AMP‐activated protein kinase couples 3‐bromopyruvate‐induced energy depletion to apoptosis via activation of FoxO3a and upregulation of proapoptotic Bcl‐2 proteins C Bodur, B Karakas, AC Timucin, T Tezil, H Basaga Molecular Carcinogenesis 55 (11), 1584-1597, 2016 | 24 | 2016 |
Biphasic ROS production, p53 and BIK dictate the mode of cell death in response to DNA damage in colon cancer cells O Kutuk, N Aytan, B Karakas, AG Kurt, U Acikbas, SG Temel, H Basaga PloS one 12 (8), e0182809, 2017 | 21 | 2017 |
Cytotoxic and apoptotic effects of novel pyrrolo [2, 3-d] pyrimidine derivatives containing urea moieties on cancer cell lines Z Kilic-Kurt, F Bakar-Ates, B Karakas, Ö Kütük Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2018 | 15 | 2018 |
Distinct apoptotic blocks mediate resistance to panHER inhibitors in HER2+ breast cancer cells B Karakas, Y Ozmay, H Basaga, O Gul, O Kutuk Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1865 (8), 1073-1087, 2018 | 13 | 2018 |
RAB25 confers resistance to chemotherapy by altering mitochondrial apoptosis signaling in ovarian cancer cells SG Temel, A Giray, B Karakas, O Gul, I Kozanoglu, H Celik, H Basaga, ... Apoptosis 25 (11), 799-816, 2020 | 12 | 2020 |
Mitochondrial estrogen receptors alter mitochondrial priming and response to endocrine therapy in breast cancer cells B Karakas, Y Aka, A Giray, SG Temel, U Acikbas, H Basaga, O Gul, ... Cell death discovery 7 (1), 1-14, 2021 | 9 | 2021 |
Kinome-wide RNAi screening for mediators of ABT-199 resistance in breast cancer cells identifies Wee1 as a novel therapeutic target Y Aka, B Karakas, U Acikbas, H Basaga, O Gul, O Kutuk The International Journal of Biochemistry & Cell Biology 137, 106028, 2021 | 4 | 2021 |
Impact of a maternal high-fat diet on mouse placental epigenetic programming B Karakas SLU, Dept. of Animal Breeding and Genetics, 2015 | 2 | 2015 |
Mitochondrial estrogen receptors alter mitochondrial priming and response to endocrine therapy in breast cancer cells. O Kutuk, B Karakas, Y Aka, A Giray, H Basaga, U Acikbas, O Gul, ... | | 2021 |
Identifying Bcl-2 family protein dependencies in tumors using dimerization specific antibody biomarkers as a method for predicting response to apoptosis inducing therapies B Karakas, SR Jean, M Narovlyansky, S Kumar, S Gillies, S Krajewski, ... Cancer Research 79 (13 Supplement), 3164-3164, 2019 | | 2019 |
Identifying Mcl-1 protein dependencies using dimerization-specific antibody biomarker for predicting response to targeted apoptosis inducing therapies. MH Cardone, SR Jean, B Karakas, S Kumar, M Narovlyansky, B Lim Journal of Clinical Oncology 37 (15_suppl), 7038-7038, 2019 | | 2019 |
A novel homozygous nonsense mutation in the calpastatin (CAST) gene associated with peeling skin phenotype in a child H Saricaoglu, S Temel, O Zorlu, B Turkgenc, O Kutuk, B Karakas, U Kiran, ... | | 2018 |
Delineating the mechanisms of resistance to panHER inhibitors in HER2+ breast cancer cells O Kutuk, H Basaga, Y Ozmay, B Karakas Annals of Oncology 28, v4, 2017 | | 2017 |
EXPLORING/DEFINING THE ROLE OF A NOVEL HOMOZYGOUS NONSENSECAST MUTATION IN A PLACK FAMILY SG Temel, B Karakas, H Saricaoglu, B Turkgenc, O Zorlu, O Kutuk, ... Erciyes Medical Journal 39 (2), S49-S49, 2017 | | 2017 |