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Christopher J. Halbrook
Christopher J. Halbrook
Verified email at uci.edu - Homepage
Title
Cited by
Cited by
Year
Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion
CM Sousa, DE Biancur, X Wang, CJ Halbrook, MH Sherman, LI Zhang, ...
Nature 536 (7617), 479-483, 2016
9752016
EGF receptor is required for KRAS-induced pancreatic tumorigenesis
CM Ardito, BM Grüner, KK Takeuchi, C Lubeseder-Martellato, ...
Cancer cell 22 (3), 304-317, 2012
5352012
Employing metabolism to improve the diagnosis and treatment of pancreatic cancer
CJ Halbrook, CA Lyssiotis
Cancer cell 31 (1), 5-19, 2017
3532017
Macrophage-released pyrimidines inhibit gemcitabine therapy in pancreatic cancer
CJ Halbrook, C Pontious, I Kovalenko, L Lapienyte, S Dreyer, HJ Lee, ...
Cell metabolism 29 (6), 1390-1399. e6, 2019
3282019
Regulatory T-cell depletion alters the tumor microenvironment and accelerates pancreatic carcinogenesis
Y Zhang, J Lazarus, NG Steele, W Yan, HJ Lee, ZC Nwosu, CJ Halbrook, ...
Cancer discovery 10 (3), 422-439, 2020
2682020
Pancreatic cancer: Advances and challenges
CJ Halbrook, CA Lyssiotis, MP di Magliano, A Maitra
Cell 186 (8), 1729-1754, 2023
1842023
Inhibition of hedgehog signaling alters fibroblast composition in pancreatic cancer
NG Steele, G Biffi, SB Kemp, Y Zhang, D Drouillard, LJ Syu, Y Hao, ...
Clinical Cancer Research 27 (7), 2023-2037, 2021
1772021
Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth
AS Krall, PJ Mullen, F Surjono, M Momcilovic, EW Schmid, CJ Halbrook, ...
Cell metabolism 33 (5), 1013-1026. e6, 2021
1452021
GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis
DM Kremer, BS Nelson, L Lin, EL Yarosz, CJ Halbrook, SA Kerk, ...
Nature communications 12 (1), 4860, 2021
1422021
Purine metabolism regulates DNA repair and therapy resistance in glioblastoma
W Zhou, Y Yao, AJ Scott, K Wilder-Romans, JJ Dresser, CK Werner, ...
Nature communications 11 (1), 3811, 2020
1272020
PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice
CYC Wu, ES Carpenter, KK Takeuchi, CJ Halbrook, LV Peverley, H Bien, ...
Gastroenterology 147 (6), 1405-1416. e7, 2014
1222014
Identification and manipulation of biliary metaplasia in pancreatic tumors
KE DelGiorno, JC Hall, KK Takeuchi, FC Pan, CJ Halbrook, ...
Gastroenterology 146 (1), 233-244. e5, 2014
1212014
Endoplasmic reticulum–associated degradation regulates mitochondrial dynamics in brown adipocytes
Z Zhou, M Torres, H Sha, CJ Halbrook, F Van den Bergh, RB Reinert, ...
Science 368 (6486), 54-60, 2020
1132020
PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance
N Roy, KK Takeuchi, JM Ruggeri, P Bailey, D Chang, J Li, L Leonhardt, ...
Genes & development 30 (24), 2669-2683, 2016
962016
Interleukin 22 signaling regulates acinar cell plasticity to promote pancreatic tumor development in mice
MP Lanfranca, Y Zhang, A Girgis, S Kasselman, J Lazarus, I Kryczek, ...
Gastroenterology 158 (5), 1417-1432. e11, 2020
612020
Hyaluronic acid fuels pancreatic cancer cell growth
PK Kim, CJ Halbrook, SA Kerk, M Radyk, S Wisner, DM Kremer, ...
Elife 10, e62645, 2021
602021
Mitogen-activated protein kinase kinase activity maintains acinar-to-ductal metaplasia and is required for organ regeneration in pancreatitis
CJ Halbrook, HJ Wen, JM Ruggeri, KK Takeuchi, Y Zhang, ...
Cellular and molecular gastroenterology and hepatology 3 (1), 99-118, 2017
582017
Metabolism and epigenetics of pancreatic cancer stem cells
MP Lanfranca, JK Thompson, F Bednar, C Halbrook, C Lyssiotis, B Levi, ...
Seminars in cancer biology 57, 19-26, 2019
502019
Menin regulates the serine biosynthetic pathway in Ewing sarcoma
LK Svoboda, SSK Teh, S Sud, S Kerk, A Zebolsky, S Treichel, D Thomas, ...
The Journal of pathology 245 (3), 324-336, 2018
442018
Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context
SA Kerk, L Lin, AL Myers, DJ Sutton, A Andren, P Sajjakulnukit, L Zhang, ...
Elife 11, e73245, 2022
372022
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