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EGF receptor is required for KRAS-induced pancreatic tumorigenesis CM Ardito, BM Grüner, KK Takeuchi, C Lubeseder-Martellato, ... Cancer cell 22 (3), 304-317, 2012 | 536 | 2012 |
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Macrophage-released pyrimidines inhibit gemcitabine therapy in pancreatic cancer CJ Halbrook, C Pontious, I Kovalenko, L Lapienyte, S Dreyer, HJ Lee, ... Cell metabolism 29 (6), 1390-1399. e6, 2019 | 330 | 2019 |
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Inhibition of hedgehog signaling alters fibroblast composition in pancreatic cancer NG Steele, G Biffi, SB Kemp, Y Zhang, D Drouillard, LJ Syu, Y Hao, ... Clinical Cancer Research 27 (7), 2023-2037, 2021 | 178 | 2021 |
Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth AS Krall, PJ Mullen, F Surjono, M Momcilovic, EW Schmid, CJ Halbrook, ... Cell metabolism 33 (5), 1013-1026. e6, 2021 | 148 | 2021 |
GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis DM Kremer, BS Nelson, L Lin, EL Yarosz, CJ Halbrook, SA Kerk, ... Nature communications 12 (1), 4860, 2021 | 141 | 2021 |
Purine metabolism regulates DNA repair and therapy resistance in glioblastoma W Zhou, Y Yao, AJ Scott, K Wilder-Romans, JJ Dresser, CK Werner, ... Nature communications 11 (1), 3811, 2020 | 128 | 2020 |
PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice CYC Wu, ES Carpenter, KK Takeuchi, CJ Halbrook, LV Peverley, H Bien, ... Gastroenterology 147 (6), 1405-1416. e7, 2014 | 122 | 2014 |
Identification and manipulation of biliary metaplasia in pancreatic tumors KE DelGiorno, JC Hall, KK Takeuchi, FC Pan, CJ Halbrook, ... Gastroenterology 146 (1), 233-244. e5, 2014 | 121 | 2014 |
Endoplasmic reticulum–associated degradation regulates mitochondrial dynamics in brown adipocytes Z Zhou, M Torres, H Sha, CJ Halbrook, F Van den Bergh, RB Reinert, ... Science 368 (6486), 54-60, 2020 | 116 | 2020 |
PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance N Roy, KK Takeuchi, JM Ruggeri, P Bailey, D Chang, J Li, L Leonhardt, ... Genes & development 30 (24), 2669-2683, 2016 | 97 | 2016 |
Hyaluronic acid fuels pancreatic cancer cell growth PK Kim, CJ Halbrook, SA Kerk, M Radyk, S Wisner, DM Kremer, ... Elife 10, e62645, 2021 | 63 | 2021 |
Interleukin 22 signaling regulates acinar cell plasticity to promote pancreatic tumor development in mice MP Lanfranca, Y Zhang, A Girgis, S Kasselman, J Lazarus, I Kryczek, ... Gastroenterology 158 (5), 1417-1432. e11, 2020 | 63 | 2020 |
Mitogen-activated protein kinase kinase activity maintains acinar-to-ductal metaplasia and is required for organ regeneration in pancreatitis CJ Halbrook, HJ Wen, JM Ruggeri, KK Takeuchi, Y Zhang, ... Cellular and molecular gastroenterology and hepatology 3 (1), 99-118, 2017 | 58 | 2017 |
Metabolism and epigenetics of pancreatic cancer stem cells MP Lanfranca, JK Thompson, F Bednar, C Halbrook, C Lyssiotis, B Levi, ... Seminars in cancer biology 57, 19-26, 2019 | 51 | 2019 |
Menin regulates the serine biosynthetic pathway in Ewing sarcoma LK Svoboda, SSK Teh, S Sud, S Kerk, A Zebolsky, S Treichel, D Thomas, ... The Journal of pathology 245 (3), 324-336, 2018 | 44 | 2018 |
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