of inducible nitric oxide synthase in glaucomatous optic neuropathy and pressure-induced optic nerve damage
IH Pang, EC Johnson, L Jia, WO Cepurna, AR Shepard, MR Hellberg, ...
Investigative ophthalmology & visual science 46 (4), 1313-1321, 2005
1242005
Exon-level expression profiling of ocular tissues
AH Wagner, VN Anand, WH Wang, JE Chatterton, D Sun, AR Shepard, ...
Experimental eye research 111, 105-111, 2013
1212013
Delayed secondary glucocorticoid responsiveness of MYOC in human trabecular meshwork cells
AR Shepard, N Jacobson, JH Fingert, EM Stone, VC Sheffield, AF Clark
Investigative ophthalmology & visual science 42 (13), 3173-3181, 2001
882001
Two CGTCA motifs and a GHF1/Pit1 binding site mediate cAMP-dependent protein kinase A regulation of human growth hormone gene expression in rat anterior pituitary GC cells.
AR Shepard, W Zhang, NL Eberhardt
Journal of Biological Chemistry 269 (3), 1804-1814, 1994
841994
Optimal procedure for extracting RNA from human ocular tissues and expression profiling of the congenital glaucoma gene FOXC1 using quantitative RT-PCR
WH Wang, LG McNatt, AR Shepard, N Jacobson, DY Nishimura, ...
Mol Vis 7, 89-94, 2001
672001
Magnetic bead capture of cDNAs from double-stranded plasmid cDNA libraries
AR Shepard, JL Rae
Nucleic acids research 25 (15), 3478-3480, 1997
611997
Thyroid hormone responsiveness in human growth hormone-related genes. Possible correlation with receptor-induced DNA conformational changes.
F Leidig, AR Shepard, WG Zhang, A Stelter, PA Cattini, JD Baxter, ...
Journal of Biological Chemistry 267 (2), 913-921, 1992
581992
RNAi inhibition of CTGF for treatment of ocular disorders
AR Shepard, IH Pang
US Patent 7,622,454, 2009
462009
TGF-β2–mediated ocular hypertension is attenuated in SPARC-null mice
SS Swaminathan, DJ Oh, MH Kang, AR Shepard, IH Pang, DJ Rhee
Investigative ophthalmology & visual science 55 (7), 4084-4097, 2014
452014
RNAi-mediated inhibition of ocular targets
AR Shepard, JE Chatterton, AF Clark, MB Wax
US Patent 7,592,324, 2009
452009
Kv3. 3 potassium channels in lens epithelium and corneal endothelium
JL RAE, AR SHEPARD
Experimental eye research 70 (3), 339-348, 2000
442000
An initiator element is required for maximal human chorionic somatomammotropin gene promoter and enhancer function
SW Jiang, AR Shepard, NL Eberhardt
Journal of Biological Chemistry 270 (8), 3683-3692, 1995
421995
Control of intraocular pressure using alk5 modulation agents
D Fleenor, IH Pang, A Shepard, M Hellberg, A Clark, P Klimko
US Patent App. 11/611,312, 2007
412007
RNAi-mediated inhibition of ocular hypertension targets
A Shepard, J Chatterton, A Clark
US Patent App. 11/344,702, 2006
382006
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