Synthesis, characterization, inhibition effects, and molecular docking studies as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors of novel … N Lolak, S Akocak, C Türkeş, P Taslimi, M Işık, Ş Beydemir, İ Gülçin, ... Bioorganic chemistry 100, 103897, 2020 | 150 | 2020 |
An approach to clarify the effect mechanism of glyphosate on body malformations during embryonic development of zebrafish (Daino rerio) E Sulukan, M Köktürk, H Ceylan, Ş Beydemir, M Işik, M Atamanalp, ... Chemosphere 180, 77-85, 2017 | 117 | 2017 |
Synthesis, characterisation, biological evaluation and in silico studies of sulphonamide Schiff bases M Durgun, C Türkeş, M Işık, Y Demir, A Saklı, A Kuru, A Güzel, ... Journal of enzyme inhibition and medicinal chemistry 35 (1), 950-962, 2020 | 98 | 2020 |
Oxidative stress and mRNA expression of acetylcholinesterase in the leukocytes of ischemic patients M Işık, Ş Beydemir, A Yılmaz, ME Naldan, HE Aslan, İ Gülçin Biomedicine & pharmacotherapy 87, 561-567, 2017 | 98 | 2017 |
Benzenesulfonamide derivatives as potent acetylcholinesterase, α-glycosidase, and glutathione S-transferase inhibitors: biological evaluation and molecular docking studies P Taslimi, M Işık, F Türkan, M Durgun, C Türkeş, İ Gülçin, Ş Beydemir Journal of Biomolecular Structure and Dynamics 39 (15), 5449-5460, 2021 | 93 | 2021 |
Changes in the anti-oxidant system in adult epilepsy patients receiving anti-epileptic drugs M Işık, Y Demir, M Kırıcı, R Demir, F Şimşek, Ş Beydemir Archives of physiology and biochemistry 121 (3), 97-102, 2015 | 90 | 2015 |
Phenolic compounds inhibit the aldose reductase enzyme from the sheep kidney Y Demir, M Işık, İ Gülçin, Ş Beydemir Journal of biochemical and molecular toxicology 31 (9), e21936, 2017 | 89 | 2017 |
Synthesis, characterization, and inhibition study of novel substituted phenylureido sulfaguanidine derivatives as α‐glycosidase and cholinesterase inhibitors S Akocak, P Taslimi, N Lolak, M Işık, M Durgun, Y Budak, C Türkeş, ... Chemistry & biodiversity 18 (4), e2000958, 2021 | 75 | 2021 |
Synthesis, characterization, biological evaluation, and in silico studies of novel 1, 3‐diaryltriazene‐substituted sulfathiazole derivatives M Işık, S Akocak, N Lolak, P Taslimi, C Türkeş, İ Gülçin, M Durgun, ... Archiv Der Pharmazie 353 (9), 2000102, 2020 | 74 | 2020 |
Novel inhibitors with sulfamethazine backbone: synthesis and biological study of multi-target cholinesterases and α-glucosidase inhibitors C Türkeş, S Akocak, M Işık, N Lolak, P Taslimi, M Durgun, İ Gülçin, ... Journal of Biomolecular Structure and Dynamics 40 (19), 8752-8764, 2022 | 72 | 2022 |
Molecular docking and investigation of 4-(benzylideneamino)-and 4-(benzylamino)-benzenesulfonamide derivatives as potent AChE inhibitors M Işık, Y Demir, M Durgun, C Türkeş, A Necip, Ş Beydemir Chemical Papers 74 (5), 1395-1405, 2020 | 71 | 2020 |
Benzenesulfonamide derivatives containing imine and amine groups: Inhibition on human paraoxonase and molecular docking studies M Işık, Ş Beydemir, Y Demir, M Durgun, C Türkeş, A Nasır, A Necip, ... International journal of biological macromolecules 146, 1111-1123, 2020 | 69 | 2020 |
Biological effects of bis-hydrazone compounds bearing isovanillin moiety on the aldose reductase G Yapar, HE Duran, N Lolak, S Akocak, C Türkeş, M Durgun, M Işık, ... Bioorganic chemistry 117, 105473, 2021 | 58 | 2021 |
Mannich reaction derived novel boron complexes with amine-bis (phenolate) ligands: Synthesis, spectroscopy and in vitro/in silico biological studies A Kilic, L Beyazsakal, M Işık, C Türkeş, A Necip, K Takım, Ş Beydemir Journal of Organometallic Chemistry 927, 121542, 2020 | 51 | 2020 |
Determination of antioxidant properties of Gypsophila bitlisensis bark H Tohma, M Isik, M Korkmaz, E Bursal, I Gulcin, E Koksal Int J Pharmacol 11 (4), 366-71, 2015 | 50 | 2015 |
Novel bis-ureido-substituted sulfaguanidines and sulfisoxazoles as carbonic anhydrase and acetylcholinesterase inhibitors N Lolak, S Akocak, M Durgun, HE Duran, A Necip, C Türkeş, M Işık, ... Molecular Diversity 27 (4), 1735-1749, 2023 | 45 | 2023 |
The binding mechanisms and inhibitory effect of intravenous anesthetics on AChE in vitro and in vivo: kinetic analysis and molecular docking M Işık Neurochemical research 44 (9), 2147-2155, 2019 | 37 | 2019 |
High stability of immobilized acetylcholinesterase on chitosan beads M Işık ChemistrySelect 5 (15), 4623-4627, 2020 | 31 | 2020 |
Phytochemical analysis of Paliurus spina-christi fruit and its effects on oxidative stress and antioxidant enzymes in streptozotocin-induced diabetic rats K Takım, M Işık Applied biochemistry and biotechnology 191 (4), 1353-1368, 2020 | 30 | 2020 |
The impact of some phenolic compounds on serum acetylcholinesterase: Kinetic analysis of an enzyme/inhibitor interaction and molecular docking study M Işık, Ş Beydemir Journal of Biomolecular Structure and Dynamics 39 (17), 6515-6523, 2021 | 29 | 2021 |