Bruno Mesmin
Bruno Mesmin
Institut de Pharmacologie MolÚculaire et Cellulaire, CNRS, UniversitÚ de Nice-Sophia Antipolis
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A four-step cycle driven by PI (4) P hydrolysis directs sterol/PI (4) P exchange by the ER-Golgi tether OSBP
B Mesmin, J Bigay, JM Von Filseck, S Lacas-Gervais, G Drin, B Antonny
Cell 155 (4), 830-843, 2013
ArfGAP1 responds to membrane curvature through the folding of a lipid packing sensor motif
J Bigay, JF Casella, G Drin, B Mesmin, B Antonny
The EMBO journal 24 (13), 2244-2253, 2005
Intracellular sterol dynamics
B Mesmin, FR Maxfield
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipidsá…, 2009
Sterols are mainly in the cytoplasmic leaflet of the plasma membrane and the endocytic recycling compartment in CHO cells
M Mondal, B Mesmin, S Mukherjee, FR Maxfield
Molecular biology of the cell 20 (2), 581-588, 2009
A phosphatidylinositol-4-phosphate powered exchange mechanism to create a lipid gradient between membranes
JM Von Filseck, S Vanni, B Mesmin, B Antonny, G Drin
Nature communications 6 (1), 1-12, 2015
Two lipid-packing sensor motifs contribute to the sensitivity of ArfGAP1 to membrane curvature
B Mesmin, G Drin, S Levi, M Rawet, D Cassel, J Bigay, B Antonny
Biochemistry 46 (7), 1779-1790, 2007
STARD4 abundance regulates sterol transport and sensing
B Mesmin, NH Pipalia, FW Lund, TF Ramlall, A Sokolov, D Eliezer, ...
Molecular biology of the cell 22 (21), 4004-4015, 2011
Sterol transfer, PI 4P consumption, and control of membrane lipid order by endogenous OSBP
B Mesmin, J Bigay, J Polidori, D Jamecna, S Lacas‐Gervais, B Antonny
The EMBO journal 36 (21), 3156-3174, 2017
Insights into the mechanisms of sterol transport between organelles
B Mesmin, B Antonny, G Drin
Cellular and molecular life sciences 70 (18), 3405-3421, 2013
The oxysterol-binding protein cycle: burning off PI (4) P to transport cholesterol
B Antonny, J Bigay, B Mesmin
Annual review of biochemistry 87, 809-837, 2018
Membrane curvature and the control of GTP hydrolysis in Arf1 during COPI vesicle formation
B Antonny, J Bigay, JF Casella, G Drin, B Mesmin, P Gounon
Biochemical Society Transactions 33 (4), 619-622, 2005
A phosphatidylserine-binding site in the cytosolic fragment of Clostridium sordellii lethal toxin facilitates glucosylation of membrane-bound Rac and is required for cytotoxicity
B Mesmin, K Robbe, B Geny, F Luton, G Brandolin, MR Popoff, B Antonny
Journal of Biological Chemistry 279 (48), 49876-49882, 2004
Discrete determinants in ArfGAP2/3 conferring Golgi localization and regulation by the COPI coat
L Kliouchnikov, J Bigay, B Mesmin, A Parnis, M Rawet, N Goldfeder, ...
Molecular biology of the cell 20 (3), 859-869, 2009
The counterflow transport of sterols and PI4P
B Mesmin, B Antonny
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipidsá…, 2016
Mitochondrial lipid transport and biosynthesis: a complex balance
B Mesmin
Journal of Cell Biology 214 (1), 9-11, 2016
Building lipid ‘PIPelines’ throughout the cell by ORP/Osh proteins
JM von Filseck, B Mesmin, J Bigay, B Antonny, G Drin
Biochemical Society Transactions 42 (5), 1465-1470, 2014
An intrinsically disordered region in OSBP acts as an entropic barrier to control protein dynamics and orientation at membrane contact sites
D Jamecna, J Polidori, B Mesmin, M Dezi, D Levy, J Bigay, B Antonny
Developmental cell 49 (2), 220-234. e8, 2019
Lipid exchange and signaling at ER–Golgi contact sites
B Mesmin, D Kovacs, G D’Angelo
Current opinion in cell biology 57, 8-15, 2019
Vitamin Currency in a Lipid Exchange Market
B Mesmin, B Antonny
Science 340 (6136), 1051-1052, 2013
Molecular and cellular dissection of the oxysterol-binding protein cycle through a fluorescent inhibitor
T PÚresse, D Kovacs, M Subra, J Bigay, MC Tsai, J Polidori, R Gautier, ...
Journal of Biological Chemistry 295 (13), 4277-4288, 2020
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