Periodic activation of Wnt/β-catenin signaling enhances somatic cell reprogramming mediated by cell fusion F Lluis, E Pedone, S Pepe, MP Cosma Cell stem cell 3 (5), 493-507, 2008 | 173 | 2008 |
The senotherapeutic drug ABT-737 disrupts aberrant p21 expression to restore liver regeneration in adult mice B Ritschka, T Knauer-Meyer, DS Gonçalves, A Mas, JL Plassat, M Durik, ... Genes & Development 34 (7-8), 489-494, 2020 | 71 | 2020 |
T-cell factor 3 (Tcf3) deletion increases somatic cell reprogramming by inducing epigenome modifications F Lluis, L Ombrato, E Pedone, S Pepe, BJ Merrill, MP Cosma Proceedings of the National Academy of Sciences 108 (29), 11912-11917, 2011 | 55 | 2011 |
Regulation of gene expression and signaling pathway activity in mammalian cells by automated microfluidics feedback control L Postiglione, S Napolitano, E Pedone, DL Rocca, F Aulicino, M Santorelli, ... ACS synthetic biology 7 (11), 2558-2565, 2018 | 51 | 2018 |
β-catenin fluctuates in mouse ESCs and is essential for Nanog-mediated reprogramming of somatic cells to pluripotency L Marucci, E Pedone, U Di Vicino, B Sanuy-Escribano, M Isalan, ... Cell reports 8 (6), 1686-1696, 2014 | 49 | 2014 |
A tunable dual-input system for on-demand dynamic gene expression regulation E Pedone, L Postiglione, F Aulicino, DL Rocca, S Montes-Olivas, ... Nature communications 10 (1), 4481, 2019 | 41 | 2019 |
Role of β-catenin activation levels and fluctuations in controlling cell fate E Pedone, L Marucci Genes 10 (2), 176, 2019 | 34 | 2019 |
A new cryptic host defense peptide identified in human 11-hydroxysteroid dehydrogenase-1 β-like: from in silico identification to experimental evidence A Bosso, L Pirone, R Gaglione, K Pane, A Del Gatto, L Zaccaro, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (9), 2342-2353, 2017 | 32 | 2017 |
Canonical Wnt pathway controls mESC self-renewal through inhibition of spontaneous differentiation via β-Catenin/TCF/LEF functions F Aulicino, E Pedone, F Sottile, F Lluis, L Marucci, MP Cosma Stem Cell Reports 15 (3), 646-661, 2020 | 31 | 2020 |
Cheetah: a computational toolkit for cybergenetic control E Pedone, I De Cesare, CG Zamora-Chimal, D Haener, L Postiglione, ... ACS Synthetic Biology 10 (5), 979-989, 2021 | 26 | 2021 |
Modeling dynamics and function of bone marrow cells in mouse liver regeneration E Pedone, VA Olteanu, L Marucci, MI Munoz-Martin, SA Youssef, ... Cell reports 18 (1), 107-121, 2017 | 26 | 2017 |
The Wnt/β-catenin signaling pathway tips the balance between apoptosis and reprograming of cell fusion hybrids F Lluis, E Pedone, S Pepe, MP Cosma Stem Cells 28 (11), 1940-1949, 2010 | 25 | 2010 |
An extended model for culture-dependent heterogenous gene expression and proliferation dynamics in mouse embryonic stem cells S Godwin, D Ward, E Pedone, M Homer, AG Fletcher, L Marucci NPJ systems biology and applications 3 (1), 19, 2017 | 24 | 2017 |
ChipSeg: An automatic tool to segment bacterial and mammalian cells cultured in microfluidic devices I De Cesare, CG Zamora-Chimal, L Postiglione, M Khazim, E Pedone, ... ACS omega 6 (4), 2473-2476, 2021 | 13 | 2021 |
A flow‐through microfluidic chip for continuous dielectrophoretic separation of viable and non‐viable human T‐cells A Mustafa, E Pedone, L Marucci, D Moschou, MD Lorenzo Electrophoresis 43 (3), 501-508, 2022 | 10 | 2022 |
Towards automated control of embryonic stem cell pluripotency M Khazim, L Postiglione, E Pedone, DL Rocca, C Zahra, L Marucci IFAC-PapersOnLine 52 (26), 82-87, 2019 | 10 | 2019 |
A dual druggable genome-wide siRNA and compound library screening approach identifies modulators of parkin recruitment to mitochondria HL Scott, N Buckner, F Fernandez-Albert, E Pedone, L Postiglione, G Shi, ... Journal of Biological Chemistry 295 (10), 3285-3300, 2020 | 9 | 2020 |
A microfluidic/microscopy-based platform for on-chip controlled gene expression in mammalian cells M Khazim, E Pedone, L Postiglione, D di Bernardo, L Marucci Synthetic Gene Circuits: Methods and Protocols, 205-219, 2021 | 7 | 2021 |
Culturing pluripotent stem cells: State of the art, challenges and future opportunities A La Regina, E Pedone, L Marucci Current Opinion in Systems Biology 28, 100364, 2021 | 2 | 2021 |
Development of a single layer microfluidic device for dynamic stimulation, culture and imaging of mammalian cells A Mustafa, E Pedone, A La Regina, A Erten, L Marucci bioRxiv, 2022.03. 14.484262, 2022 | 1 | 2022 |