Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS ET Chouchani, VR Pell, E Gaude, D Aksentijević, SY Sundier, EL Robb, ... Nature 515 (7527), 431-435, 2014 | 2434 | 2014 |
Targeting an antioxidant to mitochondria decreases cardiac ischemia‐reperfusion injury VJ Adlam, JC Harrison, CM Porteous, AM James, RAJ Smith, MP Murphy, ... The FASEB Journal 19 (9), 1088-1095, 2005 | 710 | 2005 |
A unifying mechanism for mitochondrial superoxide production during ischemia-reperfusion injury ET Chouchani, VR Pell, AM James, LM Work, K Saeb-Parsy, C Frezza, ... Cell metabolism 23 (2), 254-263, 2016 | 671 | 2016 |
Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I ET Chouchani, C Methner, SM Nadtochiy, A Logan, VR Pell, S Ding, ... Nature medicine 19 (6), 753-759, 2013 | 643 | 2013 |
Lipophilic triphenylphosphonium cations as tools in mitochondrial bioenergetics and free radical biology MF Ross, GF Kelso, FH Blaikie, AM James, HM Cocheme, A Filipovska, ... Biochemistry (Moscow) 70, 222-230, 2005 | 548 | 2005 |
Interactions of Mitochondria-targeted and Untargeted Ubiquinones with the Mitochondrial Respiratory Chain and Reactive Oxygen Species: IMPLICATIONS FOR THE USE OF EXOGENOUS … AM James, HM Cochemé, RAJ Smith, MP Murphy Journal of Biological Chemistry 280 (22), 21295-21312, 2005 | 452 | 2005 |
Antioxidant and prooxidant properties of mitochondrial Coenzyme Q AM James, RAJ Smith, MP Murphy Archives of biochemistry and biophysics 423 (1), 47-56, 2004 | 371 | 2004 |
Complex I assembly into supercomplexes determines differential mitochondrial ROS production in neurons and astrocytes I Lopez-Fabuel, J Le Douce, A Logan, AM James, G Bonvento, ... Proceedings of the National Academy of Sciences 113 (46), 13063-13068, 2016 | 364 | 2016 |
Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix HM Cochemé, C Quin, SJ McQuaker, F Cabreiro, A Logan, TA Prime, ... Cell metabolism 13 (3), 340-350, 2011 | 319 | 2011 |
Mitochondrial redox signalling at a glance Y Collins, ET Chouchani, AM James, KE Menger, HM Cochemé, ... Journal of cell science 125 (4), 801-806, 2012 | 314 | 2012 |
Interaction of the mitochondria-targeted antioxidant MitoQ with phospholipid bilayers and ubiquinone oxidoreductases AM James, MS Sharpley, ARB Manas, FE Frerman, J Hirst, RAJ Smith, ... Journal of Biological Chemistry 282 (20), 14708-14718, 2007 | 267 | 2007 |
Fine-tuning the hydrophobicity of a mitochondria-targeted antioxidant J Asin-Cayuela, ARB Manas, AM James, RAJ Smith, MP Murphy FEBS letters 571 (1-3), 9-16, 2004 | 251 | 2004 |
Control of mitochondrial superoxide production by reverse electron transport at complex I EL Robb, AR Hall, TA Prime, S Eaton, M Szibor, C Viscomi, AM James, ... Journal of Biological Chemistry 293 (25), 9869-9879, 2018 | 250 | 2018 |
Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice S Rodriguez-Cuenca, HM Cochemé, A Logan, I Abakumova, TA Prime, ... Free Radical Biology and Medicine 48 (1), 161-172, 2010 | 239 | 2010 |
A mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury TA Prime, FH Blaikie, C Evans, SM Nadtochiy, AM James, CC Dahm, ... Proceedings of the National Academy of Sciences 106 (26), 10764-10769, 2009 | 238 | 2009 |
How mitochondrial damage affects cell function AM James, MP Murphy Journal of biomedical science 9, 475-487, 2002 | 231 | 2002 |
Rapid and extensive uptake and activation of hydrophobic triphenylphosphonium cations within cells MF Ross, TA Prime, I Abakumova, AM James, CM Porteous, RAJ Smith, ... Biochemical Journal 411 (3), 633-645, 2008 | 214 | 2008 |
Bioenergetic consequences of accumulating the common 4977‐bp mitochondrial DNA deletion WK Porteous, AM James, PW Sheard, CM Porteous, MA Packer, ... European Journal of Biochemistry 257 (1), 192-201, 1998 | 196 | 1998 |
Altered mitochondrial function in fibroblasts containing MELAS or MERRF mitochondrial DNA mutations AM JAMES, YH WEI, CY PANG, MP MURPHY Biochemical Journal 318 (2), 401-407, 1996 | 195 | 1996 |
Quantitation and origin of the mitochondrial membrane potential in human cells lacking mitochondrial DNA RD Appleby, WK Porteous, G Hughes, AM James, D Shannon, YH Wei, ... European journal of biochemistry 262 (1), 108-116, 1999 | 182 | 1999 |