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Peter Lachmann
Peter Lachmann
Emeritus Professor of Immunology, Cambridge University
Verified email at cam.ac.uk
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CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells.
A Davies, DL Simmons, G Hale, RA Harrison, H Tighe, PJ Lachmann, ...
The Journal of experimental medicine 170 (3), 637-654, 1989
7311989
Human protectin (CD59), an 18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers.
S Meri, BP Morgan, A Davies, RH Daniels, MG Olavesen, H Waldmann, ...
immunology 71 (1), 1, 1990
6911990
Systemic lupus erythematosus, complement deficiency, and apoptosis
MC Pickering, M Botto, PR Taylor, PJ Lachmann, MJ Walport
Advances in immunology 76, 227-324, 2001
6142001
Membrane complement receptor type three (CR3) has lectin-like properties analogous to bovine conglutinin as functions as a receptor for zymosan and rabbit erythrocytes as well …
GD Ross, JA Cain, PJ Lachmann
Journal of immunology (Baltimore, Md.: 1950) 134 (5), 3307-3315, 1985
5601985
Complement technology
PJ Lachmann, MJ Hobart, WP Aston
Handbook of experimental immunology 1, 5A, 1978
4521978
AIDS—an immunologic reevaluation
M Seligmann, L Chess, JL Fahey, AS Fauci, PJ Lachmann, J L'Age-Stehr, ...
New England Journal of Medicine 311 (20), 1286-1292, 1984
3831984
The immunosuppressive drug thalidomide induces T helper cell type 2 (Th2) and concomitantly inhibits Th1 cytokine production in mitogen‐and antigen‐stimulated human peripheral …
SM McHugh, IR Rifkin, J Deighton, AB Wilson, PJ Lachmann, ...
Clinical & Experimental Immunology 99 (2), 160-167, 1995
3601995
Mechanism of first-dose cytokine-release syndrome by CAMPATH 1-H: involvement of CD16 (FcgammaRIII) and CD11a/CD18 (LFA-1) on NK cells.
MG Wing, T Moreau, J Greenwood, RM Smith, G Hale, J Isaacs, ...
The Journal of clinical investigation 98 (12), 2819-2826, 1996
3581996
The localization of in vivo bound complement in tissue sections
PJ Lachmann, HJ Muller-Eberhard, HG Kunkel, F Paronetto
The Journal of Experimental Medicine 115 (1), 63-82, 1962
3421962
Disease-associated loss of erythrocyte complement receptors (CR1, C3b receptors) in patients with systemic lupus erythematosus and other diseases involving autoantibodies and …
GD Ross, WJ Yount, MJ Walport, JB Winfield, CJ Parker, CR Fuller, ...
Journal of immunology (Baltimore, Md.: 1950) 135 (3), 2005-2014, 1985
3391985
Reactive lysis: The complement-mediated lysis of unsensitized cells: II. The characterization of activated reactor as C56 and the participation of C8 and C9
PJ Lachmann, RA Thompson
The Journal of experimental medicine 131 (4), 643-657, 1970
3251970
Clinical aspects of immunology
RRA Coombs, PGH Gell, PJ Lachmann
Blackwell Scientific Publications, 1975
3191975
Type C retrovirus inactivation by human complement is determined by both the viral genome and the producer cell
Y Takeuchi, FL Cosset, PJ Lachmann, H Okada, RA Weiss, MK Collins
Journal of virology 68 (12), 8001-8007, 1994
3081994
Specificity of membrane complement receptor type three (CR3) for ß-glucans
GD Ross, JA Cain, BL Myones, SL Newman, PJ Lachmann
Complement 4 (2), 61-74, 1987
3081987
The demonstration in human serum of “conglutinogen-activating factor” and its effect on the third component of complement
PJ Lachmann, HJ Müller-Eberhard
The Journal of Immunology 100 (4), 691-698, 1968
2711968
The amplification loop of the complement pathways
PJ Lachmann
Advances in immunology 104, 115-149, 2009
2702009
The physiological breakdown of the third component of human complement
RA Harrison, PJ Lachmann
Molecular immunology 17 (1), 9-20, 1980
2561980
Reactive lysis: the complement-mediated lysis of unsensitized cells: I. The characterization of the indicator factor and its identification as C7
RA Thompson, PJ Lachmann
The Journal of Experimental Medicine 131 (4), 629-641, 1970
2531970
Bee venom immunotherapy induces a shift in cytokine responses from a TH‐2 to a TH‐1 dominant pattern: comparison of rush and conventional immunotherapy
SM McHugh, J Deighton, AG Stewart, PJ Lachmann, PW Ewan
Clinical & Experimental Allergy 25 (9), 828-838, 1995
2511995
Breakdown of C3 after complement activation. Identification of a new fragment C3g, using monoclonal antibodies.
PJ Lachmann, MK Pangburn, RG Oldroyd
The Journal of experimental medicine 156 (1), 205-216, 1982
2511982
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