| In vivo molecular evolution reveals biophysical origins of organismal fitness R Couñago, S Chen, Y Shamoo Molecular cell 22 (4), 441-449, 2006 | 108 | 2006 |
| Evolution of the B3 DNA binding superfamily: new insights into REM family gene diversification EAC Romanel, CG Schrago, RM Couñago, CAM Russo, M Alves-Ferreira PloS one 4 (6), e5791, 2009 | 104 | 2009 |
| Imperfect coordination chemistry facilitates metal ion release in the Psa permease RM Couñago, MP Ween, SL Begg, M Bajaj, J Zuegg, ML O'mara, ... Nature chemical biology 10 (1), 35-41, 2014 | 97 | 2014 |
| Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae SL Begg, BA Eijkelkamp, Z Luo, RM Couñago, JR Morey, MJ Maher, ... Nature communications 6 (1), 1-11, 2015 | 76 | 2015 |
| AdcA and AdcAII employ distinct zinc acquisition mechanisms and contribute additively to zinc homeostasis in Streptococcus pneumoniae CD Plumptre, BA Eijkelkamp, JR Morey, F Behr, RM Couñago, ... Molecular microbiology 91 (4), 834-851, 2014 | 70 | 2014 |
| Crystal Structure of Rice Importin-α and Structural Basis of Its Interaction with Plant-Specific Nuclear Localization Signals CW Chang, RLM Couñago, SJ Williams, M Bodén, B Kobe The Plant Cell 24 (12), 5074-5088, 2012 | 48 | 2012 |
| Distinctive conformation of minor site‐specific nuclear localization signals bound to Importin‐α CW Chang, RM Couñago, SJ Williams, M Bodén, B Kobe Traffic 14 (11), 1144-1154, 2013 | 44 | 2013 |
| An adaptive mutation in adenylate kinase that increases organismal fitness is linked to stability–activity trade-offs R Counago, CJ Wilson, MI Pena, P Wittung-Stafshede, Y Shamoo Protein Engineering, Design & Selection 21 (1), 19-27, 2008 | 40 | 2008 |
| Gene replacement of adenylate kinase in the gram-positive thermophile Geobacillus stearothermophilus disrupts adenine nucleotide homeostasis and reduces cell viability R Counago, Y Shamoo Extremophiles 9 (2), 135-144, 2005 | 33 | 2005 |
| Biochemical and structural characterization of alanine racemase from Bacillus anthracis (Ames) RM Couñago, M Davlieva, U Strych, RE Hill, KL Krause BMC structural biology 9 (1), 1-15, 2009 | 32 | 2009 |
| Prokaryotic substrate-binding proteins as targets for antimicrobial therapies. RL Couñago, CA McDevitt, MP Ween, B Kobe Current drug targets 13 (11), 1400-10., 2012 | 31 | 2012 |
| Novel bacterial MerR-like regulators: Their role in the response to carbonyl and nitrosative stress AG McEwan, KY Djoko, NH Chen, RLM Counago, SP Kidd, AJ Potter, ... Advances in microbial physiology 58, 1-22, 2011 | 27 | 2011 |
| Experimental evolution of adenylate kinase reveals contrasting strategies toward protein thermostability C Miller, M Davlieva, C Wilson, KI White, R Couñago, G Wu, JC Myers, ... Biophysical journal 99 (3), 887-896, 2010 | 23 | 2010 |
| A glutathione-dependent detoxification system is required for formaldehyde resistance and optimal survival of Neisseria meningitidis in biofilms NH Chen, RM Couñago, KY Djoko, MP Jennings, MA Apicella, B Kobe, ... Antioxidants & Redox Signaling 18 (7), 743-755, 2013 | 19 | 2013 |
| WNT activates the AAK1 kinase to promote clathrin-mediated endocytosis of LRP6 and establish a negative feedback loop MJ Agajanian, MP Walker, AD Axtman, RR Ruela-de-Sousa, DS Serafin, ... Cell reports 26 (1), 79-93. e8, 2019 | 18 | 2019 |
| Structures of Orf virus chemokine binding protein in complex with host chemokines reveal clues to broad binding specificity RM Couñago, KM Knapp, Y Nakatani, SB Fleming, M Corbett, LM Wise, ... Structure 23 (7), 1199-1213, 2015 | 17 | 2015 |
| The distribution of different classes of nuclear localization signals (NLSs) in diverse organisms and the utilization of the minor NLS-binding site in plantnuclear import … CW Chang, R Counago, S Williams, M Boden, B Kobe Plant Signaling & Behavior 8 (10), e25976, 2013 | 15 | 2013 |
| 1, 2, 6-thiadiazinones as novel narrow spectrum calcium/calmodulin-dependent protein kinase kinase 2 (CaMKK2) Inhibitors CRM Asquith, PH Godoi, RM Couñago, T Laitinen, JW Scott, ... Molecules 23 (5), 1221, 2018 | 12 | 2018 |
| In depth analysis of kinase cross screening data to identify chemical starting points for inhibition of the Nek family of kinases CI Wells, NR Kapadia, RM Couñago, DH Drewry MedChemComm 9 (1), 44-66, 2018 | 12 | 2018 |
| Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations RM Couñago, CK Allerston, P Savitsky, H Azevedo, PH Godoi, CI Wells, ... Scientific reports 7 (1), 1-12, 2017 | 9 | 2017 |
Bostjan KobeProfessor of Structural Biology, The University of QueenslandVerified email at uq.edu.au
