The diverse chemistry of oxazol-5-(4 H)-ones JS Fisk, RA Mosey, JJ Tepe Chemical Society Reviews 36 (9), 1432-1440, 2007 | 291 | 2007 |
Stereoselective syntheses of quaternary substituted α-amino acids using oxazol-5-(4H)-ones RA Mosey, JS Fisk, JJ Tepe Tetrahedron: Asymmetry 19 (24), 2755-2762, 2008 | 155 | 2008 |
Mechanistic insights into the multistage gas-phase fragmentation behavior of phosphoserine-and phosphothreonine-containing peptides AM Palumbo, JJ Tepe, GE Reid Journal of Proteome Research 7 (2), 771-779, 2008 | 128 | 2008 |
Stereoselective Synthesis of Highly Substituted Δ-Pyrrolines: exo-Selective 1,3-Dipolar Cycloaddition Reactions with Azlactones S Peddibhotla, JJ Tepe Journal of the American Chemical Society 126 (40), 12776-12777, 2004 | 112 | 2004 |
Inhibition of cytokine production by hymenialdisine derivatives V Sharma, TA Lansdell, G Jin, JJ Tepe Journal of medicinal chemistry 47 (14), 3700-3703, 2004 | 112 | 2004 |
Proteasome activation as a new therapeutic approach to target proteotoxic disorders E Njomen, JJ Tepe Journal of medicinal chemistry 62 (14), 6469-6481, 2019 | 90 | 2019 |
Potent inhibition of checkpoint kinase activity by a hymenialdisine-derived indoloazepine V Sharma, JJ Tepe Bioorganic & medicinal chemistry letters 14 (16), 4319-4321, 2004 | 86 | 2004 |
Small molecule enhancement of 20S proteasome activity targets intrinsically disordered proteins CL Jones, E Njomen, B Sjögren, TS Dexheimer, JJ Tepe ACS chemical biology 12 (9), 2240-2247, 2017 | 84 | 2017 |
One-Pot Friedel− Crafts/Robinson− Gabriel Synthesis of Oxazoles Using Oxazolone Templates M Keni, JJ Tepe The Journal of Organic Chemistry 70 (10), 4211-4213, 2005 | 84 | 2005 |
Highly diastereoselective multicomponent synthesis of unsymmetrical imidazolines S Peddibhotla, S Jayakumar, JJ Tepe Organic Letters 4 (20), 3533-3535, 2002 | 71 | 2002 |
Reactivity of oxazol-5-(4H)-ones and their application toward natural product synthesis NM Hewlett, CD Hupp, JJ Tepe Synthesis, 2825-2839, 2009 | 69 | 2009 |
Increased extracellular pressure stimulates tumor proliferation by a mechanosensitive calcium channel and PKC-β MD Basson, B Zeng, C Downey, MP Sirivelu, JJ Tepe Molecular oncology 9 (2), 513-526, 2015 | 67 | 2015 |
Total synthesis of the natural product (±)-dibromophakellin and analogues NM Hewlett, JJ Tepe Organic letters 13 (17), 4550-4553, 2011 | 66 | 2011 |
Perspectives on SARS-CoV-2 main protease inhibitors K Gao, R Wang, J Chen, JJ Tepe, F Huang, GW Wei Journal of medicinal chemistry 64 (23), 16922-16955, 2021 | 65 | 2021 |
FR900482 class of anti-tumor drugs cross-links oncoprotein HMG I/Y to DNA in vivo L Beckerbauer, JJ Tepe, J Cullison, R Reeves, RM Williams Chemistry & Biology 7 (10), 805-812, 2000 | 64 | 2000 |
DNA cross-linking by a phototriggered dehydromonocrotaline progenitor JJ Tepe, RM Williams Journal of the American Chemical Society 121 (13), 2951-2955, 1999 | 62 | 1999 |
Small molecule modulation of proteasome assembly E Njomen, PA Osmulski, CL Jones, M Gaczynska, JJ Tepe Biochemistry 57 (28), 4214-4224, 2018 | 61 | 2018 |
Diastereochemical diversity of imidazoline scaffolds via substrate controlled TMSCl mediated cycloaddition of azlactones V Sharma, JJ Tepe Organic letters 7 (22), 5091-5094, 2005 | 61 | 2005 |
Palau’amine and related oroidin alkaloids dibromophakellin and dibromophakellstatin inhibit the human 20S proteasome TA Lansdell, NM Hewlett, AP Skoumbourdis, MD Fodor, IB Seiple, S Su, ... Journal of Natural Products 75 (5), 980-985, 2012 | 58 | 2012 |
Sensitization of tumor cells toward chemotherapy: enhancing the efficacy of camptothecin with imidazolines V Sharma, TA Lansdell, S Peddibhotla, JJ Tepe Chemistry & biology 11 (12), 1689-1699, 2004 | 58 | 2004 |