| Autocrine TGF-β and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts Y Kojima, A Acar, EN Eaton, KT Mellody, C Scheel, I Ben-Porath, ... Proceedings of the National Academy of Sciences 107 (46), 20009-20014, 2010 | 927 | 2010 |
| Anti-estrogen resistance in human breast tumors is driven by JAG1-NOTCH4-dependent cancer stem cell activity BM Simoes, CS O’Brien, R Eyre, A Silva, L Yu, A Sarmiento-Castro, ... Cell reports 12 (12), 1968-1977, 2015 | 198 | 2015 |
| TGF-beta receptor type-2 expression in cancer-associated fibroblasts regulates breast cancer cell growth and survival and is a prognostic marker in pre-menopausal breast cancer S Busch, A Acar, Y Magnusson, P Gregersson, L Rydén, G Landberg Oncogene 34 (1), 27-38, 2013 | 120 | 2013 |
| Exploiting evolutionary steering to induce collateral drug sensitivity in cancer A Acar, D Nichol, J Fernandez-Mateos, GD Cresswell, I Barozzi, SP Hong, ... Nature communications 11 (1), 1923, 2020 | 111 | 2020 |
| Subclonal reconstruction of tumors by using machine learning and population genetics G Caravagna, T Heide, MJ Williams, L Zapata, D Nichol, K Chkhaidze, ... Nature genetics 52 (9), 898-907, 2020 | 110 | 2020 |
| Dishevelled limits Notch signalling through inhibition of CSL GM Collu, A Hidalgo-Sastre, A Acar, L Bayston, C Gildea, MK Leverentz, ... Development 139 (23), 4405-4415, 2012 | 88 | 2012 |
| A role for notch signalling in breast cancer and endocrine resistance A Acar, BM Simões, RB Clarke, K Brennan Stem cells international 2016 (1), 2498764, 2016 | 82 | 2016 |
| Evolutionary dynamics of residual disease in human glioblastoma I Spiteri, G Caravagna, GD Cresswell, A Vatsiou, D Nichol, A Acar, ... Annals of Oncology 30 (3), 456-463, 2019 | 72 | 2019 |
| The spatiotemporal evolution of lymph node spread in early breast cancer P Barry, A Vatsiou, I Spiteri, D Nichol, GD Cresswell, A Acar, N Trahearn, ... Clinical Cancer Research 24 (19), 4763-4770, 2018 | 39 | 2018 |
| Inhibition of Wnt signalling by Notch via two distinct mechanisms A Acar, A Hidalgo-Sastrem, MK Leverentz, CG Mills, W Simon, B Martin, ... Scientific Reports, 9096, 2021 | 38 | 2021 |
| Immune selection determines tumor antigenicity and influences response to checkpoint inhibitors L Zapata, G Caravagna, MJ Williams, E Lakatos, K AbdulJabbar, ... Nature Genetics 55 (3), 451-460, 2023 | 34 | 2023 |
| Experimental generation of carcinoma-associated fibroblasts (CAFs) from human mammary fibroblasts UM Polanska, A Acar, A Orimo JoVE (Journal of Visualized Experiments), e3201, 2011 | 32 | 2011 |
| Systems biology and experimental model systems of cancer GD Yalcin, N Danisik, RC Baygin, A Acar Journal of Personalized Medicine 10 (4), 180, 2020 | 22 | 2020 |
| Increased TRIM31 gene expression is positively correlated with SARS-CoV-2 associated genes TMPRSS2 and TMPRSS4 in gastrointestinal cancers MA Temena, A Acar Scientific Reports 12 (1), 11763, 2022 | 12 | 2022 |
| Current Technologies and Future Perspectives in Immunotherapy towards a Clinical Oncology Approach S Adhikary, S Pathak, V Palani, A Acar, A Banerjee, NI Al-Dewik, ... Biomedicines 12 (1), 217, 2024 | 6 | 2024 |
| Identification of collateral sensitivity and evolutionary landscape of chemotherapy-induced drug resistance using cellular barcoding technology N Danisik, KC Yilmaz, A Acar Frontiers in Pharmacology 14, 1178489, 2023 | 5 | 2023 |
| Pan-Cancer Analysis of the COVID-19 Causal Gene SLC6A20 A Acar ACS omega 8 (14), 13153-13161, 2023 | 4 | 2023 |
| Investigation of evolutionary dynamics for drug resistance in 3D spheroid model system using cellular barcoding technology GD Yalcin, KC Yilmaz, T Dilber, A Acar Plos one 18 (9), e0291942, 2023 | 3 | 2023 |
| Optimizing cancer therapy: a review of the multifaceted effects of metronomic chemotherapy OY Basar, S Mohammed, MW Qoronfleh, A Acar Frontiers in Cell and Developmental Biology 12, 1369597, 2024 | 2 | 2024 |
| Characterization of dabrafenib-induced drug insensitivity via cellular barcoding and collateral sensitivity to second-line therapeutics RC Baygin, KC Yilmaz, A Acar Scientific Reports 14 (1), 286, 2024 | 2 | 2024 |
