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| A causative link between the structure of aberrant protein oligomers and their toxicity S Campioni, B Mannini, M Zampagni, A Pensalfini, C Parrini, ... Nature chemical biology 6 (2), 140-147, 2010 | 624 | 2010 |
| Atomic view of a toxic amyloid small oligomer A Laganowsky, C Liu, MR Sawaya, JP Whitelegge, J Park, M Zhao, ... Science 335 (6073), 1228-1231, 2012 | 607 | 2012 |
| Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction JL Tomic, A Pensalfini, E Head, CG Glabe Neurobiology of disease 35 (3), 352-358, 2009 | 416 | 2009 |
| Annular protofibrils are a structurally and functionally distinct type of amyloid oligomer R Kayed, A Pensalfini, L Margol, Y Sokolov, F Sarsoza, E Head, J Hall, ... Journal of Biological Chemistry 284 (7), 4230-4237, 2009 | 406 | 2009 |
| Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques JH Lee, DS Yang, CN Goulbourne, E Im, P Stavrides, A Pensalfini, ... Nature neuroscience 25 (6), 688-701, 2022 | 289 | 2022 |
| Protein misfolding, congophilia, oligomerization, and defective amyloid processing in preeclampsia IA Buhimschi, UA Nayeri, G Zhao, LL Shook, A Pensalfini, EF Funai, ... Science translational medicine 6 (245), 245ra92-245ra92, 2014 | 236 | 2014 |
| Out-of-register β-sheets suggest a pathway to toxic amyloid aggregates C Liu, M Zhao, L Jiang, PN Cheng, J Park, MR Sawaya, A Pensalfini, ... Proceedings of the National Academy of Sciences 109 (51), 20913-20918, 2012 | 208 | 2012 |
| Evidence that the rab5 effector APPL1 mediates APP-βCTF-induced dysfunction of endosomes in Down syndrome and Alzheimer’s disease S Kim, Y Sato, PS Mohan, C Peterhoff, A Pensalfini, A Rigoglioso, Y Jiang, ... Molecular psychiatry 21 (5), 707-716, 2016 | 204 | 2016 |
| Conformation dependent monoclonal antibodies distinguish different replicating strains or conformers of prefibrillar Aβ oligomers R Kayed, I Canto, L Breydo, S Rasool, T Lukacsovich, J Wu, R Albay, ... Molecular neurodegeneration 5, 1-10, 2010 | 180 | 2010 |
| Dysfunction of autophagy and endosomal-lysosomal pathways: Roles in pathogenesis of Down syndrome and Alzheimer's Disease DJ Colacurcio, A Pensalfini, Y Jiang, RA Nixon Free Radical Biology and Medicine 114, 40-51, 2018 | 161 | 2018 |
| Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaques A Pensalfini, R Albay III, S Rasool, JW Wu, A Hatami, H Arai, L Margol, ... Neurobiology of disease 71, 53-61, 2014 | 116 | 2014 |
| Curcumin protects cardiac cells against ischemia-reperfusion injury: effects on oxidative stress, NF-κB, and JNK pathways C Fiorillo, M Becatti, A Pensalfini, C Cecchi, L Lanzilao, G Donzelli, ... Free Radical Biology and Medicine 45 (6), 839-846, 2008 | 108 | 2008 |
| Insights into the molecular basis of the differing susceptibility of varying cell types to the toxicity of amyloid aggregates C Cecchi, S Baglioni, C Fiorillo, A Pensalfini, G Liguri, D Nosi, S Rigacci, ... Journal of cell science 118 (15), 3459-3470, 2005 | 108 | 2005 |
| New therapeutic targets in Alzheimer's disease: brain deregulation of calcium and zinc C Corona, A Pensalfini, V Frazzini, SL Sensi Cell death & disease 2 (6), e176-e176, 2011 | 98 | 2011 |
| Seladin‐1/DHCR24 protects neuroblastoma cells against Aβ toxicity by increasing membrane cholesterol content C Cecchi, F Rosati, A Pensalfini, L Formigli, D Nosi, G Liguri, F Dichiara, ... Journal of cellular and molecular medicine 12 (5b), 1990-2002, 2008 | 97 | 2008 |
| A protective role for lipid raft cholesterol against amyloid-induced membrane damage in human neuroblastoma cells C Cecchi, D Nichino, M Zampagni, C Bernacchioni, E Evangelisti, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1788 (10), 2204-2216, 2009 | 84 | 2009 |
| Endosomal dysfunction induced by directly overactivating Rab5 recapitulates prodromal and neurodegenerative features of Alzheimer’s disease A Pensalfini, S Kim, S Subbanna, C Bleiwas, CN Goulbourne, ... Cell reports 33 (8), 2020 | 71 | 2020 |
| Increased susceptibility to amyloid toxicity in familial Alzheimer's fibroblasts C Cecchi, C Fiorillo, S Baglioni, A Pensalfini, S Bagnoli, B Nacmias, ... Neurobiology of aging 28 (6), 863-876, 2007 | 71 | 2007 |
| Membrane cholesterol enrichment prevents Aβ-induced oxidative stress in Alzheimer's fibroblasts A Pensalfini, M Zampagni, G Liguri, M Becatti, E Evangelisti, C Fiorillo, ... Neurobiology of Aging 32 (2), 210-222, 2011 | 55 | 2011 |
