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Stephan Wullschleger
Stephan Wullschleger
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Cited by
Year
TOR signaling in growth and metabolism
S Wullschleger, R Loewith, MN Hall
Cell 124 (3), 471-484, 2006
69432006
Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control
R Loewith, E Jacinto, S Wullschleger, A Lorberg, JL Crespo, D Bonenfant, ...
Molecular cell 10 (3), 457-468, 2002
23292002
A colorectal cancer classification system that associates cellular phenotype and responses to therapy
A Sadanandam, CA Lyssiotis, K Homicsko, EA Collisson, WJ Gibb, ...
Nature medicine 19 (5), 619-625, 2013
10712013
Identification of Protor as a novel Rictor-binding component of mTOR complex-2
LR Pearce, X Huang, J Boudeau, R Pawłowski, S Wullschleger, M Deak, ...
Biochemical Journal 405 (3), 513-522, 2007
6242007
Important role of the LKB1–AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice
X Huang, S Wullschleger, N Shpiro, VA McGuire, K Sakamoto, YL Woods, ...
Biochemical Journal 412 (2), 211-221, 2008
4782008
Molecular organization of target of rapamycin complex 2
S Wullschleger, R Loewith, W Oppliger, MN Hall
Journal of Biological Chemistry 280 (35), 30697-30704, 2005
3202005
Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization
Y Kamada, Y Fujioka, NN Suzuki, F Inagaki, S Wullschleger, R Loewith, ...
Molecular and cellular biology 25 (16), 7239-7248, 2005
2712005
Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney
LR Pearce, EM Sommer, K Sakamoto, S Wullschleger, DR Alessi
Biochemical Journal 436 (1), 169-179, 2011
2292011
Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance
JR Bayascas, S Wullschleger, K Sakamoto, JM Garcia-Martinez, ...
Molecular and cellular biology 28 (10), 3258-3272, 2008
1622008
A cross-species analysis in pancreatic neuroendocrine tumors reveals molecular subtypes with distinctive clinical, metastatic, developmental, and metabolic characteristics
A Sadanandam, S Wullschleger, CA Lyssiotis, C Grötzinger, S Barbi, ...
Cancer discovery 5 (12), 1296-1313, 2015
1582015
Phenformin as prophylaxis and therapy in breast cancer xenografts
M Appleyard, KE Murray, PJ Coates, S Wullschleger, SE Bray, ...
British journal of cancer 106 (6), 1117-1122, 2012
1162012
PD-1-cis IL-2R agonism yields better effectors from stem-like CD8+ T cells
L Codarri Deak, V Nicolini, M Hashimoto, M Karagianni, PC Schwalie, ...
Nature 610 (7930), 161-172, 2022
942022
Regulation of the polarity kinases PAR-1/MARK by 14-3-3 interaction and phosphorylation
O Göransson, M Deak, S Wullschleger, NA Morrice, AR Prescott, ...
Journal of cell science 119 (19), 4059-4070, 2006
742006
Role of TAPP1 and TAPP2 adaptor binding to PtdIns(3,4)P2 in regulating insulin sensitivity defined by knock-in analysis
S Wullschleger, DH Wasserman, A Gray, K Sakamoto, DR Alessi
Biochemical Journal 434 (2), 265-274, 2011
642011
Secreted semaphorin 5A suppressed pancreatic tumour burden but increased metastasis and endothelial cell proliferation
A Sadanandam, SS Sidhu, S Wullschleger, S Singh, ML Varney, CS Yang, ...
British journal of cancer 107 (3), 501-507, 2012
562012
Effect of PI3K-and mTOR-specific inhibitors on spontaneous B-cell follicular lymphomas in PTEN/LKB1-deficient mice
JM Garcia-Martinez, S Wullschleger, G Preston, S Guichard, S Fleming, ...
British journal of cancer 104 (7), 1116-1125, 2011
552011
Formation of tissue factor-factor VIIa-factor Xa complex induces activation of the mTOR pathway which regulates migration of human breast cancer cells
X Jiang, S Zhu, TS Panetti, ME Bromberg
Thrombosis and haemostasis 100 (07), 127-133, 2008
522008
Interaction of TAPP adapter proteins with phosphatidylinositol (3, 4)‐bisphosphate regulates B‐cell activation and autoantibody production
I Landego, N Jayachandran, S Wullschleger, T Zhang, IW Gibson, A Miller, ...
European journal of immunology 42 (10), 2760-2770, 2012
432012
Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages
M Tichet, S Wullschleger, A Chryplewicz, N Fournier, R Marcone, ...
Immunity 56 (1), 162-179. e6, 2023
322023
Nanoparticle conjugation of human papillomavirus 16 E7-long peptides enhances therapeutic vaccine efficacy against solid tumors in mice.
WS Galliverti G, Tichet M, Domingos-Pereira S, Hauert S, Nardelli-Haefliger ...
Cancer Immunol Res., 2018
292018
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