Increased Wingless (Wnt) signaling in pituitary progenitor/stem cells gives rise to pituitary tumors in mice and humans C Gaston-Massuet, CL Andoniadou, M Signore, SA Jayakody, N Charolidi, ... Proceedings of the National Academy of Sciences 108 (28), 11482-11487, 2011 | 307 | 2011 |
Sox2+ stem/progenitor cells in the adult mouse pituitary support organ homeostasis and have tumor-inducing potential CL Andoniadou, D Matsushima, SNM Gharavy, M Signore, AI Mackintosh, ... Cell stem cell 13 (4), 433-445, 2013 | 298 | 2013 |
Identification of novel pathways involved in the pathogenesis of human adamantinomatous craniopharyngioma CL Andoniadou, C Gaston-Massuet, R Reddy, RP Schneider, MA Blasco, ... Acta neuropathologica 124, 259-271, 2012 | 184 | 2012 |
Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK … JR Apps, G Carreno, JM Gonzalez-Meljem, S Haston, R Guiho, ... Acta neuropathologica 135, 757-777, 2018 | 119 | 2018 |
SOX2 regulates the hypothalamic-pituitary axis at multiple levels SA Jayakody, CL Andoniadou, C Gaston-Massuet, M Signore, A Cariboni, ... The Journal of clinical investigation 122 (10), 3635-3646, 2012 | 106 | 2012 |
Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma JM Gonzalez-Meljem, S Haston, G Carreno, JR Apps, S Pozzi, C Stache, ... Nature communications 8 (1), 1819, 2017 | 101 | 2017 |
Sexual dimorphism in COVID-19: potential clinical and public health implications N Bechmann, A Barthel, A Schedl, S Herzig, Z Varga, C Gebhard, M Mayr, ... The Lancet Diabetes & Endocrinology 10 (3), 221-230, 2022 | 97 | 2022 |
Lack of the murine homeobox gene Hesx1 leads to a posterior transformation of the anterior forebrain CL Andoniadou, M Signore, E Sajedi, C Gaston-Massuet, D Kelberman, ... Oxford University Press for The Company of Biologists Limited 134 (8), 1499-1508, 2007 | 97 | 2007 |
MAPK pathway control of stem cell proliferation and differentiation in the embryonic pituitary provides insights into the pathogenesis of papillary craniopharyngioma S Haston, S Pozzi, G Carreno, S Manshaei, L Panousopoulos, ... Development 144 (12), 2141-2152, 2017 | 87 | 2017 |
CHD7 maintains neural stem cell quiescence and prevents premature stem cell depletion in the adult hippocampus KM Jones, N Sarić, JP Russell, CL Andoniadou, PJ Scambler, MA Basson Stem cells 33 (1), 196-210, 2015 | 87 | 2015 |
ARNT2 mutation causes hypopituitarism, post-natal microcephaly, visual and renal anomalies EA Webb, A AlMutair, D Kelberman, C Bacchelli, E Chanudet, F Lescai, ... Brain 136 (10), 3096-3105, 2013 | 83 | 2013 |
Genetic interaction between the homeobox transcription factors HESX1 and SIX3 is required for normal pituitary development C Gaston-Massuet, CL Andoniadou, M Signore, E Sajedi, S Bird, ... Developmental biology 324 (2), 322-333, 2008 | 74 | 2008 |
Developmental mechanisms directing early anterior forebrain specification in vertebrates CL Andoniadou, JP Martinez-Barbera Cellular and Molecular Life Sciences 70, 3739-3752, 2013 | 73 | 2013 |
Transcription factor 7-like 1 is involved in hypothalamo–pituitary axis development in mice and humans C Gaston-Massuet, MJ McCabe, V Scagliotti, RM Young, G Carreno, ... Proceedings of the National Academy of Sciences 113 (5), E548-E557, 2016 | 61 | 2016 |
HESX1-and TCF3-mediated repression of Wnt/β-catenin targets is required for normal development of the anterior forebrain CL Andoniadou, M Signore, RM Young, C Gaston-Massuet, SW Wilson, ... Development 138 (22), 4931-4942, 2011 | 60 | 2011 |
Hypothalamic sonic hedgehog is required for cell specification and proliferation of LHX3/LHX4 pituitary embryonic precursors G Carreno, JR Apps, EJ Lodge, L Panousopoulos, S Haston, ... Development 144 (18), 3289-3302, 2017 | 53 | 2017 |
Isolation and characterization of adrenocortical progenitors involved in the adaptation to stress C Steenblock, MF Rubin de Celis, LF Delgadillo Silva, V Pawolski, ... Proceedings of the National Academy of Sciences 115 (51), 12997-13002, 2018 | 52 | 2018 |
SOX2 haploinsufficiency is associated with slow progressing hypothalamo‐pituitary tumours KS Alatzoglou, CL Andoniadou, D Kelberman, CR Buchanan, J Crolla, ... Human mutation 32 (12), 1376-1380, 2011 | 52 | 2011 |
Single-cell molecular profiling of all three components of the HPA axis reveals adrenal ABCB1 as a regulator of stress adaptation JP Lopez, E Brivio, A Santambrogio, C De Donno, A Kos, M Peters, ... Science advances 7 (5), eabe4497, 2021 | 48 | 2021 |
Analysis of mouse models carrying the I26T and R160C substitutions in the transcriptional repressor HESX1 as models for septo-optic dysplasia and hypopituitarism E Sajedi, C Gaston-Massuet, M Signore, CL Andoniadou, D Kelberman, ... Disease models & mechanisms 1 (4-5), 241-254, 2008 | 48 | 2008 |