|Inhibitory effects of isatin Mannich bases on carbonic anhydrases, acetylcholinesterase, and butyrylcholinesterase|
DO Ozgun, C Yamali, HI Gul, P Taslimi, I Gulcin, T Yanik, CT Supuran
Journal of enzyme inhibition and medicinal chemistry 31 (6), 1498-1501, 2016
|Synthesis, molecular modeling, and biological evaluation of 4‐[5‐aryl‐3‐(thiophen‐2‐yl)‐4,5‐dihydro‐1H‐pyrazol‐1‐yl] benzenesulfonamides toward …|
C Yamali, HI Gul, A Ece, P Taslimi, I Gulcin
Chemical biology & drug design 91 (4), 854-866, 2018
|Synthesis of 4-(2-substituted hydrazinyl) benzenesulfonamides and their carbonic anhydrase inhibitory effects|
HI Gul, K Kucukoglu, C Yamali, S Bilginer, H Yuca, I Ozturk, P Taslimi, ...
Journal of enzyme inhibition and medicinal chemistry 31 (4), 568-573, 2016
|Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity|
DO Ozgun, HI Gul, C Yamali, H Sakagami, I Gulcin, M Sukuroglu, ...
Bioorganic chemistry 84, 511-517, 2019
|New anticancer drug candidates sulfonamides as selective hCA IX or hCA XII inhibitors|
HI Gul, C Yamali, H Sakagami, A Angeli, J Leitans, A Kazaks, K Tars, ...
Bioorganic chemistry 77, 411-419, 2018
|Synthesis, cytotoxicity and carbonic anhydrase inhibitory activities of new pyrazolines|
K Kucukoglu, F Oral, T Aydin, C Yamali, O Algul, H Sakagami, I Gulcin, ...
Journal of enzyme inhibition and medicinal chemistry 31 (sup4), 20-24, 2016
|Synthesis and bioactivities of halogen bearing phenolic chalcones and their corresponding bis Mannich bases|
C Yamali, HI Gul, H Sakagami, CT Supuran
Journal of enzyme inhibition and medicinal chemistry 31 (sup4), 125-131, 2016
|The inhibitory effects of phenolic Mannich bases on carbonic anhydrase I and II isoenzymes|
C Yamali, M Tugrak, HI Gul, M Tanc, CT Supuran
Journal of enzyme inhibition and medicinal chemistry 31 (6), 1678-1681, 2016
|Designing, synthesis and bioactivities of 4-[3-(4-hydroxyphenyl)-5-aryl-4, 5-dihydro-pyrazol-1-yl] benzenesulfonamides|
HI Gul, E Mete, SE Eren, H Sakagami, C Yamali, CT Supuran
Journal of enzyme inhibition and medicinal chemistry 32 (1), 169-175, 2017
|Synthesis of mono Mannich bases of 2-(4-hydroxybenzylidene)-2, 3-dihydroinden-1-one and evaluation of their cytotoxicities|
M Tugrak, C Yamali, H Sakagami, HI Gul
Journal of enzyme inhibition and medicinal chemistry 31 (5), 818-823, 2016
|Microwave-assisted synthesis and bioevaluation of new sulfonamides|
HI Gul, C Yamali, F Yesilyurt, H Sakagami, K Kucukoglu, I Gulcin, M Gul, ...
Journal of enzyme inhibition and medicinal chemistry 32 (1), 369-374, 2017
|Carbonic anhydrase inhibition and cytotoxicity studies of Mannich base derivatives of thymol|
H Inci Gul, C Yamali, A Tugce Yasa, E Unluer, H Sakagami, M Tanc, ...
Journal of enzyme inhibition and medicinal chemistry 31 (6), 1375-1380, 2016
|Anticancer effects of new dibenzenesulfonamides by inducing apoptosis and autophagy pathways and their carbonic anhydrase inhibitory effects on hCA I, hCA II, hCA IX, hCA XII …|
HI Gul, C Yamali, M Bulbuller, PB Kirmizibayrak, M Gul, A Angeli, S Bua, ...
Bioorganic chemistry 78, 290-297, 2018
|Synthesis, structure elucidation, and in vitro pharmacological evaluation of novel polyfluoro substituted pyrazoline type sulfonamides as multi-target agents for inhibition of …|
C Yamali, HI Gul, C Kazaz, S Levent, I Gulcin
Bioorganic chemistry 96, 103627, 2020
|Synthesis and structure elucidation of 1-(2, 5/3, 5-difluorophenyl)-3-(2, 3/2, 4/2, 5/3, 4-dimethoxyphenyl)-2-propen-1-ones as anticancer agents|
C Yamali, DO Ozgun, HI Gul, H Sakagami, C Kazaz, N Okudaira
Medicinal Chemistry Research 26 (9), 2015-2023, 2017
|Synthesis and cytotoxic activities of difluoro-dimethoxy chalcones|
C Yamali, H Inci Gul, D Ozmen Ozgun, H Sakagam, N Umemura, C Kazaz, ...
Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2017
|Curcumin analogue 1, 5-bis (4-hydroxy-3-((4-methylpiperazin-1-yl) methyl) phenyl) penta-1, 4-dien-3-one mediates growth arrest and apoptosis by targeting the PI3K/AKT/mTOR and …|
G Badr, HI Gul, C Yamali, AAM Mohamed, BM Badr, M Gul, AA Markeb, ...
Bioorganic chemistry 78, 46-57, 2018
|Synthesis of some 3 (2 H)-pyridazinone and 1 (2 H)-phthalazinone derivatives incorporating aminothiazole moiety and investigation of their antioxidant, acetylcholinesterase …|
C Yamalı, HO Gülcan, B Kahya, S Çobanoğlu, MK Şüküroğlu, DS Doğruer
Medicinal Chemistry Research 24 (3), 1210-1217, 2015
|Synthesis, biological evaluation and in silico modelling studies of 1, 3, 5-trisubstituted pyrazoles carrying benzenesulfonamide as potential anticancer agents and selective …|
C Yamali, HI Gul, A Ece, S Bua, A Angeli, H Sakagami, E Sahin, ...
Bioorganic chemistry 92, 103222, 2019
|Cytotoxicity, apoptosis, and QSAR studies of phenothiazine derived methoxylated chalcones as anticancer drug candidates|
HI Gul, C Yamali, G Gunesacar, H Sakagami, N Okudaira, Y Uesawa, ...
Medicinal Chemistry Research 27 (10), 2366-2378, 2018