Mutations in myosin light chain kinase cause familial aortic dissections L Wang, D Guo, J Cao, L Gong, KE Kamm, E Regalado, L Li, S Shete, ... The American Journal of Human Genetics 87 (5), 701-707, 2010 | 348 | 2010 |
IL-22 upregulates epithelial claudin-2 to drive diarrhea and enteric pathogen clearance PY Tsai, B Zhang, WQ He, JM Zha, MA Odenwald, G Singh, A Tamura, ... Cell host & microbe 21 (6), 671-681. e4, 2017 | 212 | 2017 |
Myosin light chain kinase is central to smooth muscle contraction and required for gastrointestinal motility in mice WQ He, YJ Peng, WC Zhang, N Lv, J Tang, C Chen, CH Zhang, S Gao, ... Gastroenterology 135 (2), 610-620. e2, 2008 | 194 | 2008 |
Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis WV Graham, W He, AM Marchiando, J Zha, G Singh, HS Li, A Biswas, ... Nature medicine 25 (4), 690-700, 2019 | 118 | 2019 |
Myosin phosphatase target subunit 1 (MYPT1) regulates the contraction and relaxation of vascular smooth muscle and maintains blood pressure YN Qiao, WQ He, CP Chen, CH Zhang, W Zhao, P Wang, L Zhang, YZ Wu, ... Journal of Biological Chemistry 289 (32), 22512-22523, 2014 | 117 | 2014 |
Contributions of myosin light chain kinase to regulation of epithelial paracellular permeability and mucosal homeostasis WQ He, J Wang, JY Sheng, JM Zha, WV Graham, JR Turner International journal of molecular sciences 21 (3), 993, 2020 | 93 | 2020 |
Interleukin 22 expands transit-amplifying cells while depleting Lgr5+ stem cells via inhibition of Wnt and notch signaling JM Zha, HS Li, Q Lin, WT Kuo, ZH Jiang, PY Tsai, N Ding, J Wu, SF Xu, ... Cellular and molecular gastroenterology and hepatology 7 (2), 255-274, 2019 | 90 | 2019 |
Myosin light chain kinase is necessary for tonic airway smooth muscle contraction WC Zhang, YJ Peng, GS Zhang, WQ He, YN Qiao, YY Dong, YQ Gao, ... Journal of Biological Chemistry 285 (8), 5522-5531, 2010 | 88 | 2010 |
Trio is a key guanine nucleotide exchange factor coordinating regulation of the migration and morphogenesis of granule cells in the developing cerebellum YJ Peng, WQ He, J Tang, T Tao, C Chen, YQ Gao, WC Zhang, XY He, ... Journal of biological chemistry 285 (32), 24834-24844, 2010 | 86 | 2010 |
Signaling through myosin light chain kinase in smooth muscles N Gao, J Huang, W He, M Zhu, KE Kamm, JT Stull Journal of Biological Chemistry 288 (11), 7596-7605, 2013 | 76 | 2013 |
Altered contractile phenotypes of intestinal smooth muscle in mice deficient in myosin phosphatase target subunit 1 WQ He, YN Qiao, YJ Peng, JM Zha, CH Zhang, C Chen, CP Chen, ... Gastroenterology 144 (7), 1456-1465. e5, 2013 | 75 | 2013 |
Myosin light chain kinase (MLCK) regulates cell migration in a myosin regulatory light chain phosphorylation-independent mechanism C Chen, T Tao, C Wen, WQ He, YN Qiao, YQ Gao, X Chen, P Wang, ... Journal of Biological Chemistry 289 (41), 28478-28488, 2014 | 74 | 2014 |
Role of myosin light chain kinase in regulation of basal blood pressure and maintenance of salt-induced hypertension WQ He, YN Qiao, CH Zhang, YJ Peng, C Chen, P Wang, YQ Gao, C Chen, ... American Journal of Physiology-Heart and Circulatory Physiology 301 (2 …, 2011 | 66 | 2011 |
In vivo roles for myosin phosphatase targeting subunit‐1 phosphorylation sites T694 and T852 in bladder smooth muscle contraction CP Chen, X Chen, YN Qiao, P Wang, WQ He, CH Zhang, W Zhao, ... The Journal of physiology 593 (3), 681-700, 2015 | 62 | 2015 |
In vitro and in vivo approaches to determine intestinal epithelial cell permeability BR Li, J Wu, HS Li, ZH Jiang, XM Zhou, CH Xu, N Ding, JM Zha, WQ He JoVE (Journal of Visualized Experiments), e57032, 2018 | 51 | 2018 |
The molecular basis of the genesis of basal tone in internal anal sphincter CH Zhang, P Wang, DH Liu, CP Chen, W Zhao, X Chen, C Chen, WQ He, ... Nature communications 7 (1), 11358, 2016 | 39 | 2016 |
Molecular mechanism of G1 arrest and cellular senescence induced by LEE011, a novel CDK4/CDK6 inhibitor, in leukemia cells YF Tao, NN Wang, LX Xu, ZH Li, XL Li, YY Xu, F Fang, M Li, GH Qian, ... Cancer cell international 17, 1-17, 2017 | 36 | 2017 |
Inhibiting PLK1 induces autophagy of acute myeloid leukemia cells via mammalian target of rapamycin pathway dephosphorylation YF Tao, ZH Li, WW Du, LX Xu, JL Ren, XL Li, F Fang, Y Xie, M Li, GH Qian, ... Oncology Reports 37 (3), 1419-1429, 2017 | 36 | 2017 |
Microfilament-binding properties of N-terminal extension of the isoform of smooth muscle long myosin light chain kinase CX Yang, HQ Chen, C Chen, WP Yu, WC Zhang, YJ Peng, WQ He, ... Cell research 16 (4), 367-376, 2006 | 31 | 2006 |
Constitutive phosphorylation of myosin phosphatase targeting subunit‐1 in smooth muscle MH Tsai, AN Chang, J Huang, W He, HL Sweeney, M Zhu, KE Kamm, ... The Journal of Physiology 592 (14), 3031-3051, 2014 | 28 | 2014 |