emma wincent
emma wincent
Senior research fellow at Karolinska Institutet, Institute of Environmental Medicine
Verified email at
Cited by
Cited by
Feedback control of AHR signalling regulates intestinal immunity
C Schiering, E Wincent, A Metidji, A Iseppon, Y Li, AJ Potocnik, ...
Nature 542 (7640), 242-245, 2017
The suggested physiologic aryl hydrocarbon receptor activator and cytochrome P4501 substrate 6-formylindolo [3, 2-b] carbazole is present in humans
E Wincent, N Amini, S Luecke, H Glatt, J Bergman, C Crescenzi, ...
Journal of biological chemistry 284 (5), 2690-2696, 2009
Inhibition of cytochrome P4501-dependent clearance of the endogenous agonist FICZ as a mechanism for activation of the aryl hydrocarbon receptor
E Wincent, J Bengtsson, AM Bardbori, T Alsberg, S Luecke, U Rannug, ...
Proceedings of the National Academy of Sciences 109 (12), 4479-4484, 2012
AHR in the intestinal microenvironment: safeguarding barrier function
B Stockinger, K Shah, E Wincent
Nature reviews Gastroenterology & hepatology 18 (8), 559-570, 2021
Quercetin, resveratrol, and curcumin are indirect activators of the aryl hydrocarbon receptor (AHR)
A Mohammadi-Bardbori, J Bengtsson, U Rannug, A Rannug, E Wincent
Chemical research in toxicology 25 (9), 1878-1884, 2012
Evidence for new light-independent pathways for generation of the endogenous aryl hydrocarbon receptor agonist FICZ
A Smirnova, E Wincent, L Vikström Bergander, T Alsberg, J Bergman, ...
Chemical research in toxicology 29 (1), 75-86, 2016
Metabolic fate of the Ah receptor ligand 6-formylindolo [3, 2-b] carbazole
L Bergander, E Wincent, A Rannug, M Foroozesh, W Alworth, U Rannug
Chemico-biological interactions 149 (2-3), 151-164, 2004
Aryl hydrocarbon receptor activation and developmental toxicity in zebrafish in response to soil extracts containing unsubstituted and oxygenated PAHs
E Wincent, ME Jonsson, M Bottai, S Lundstedt, K Dreij
Environmental science & technology 49 (6), 3869-3877, 2015
Toxicokinetics of Perfluorinated Alkyl Acids Influences Their Toxic Potency in the Zebrafish Embryo (Danio rerio)
C Vogs, G Johanson, M Näslund, S Wulff, M Sjödin, M Hellstrandh, ...
Environmental science & technology 53 (7), 3898-3907, 2019
Cellular accumulation and lipid binding of perfluorinated alkylated substances (PFASs)–A comparison with lysosomotropic drugs
DS Garcia, M Sjödin, M Hellstrandh, U Norinder, V Nikiforova, J Lindberg, ...
Chemico-biological interactions 281, 1-10, 2018
Biological effects of 6-formylindolo [3, 2-b] carbazole (FICZ) in vivo are enhanced by loss of CYP1A function in an Ahr2-dependent manner
E Wincent, A Kubota, A Timme-Laragy, ME Jönsson, ME Hahn, ...
Biochemical pharmacology 110, 117-129, 2016
Synthesis and biological evaluation of fused thio-and selenopyrans as new indolocarbazole analogues with aryl hydrocarbon receptor affinity
E Wincent, H Shirani, J Bergman, U Rannug, T Janosik
Bioorganic & medicinal chemistry 17 (4), 1648-1653, 2009
Induction and inhibition of human cytochrome P4501 by oxygenated polycyclic aromatic hydrocarbons
E Wincent, F Le Bihanic, K Dreij
Toxicology Research 5 (3), 788-799, 2016
Cytochrome P4501-inhibiting chemicals amplify aryl hydrocarbon receptor activation and IL-22 production in T helper 17 cells
C Schiering, A Vonk, S Das, B Stockinger, E Wincent
Biochemical pharmacology 151, 47-58, 2018
Cytochrome P450 1A1 gene regulation by UVB involves crosstalk between the aryl hydrocarbon receptor and nuclear factor κB
S Luecke, E Wincent, M Backlund, U Rannug, A Rannug
Chemico-biological interactions 184 (3), 466-473, 2010
Retene, pyrene and phenanthrene cause distinct molecular-level changes in the cardiac tissue of rainbow trout (Oncorhynchus mykiss) larvae, part 2–Proteomics and metabolomics
C Rigaud, A Eriksson, A Rokka, M Skaugen, J Lihavainen, M Keinänen, ...
Science of The Total Environment 746, 141161, 2020
Combination effects of AHR agonists and Wnt/β-catenin modulators in zebrafish embryos: implications for physiological and toxicological AHR functions
E Wincent, JJ Stegeman, ME Jönsson
Toxicology and applied pharmacology 284 (2), 163-179, 2015
Exposure to retene, fluoranthene, and their binary mixture causes distinct transcriptomic and apical outcomes in rainbow trout (Oncorhynchus mykiss) yolk sac alevins
ANM Eriksson, C Rigaud, A Krasnov, E Wincent, ER Vehniäinen
Aquatic Toxicology 244, 106083, 2022
Perfluorooctanesulfonic acid modulates barrier function and systemic T-cell homeostasis during intestinal inflammation
OE Diaz, C Sorini, RA Morales, X Luo, A Frede, AM Krais, MN Chávez, ...
Disease models & mechanisms 14 (12), dmm049104, 2021
Non-additive mixture effects of benzo [a] pyrene and pesticides in vitro and in vivo: Role of AhR signaling
BÜ Endirlik, E Wincent, K Dreij
Environmental Pollution 316, 120510, 2023
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