Mehmet Kesimer
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A periciliary brush promotes the lung health by separating the mucus layer from airway epithelia
B Button, LH Cai, C Ehre, M Kesimer, DB Hill, JK Sheehan, RC Boucher, ...
Science 337 (6097), 937-941, 2012
Clinical significance of symptoms in smokers with preserved pulmonary function
PG Woodruff, RG Barr, E Bleecker, SA Christenson, D Couper, JL Curtis, ...
New England Journal of Medicine 374 (19), 1811-1821, 2016
Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense
M Kesimer, M Scull, B Brighton, G DeMaria, K Burns, W O'Neal, ...
The FASEB Journal 23 (6), 1858, 2009
Design of the subpopulations and intermediate outcomes in COPD study (SPIROMICS)
D Couper, LM LaVange, ML Han, RG Barr, E Bleecker, EA Hoffman, ...
Thorax 69 (5), 492-495, 2014
E-cigarette use causes a unique innate immune response in the lung, involving increased neutrophilic activation and altered mucin secretion
B Reidel, G Radicioni, PW Clapp, AA Ford, S Abdelwahab, ME Rebuli, ...
American journal of respiratory and critical care medicine 197 (4), 492-501, 2018
Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure
AG Henderson, C Ehre, B Button, LH Abdullah, LH Cai, MW Leigh, ...
The Journal of clinical investigation 124 (7), 3047-3060, 2014
Airway mucin concentration as a marker of chronic bronchitis
M Kesimer, AA Ford, A Ceppe, G Radicioni, R Cao, CW Davis, ...
New England Journal of Medicine 377 (10), 911-922, 2017
Nanoparticle analysis of circulating cell-derived vesicles in ovarian cancer patients
C Gercel-Taylor, S Atay, RH Tullis, M Kesimer, DD Taylor
Analytical biochemistry 428 (1), 44-53, 2012
Localization of secretory mucins MUC5AC and MUC5B in normal/healthy human airways
K Okuda, G Chen, DB Subramani, M Wolf, RC Gilmore, T Kato, ...
American journal of respiratory and critical care medicine 199 (6), 715-727, 2019
At the root: defining and halting progression of early chronic obstructive pulmonary disease
FJ Martinez, MLK Han, JP Allinson, RG Barr, RC Boucher, PMA Calverley, ...
American journal of respiratory and critical care medicine 197 (12), 1540-1551, 2018
Molecular organization of the mucins and glycocalyx underlying mucus transport over mucosal surfaces of the airways
M Kesimer, C Ehre, KA Burns, CW Davis, JK Sheehan, RJ Pickles
Mucosal immunology 6 (2), 379-392, 2013
Tracheobronchial air-liquid interface cell culture: a model for innate mucosal defense of the upper airways?
M Kesimer, S Kirkham, RJ Pickles, AG Henderson, NE Alexis, G DeMaria, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 296 (1 …, 2009
Reduced three-dimensional motility in dehydrated airway mucus prevents neutrophil capture and killing bacteria on airway epithelial surfaces
H Matsui, MW Verghese, M Kesimer, UE Schwab, SH Randell, ...
The journal of immunology 175 (2), 1090-1099, 2005
Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis
CR Esther Jr, MS Muhlebach, C Ehre, DB Hill, MC Wolfgang, M Kesimer, ...
Science translational medicine 11 (486), eaav3488, 2019
Chronic exposure to beta-blockers attenuates inflammation and mucin content in a murine asthma model
LP Nguyen, O Omoluabi, S Parra, JM Frieske, C Clement, ...
American journal of respiratory cell and molecular biology 38 (3), 256-262, 2008
Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells
S Atay, C Gercel-Taylor, M Kesimer, DD Taylor
Experimental cell research 317 (8), 1192-1202, 2011
The relationship of mucus concentration (hydration) to mucus osmotic pressure and transport in chronic bronchitis
WH Anderson, RD Coakley, B Button, AG Henderson, KL Zeman, ...
American journal of respiratory and critical care medicine 192 (2), 182-190, 2015
Unpacking a gel-forming mucin: a view of MUC5B organization after granular release
M Kesimer, AM Makhov, JD Griffith, P Verdugo, JK Sheehan
American Journal of Physiology-Lung Cellular and Molecular Physiology 298 (1 …, 2010
Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort
G Radicioni, A Ceppe, AA Ford, NE Alexis, RG Barr, ER Bleecker, ...
The Lancet Respiratory Medicine 9 (11), 1241-1254, 2021
Physical characterization and profiling of airway epithelial derived exosomes using light scattering
M Kesimer, R Gupta
Methods 87, 59-63, 2015
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