Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation M Fumagalli, F Rossiello, M Clerici, S Barozzi, D Cittaro, JM Kaplunov, ... Nature cell biology 14 (4), 355-365, 2012 | 890 | 2012 |
Telomere dysfunction in ageing and age-related diseases F Rossiello, D Jurk, JF Passos, F d’Adda di Fagagna Nature Cell Biology 24 (2), 135-147, 2022 | 273 | 2022 |
Stable cellular senescence is associated with persistent DDR activation M Fumagalli, F Rossiello, C Mondello, FA di Fagagna PloS one 9 (10), e110969, 2014 | 172 | 2014 |
Irreparable telomeric DNA damage and persistent DDR signalling as a shared causative mechanism of cellular senescence and ageing F Rossiello, U Herbig, MP Longhese, M Fumagalli, FA di Fagagna Current opinion in genetics & development 26, 89-95, 2014 | 149 | 2014 |
Inhibition of DNA damage response at telomeres improves the detrimental phenotypes of Hutchinson–Gilford Progeria Syndrome J Aguado, A Sola-Carvajal, V Cancila, G Revêchon, PF Ong, ... Nature communications 10 (1), 4990, 2019 | 104 | 2019 |
DNA damage response inhibition at dysfunctional telomeres by modulation of telomeric DNA damage response RNAs F Rossiello, J Aguado, S Sepe, F Iannelli, Q Nguyen, S Pitchiaya, ... Nature communications 8, 13980, 2017 | 102 | 2017 |
From “Cellular” RNA to “Smart” RNA: Multiple Roles of RNA in Genome Stability and Beyond F Michelini, AP Jalihal, S Francia, C Meers, ZT Neeb, F Rossiello, U Gioia, ... Chemical reviews 118 (8), 4365-4403, 2018 | 83 | 2018 |
Identification of fifteen novel germline variants in the BRCA1 3′ UTR reveals a variant in a breast cancer case that introduces a functional miR‐103 target site BL Brewster, F Rossiello, JD French, SL Edwards, M Wong, A Wronski, ... Human mutation 33 (12), 1665-1675, 2012 | 62 | 2012 |
Telomere damage promotes vascular smooth muscle cell senescence and immune cell recruitment after vessel injury AK Uryga, MOJ Grootaert, AM Garrido, S Oc, K Foote, J Chappell, ... Communications Biology 4 (1), 611, 2021 | 36 | 2021 |
DNA damage response at telomeres boosts the transcription of SARS‐CoV‐2 receptor ACE2 during aging S Sepe, F Rossiello, V Cancila, F Iannelli, V Matti, G Cicio, M Cabrini, ... EMBO reports 23 (2), e53658, 2022 | 31 | 2022 |
Target-enrichment sequencing for detailed characterization of small RNAs Q Nguyen, J Aguado, F Iannelli, AM Suzuki, F Rossiello, ... Nature protocols 13 (4), 768-786, 2018 | 9 | 2018 |
RNase A treatment and reconstitution with DNA damage response RNA in living cells as a tool to study the role of non-coding RNA in the formation of DNA damage response foci F Michelini, F Rossiello, F d’Adda di Fagagna, S Francia Nature Protocols 14 (5), 1489-1508, 2019 | 8 | 2019 |
ImmunoFISH for Adherent Cultured Mammalian Cells F Rossiello, M Fumagalli, FA di Fagagna Bio-protocol 3 (24), e999-e999, 2013 | 1 | 2013 |
Alternative lengthening of telomeres (ALT) cells viability is dependent on C-rich telomeric RNAs I Rosso, C Jones-Weinert, F Rossiello, M Cabrini, S Brambillasca, ... Nature Communications 14 (1), 7086, 2023 | | 2023 |
P1327: INHIBITING TELOMERIC DNA DAMAGE RESPONSE AS A NEW THERAPEUTIC STRATEGY TO REJUVENATE THE AGEING HEMATOPOIETIC SYSTEM A Oppezzo, S Sepe, F Rossiello, A Conti, E Marinelli, S Boggio, ADI Lillo, ... HemaSphere 7 (S3), e6000984, 2023 | | 2023 |
Therapeutic oligonucleotides FDA Di Fagagna, F Rossiello, J Aguado, C Jones-Weinert US Patent App. 17/065,409, 2021 | | 2021 |
RNA products and uses thereof FDA Di Fagagna, S Francia, F Michelini, F Rossiello US Patent 10,240,154, 2019 | | 2019 |
Therapeutic oligonucleotides FDA Di Fagagna, F Rossiello, J Aguado, C Jones-Weinert US Patent App. 15/748,133, 2018 | | 2018 |
STUDY ON THE GENETIC PREDISPOSITION TO BREAST CANCER AND THE DNA DAMAGE RESPONSE AT TELOMERES AND IN CELLULAR SENESCENCE F Rossiello Istituto Lombardo-Accademia di Scienze e Lettere-Rendiconti di Scienze, 2016 | | 2016 |
PERSISTENT DNA DAMAGE AT TELOMERES, CAUSED BY TRF2-MEDIATED DNA REPAIR INHIBITION, TRIGGERS CELLULAR SENESCENCE AND IS ASSOCIATED WITH PRIMATES AGEING F Rossiello Università degli Studi di Milano, 2014 | | 2014 |