Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis GM DeNicola, FA Karreth, TJ Humpton, A Gopinathan, C Wei, K Frese, ... Nature 475 (7354), 106-109, 2011 | 1591 | 2011 |
Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs Y Tay, L Kats, L Salmena, D Weiss, SM Tan, U Ala, F Karreth, L Poliseno, ... Cell 147 (2), 344-357, 2011 | 903 | 2011 |
In vivo identification of tumor-suppressive PTEN ceRNAs in an oncogenic BRAF-induced mouse model of melanoma FA Karreth, Y Tay, D Perna, U Ala, SM Tan, AG Rust, G DeNicola, ... Cell 147 (2), 382-395, 2011 | 621 | 2011 |
ceRNA cross-talk in cancer: when ce-bling rivalries go awry FA Karreth, PP Pandolfi Cancer discovery 3 (10), 1113-1121, 2013 | 442* | 2013 |
Demonstration of a genetic therapeutic index for tumors expressing oncogenic BRAF by the kinase inhibitor SB-590885 AJ King, DR Patrick, RS Batorsky, ML Ho, HT Do, SY Zhang, R Kumar, ... Cancer research 66 (23), 11100-11105, 2006 | 270 | 2006 |
Integrated transcriptional and competitive endogenous RNA networks are cross-regulated in permissive molecular environments U Ala, FA Karreth, C Bosia, A Pagnani, R Taulli, V Léopold, Y Tay, ... Proceedings of the National Academy of Sciences 110 (18), 7154-7159, 2013 | 249 | 2013 |
The BRAF pseudogene functions as a competitive endogenous RNA and induces lymphoma in vivo FA Karreth, M Reschke, A Ruocco, C Ng, B Chapuy, V Léopold, ... Cell 161 (2), 319-332, 2015 | 237 | 2015 |
Platelet-released supernatants increase migration and proliferation, and decrease osteogenic differentiation of bone marrow-derived mesenchymal progenitor cells under in vitro … R Gruber, F Karreth, B Kandler, G Fuerst, A Rot, MB Fischer, G Watzek Platelets 15 (1), 29-35, 2004 | 218 | 2004 |
Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects L Kenner, A Hoebertz, FT Beil, N Keon, F Karreth, R Eferl, H Scheuch, ... The Journal of cell biology 164 (4), 613-623, 2004 | 210 | 2004 |
The Fos‐related antigen Fra‐1 is an activator of bone matrix formation R Eferl, A Hoebertz, AF Schilling, M Rath, F Karreth, L Kenner, M Amling, ... The EMBO journal 23 (14), 2789-2799, 2004 | 190 | 2004 |
Germline Brca2 heterozygosity promotes KrasG12D-driven carcinogenesis in a murine model of familial pancreatic cancer F Skoulidis, LD Cassidy, V Pisupati, JG Jonasson, H Bjarnason, ... Cancer cell 18 (5), 499-509, 2010 | 140 | 2010 |
Twist induces an epithelial-mesenchymal transition to facilitate tumor metastasis F Karreth, DA Tuveson Cancer biology & therapy 3 (11), 1058-1059, 2004 | 124 | 2004 |
BRAF inhibitor resistance mediated by the AKT pathway in an oncogenic BRAF mouse melanoma model D Perna, FA Karreth, AG Rust, PA Perez-Mancera, M Rashid, F Iorio, ... Proceedings of the National Academy of Sciences 112 (6), E536-E545, 2015 | 117 | 2015 |
C-Raf is required for the initiation of lung cancer by K-RasG12D FA Karreth, KK Frese, GM DeNicola, M Baccarini, DA Tuveson Cancer discovery 1 (2), 128-136, 2011 | 113 | 2011 |
Platelets are mitogenic for periosteum‐derived cells R Gruber, F Karreth, F Frommlet, MB Fischer, G Watzek Journal of Orthopaedic Research 21 (5), 941-948, 2003 | 103 | 2003 |
JunD regulates lymphocyte proliferation and T helper cell cytokine expression A Meixner, F Karreth, L Kenner, EF Wagner The EMBO journal 23 (6), 1325-1335, 2004 | 97 | 2004 |
The AP1 transcription factor Fra2 is required for efficient cartilage development F Karreth, A Hoebertz, H Scheuch, R Eferl, EF Wagner Development 131 (22), 5717-5725, 2004 | 86 | 2004 |
Platelet-released supernatants stimulate formation of osteoclast-like cells through a prostaglandin/RANKL-dependent mechanism R Gruber, F Karreth, MB Fischer, G Watzek Bone 30 (5), 726-732, 2002 | 77 | 2002 |
Modelling oncogenic Ras/Raf signalling in the mouse FA Karreth, DA Tuveson Current opinion in genetics & development 19 (1), 4-11, 2009 | 74 | 2009 |
C-Raf inhibits MAPK activation and transformation by B-RafV600E FA Karreth, GM DeNicola, SP Winter, DA Tuveson Molecular cell 36 (3), 477-486, 2009 | 70 | 2009 |