Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3 B Knuckley, CP Causey, JE Jones, M Bhatia, CJ Dreyton, TC Osborne, ... Biochemistry 49 (23), 4852-4863, 2010 | 189 | 2010 |
Protein arginine methyltransferase 1: positively charged residues in substrate peptides distal to the site of methylation are important for substrate binding and catalysis TC Osborne, O Obianyo, X Zhang, X Cheng, PR Thompson Biochemistry 46 (46), 13370-13381, 2007 | 151 | 2007 |
In situ generation of a bisubstrate analogue for protein arginine methyltransferase 1 T Osborne, RL Weller Roska, SR Rajski, PR Thompson Journal of the American Chemical Society 130 (14), 4574-4575, 2008 | 117 | 2008 |
Kinetic mechanism of protein arginine methyltransferase 1 O Obianyo, TC Osborne, PR Thompson Biochemistry 47 (39), 10420-10427, 2008 | 92 | 2008 |
A chloroacetamidine-based inactivator of protein arginine methyltransferase 1: design, synthesis, and in vitro and in vivo evaluation O Obianyo, CP Causey, T Osborne, JE Jones, YH Lee, MR Stallcup, ... Chembiochem: a European journal of chemical biology 11 (9), 1219, 2010 | 51 | 2010 |
Chloroacetamidine based inhibitors and activity based probes for the protein arginine methytransferases PR Thompson, TC Osborne, O Obianyo, CP Causey US Patent 8,323,918, 2012 | 31 | 2012 |
Survey of Chemistry II LibreTexts Remix T Osborne, DN Cannon-Rech University System of Georgia, 2022 | | 2022 |
Chloroacetamidine based inhibitors and activity based probes for the protein arginine methytransferases PR Thompson, TC Osborne, O Obianyo, CP Causey US Patent 8,569,005, 2013 | | 2013 |
Kinetic, mechanistic, and inhibition studies on the deiminase family of enzymes JE Jones University of South Carolina, 2010 | | 2010 |
Purification and characterization of PRMT4 and PRMT1 JR Burleyson University of South Carolina, 2009 | | 2009 |
Kinetic Characterization of Protein Arginine Methyltransferase 1 Aids the Development of PRMT-selective Bisubstrate Inhibitors TC Osborne ProQuest, 2008 | | 2008 |