Genome Engineering of Drosophila with the CRISPR RNA-Guided Cas9 Nuclease SJ Gratz, AM Cummings, JN Nguyen, DC Hamm, LK Donohue, ... Genetics 194 (4), 1029-1035, 2013 | 1322 | 2013 |
Zelda Binding in the Early Drosophila melanogaster Embryo Marks Regions Subsequently Activated at the Maternal-to-Zygotic Transition MM Harrison, XY Li, T Kaplan, MR Botchan, MB Eisen PLoS genetics 7 (10), e1002266, 2011 | 367 | 2011 |
Mechanisms regulating zygotic genome activation KN Schulz, MM Harrison Nature Reviews Genetics 20 (4), 221-234, 2019 | 356 | 2019 |
Safeguarding gene drive experiments in the laboratory OS Akbari, HJ Bellen, E Bier, SL Bullock, A Burt, GM Church, KR Cook, ... Science 349 (6251), 927-929, 2015 | 339 | 2015 |
A CRISPR view of development MM Harrison, BV Jenkins, KM O’Connor-Giles, J Wildonger Genes & development 28 (17), 1859-1872, 2014 | 300 | 2014 |
CRISPR‐Cas9 Genome Editing in Drosophila SJ Gratz, CD Rubinstein, MM Harrison, J Wildonger, KM O'Connor‐Giles Current protocols in molecular biology 111 (1), 31.2. 1-31.2. 20, 2015 | 236 | 2015 |
Establishment of regions of genomic activity during the Drosophila maternal to zygotic transition XY Li, MM Harrison, JE Villalta, T Kaplan, MB Eisen Elife 3, e03737, 2014 | 206 | 2014 |
Structural features of transcription factors associating with nucleosome binding MF Garcia, CD Moore, KN Schulz, O Alberto, G Donague, MM Harrison, ... Molecular cell 75 (5), 921-932. e6, 2019 | 180 | 2019 |
Some C. elegans class B synthetic multivulva proteins encode a conserved LIN-35 Rb-containing complex distinct from a NuRD-like complex MM Harrison, CJ Ceol, X Lu, HR Horvitz Proceedings of the National Academy of Sciences 103 (45), 16782-16787, 2006 | 177 | 2006 |
Zelda is differentially required for chromatin accessibility, transcription factor binding, and gene expression in the early Drosophila embryo KN Schulz, ER Bondra, A Moshe, JE Villalta, JD Lieb, T Kaplan, ... Genome research 25 (11), 1715-1726, 2015 | 172 | 2015 |
Advances in engineering the fly genome with the CRISPR-Cas system E Bier, MM Harrison, KM O’Connor-Giles, J Wildonger Genetics 208 (1), 1-18, 2018 | 162 | 2018 |
Dynamic multifactor hubs interact transiently with sites of active transcription in Drosophila embryos M Mir, MR Stadler, SA Ortiz, CE Hannon, MM Harrison, X Darzacq, ... Elife 7, e40497, 2018 | 161 | 2018 |
Temporal control of gene expression by the pioneer factor Zelda through transient interactions in hubs J Dufourt, A Trullo, J Hunter, C Fernandez, J Lazaro, M Dejean, L Morales, ... Nature Communications 9 (1), 5194, 2018 | 137 | 2018 |
CRISPR/Cas9-mediated genome engineering and the promise of designer flies on demand SJ Gratz, J Wildonger, MM Harrison, KM O'Connor-Giles Fly 7 (4), 249-255, 2013 | 135 | 2013 |
Continued activity of the pioneer factor Zelda is required to drive zygotic genome activation SL McDaniel, TJ Gibson, KN Schulz, MF Garcia, M Nevil, SU Jain, ... Molecular cell 74 (1), 185-195. e4, 2019 | 101 | 2019 |
H3 K27M and EZHIP impede H3K27-methylation spreading by inhibiting allosterically stimulated PRC2 SU Jain, AQ Rashoff, SD Krabbenhoft, D Hoelper, TJ Do, TJ Gibson, ... Molecular cell 80 (4), 726-735. e7, 2020 | 97 | 2020 |
Grainyhead and Zelda compete for binding to the promoters of the earliest-expressed Drosophila genes MM Harrison, MR Botchan, TW Cline Developmental biology 345 (2), 248-255, 2010 | 97 | 2010 |
Natalizumab plus interferon beta-1a reduces lesion formation in relapsing multiple sclerosis EW Radue, WH Stuart, PA Calabresi, C Confavreux, SL Galetta, ... Journal of the neurological sciences 292 (1-2), 28-35, 2010 | 84 | 2010 |
Regulatory principles governing the maternal-to-zygotic transition: insights from Drosophila melanogaster DC Hamm, MM Harrison Royal Society Open Biology 8 (12), 180183, 2018 | 77 | 2018 |
GAF is essential for zygotic genome activation and chromatin accessibility in the early Drosophila embryo MM Gaskill, TJ Gibson, ED Larson, MM Harrison Elife 10, e66668, 2021 | 73 | 2021 |