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Mehtap Tugrak Sakarya, Assoc. Prof.Dr.
Mehtap Tugrak Sakarya, Assoc. Prof.Dr.
Faculty of Pharmacy,Tokat Gaziosmanpasa University, Department of pharmaceutical chemistry
Verified email at gop.edu.tr
Title
Cited by
Cited by
Year
Synthesis and bioactivity studies on new 4-(3-(4-Substitutedphenyl)-3a,4-dihydro-3H-indeno[1,2-c]pyrazol-2-yl) benzenesulfonamides
HI Gul, M Tugrak, H Sakagami, P Taslimi, I Gulcin, CT Supuran
Journal of Enzyme Inhibition and Medicinal Chemistry 31 (6), 1619-1624, 2016
1232016
New azafluorenones with cytotoxic and carbonic anhydrase inhibitory properties: 2-Aryl-4-(4-hydroxyphenyl)-5H-indeno [1, 2-b] pyridin-5-ones
M Tugrak, HI Gul, H Sakagami, I Gulcin, CT Supuran
Bioorganic chemistry 81, 433-439, 2018
622018
Synthesis of mono Mannich bases of 2-(4-hydroxybenzylidene)-2, 3-dihydroinden-1-one and evaluation of their cytotoxicities
M Tugrak, C Yamali, H Sakagami, HI Gul
Journal of Enzyme Inhibition and Medicinal Chemistry 31 (5), 818-823, 2016
582016
Synthesis and biological evaluation of some new mono Mannich bases with piperazines as possible anticancer agents and carbonic anhydrase inhibitors
M Tugrak, HI Gul, K Bandow, H Sakagami, I Gulcin, Y Ozkay, CT Supuran
Bioorganic Chemistry 90, 103095, 2019
572019
New phenolic Mannich bases with piperazines and their bioactivities
HI Gul, M Tugrak, M Gul, S Mazlumoglu, H Sakagami, I Gulcin, ...
Bioorganic chemistry 90, 103057, 2019
532019
The inhibitory effects of phenolic Mannich bases on carbonic anhydrase I and II isoenzymes
C Yamali, M Tugrak, HI Gul, M Tanc, CT Supuran
Journal of enzyme inhibition and medicinal chemistry 31 (6), 1678-1681, 2016
472016
Synthesis and in vitro carbonic anhydrases and acetylcholinesterase inhibitory activities of novel imidazolinone‐based benzenesulfonamides
M Tugrak, HI Gul, Y Demir, S Levent, I Gulcin
Archiv der Pharmazie 354 (4), 2000375, 2021
362021
Synthesis and anticancer properties of mono Mannich bases containing vanillin moiety
M Tugrak, HI Gul, H Sakagami, E Mete
Medicinal Chemistry Research 26, 1528-1534, 2017
242017
Synthesis of benzamide derivatives with thiourea‐substituted benzenesulfonamides as carbonic anhydrase inhibitors
M Tugrak, HI Gul, Y Demir, I Gulcin
Archiv Der Pharmazie 354 (2), 2000230, 2021
232021
Phenothiazine‐based chalcones as potential dual‐target inhibitors toward cholinesterases (AChE, BuChE) and monoamine oxidases (MAO‐A, MAO‐B)
C Yamali, FS Engin, S Bilginer, M Tugrak, D Ozmen Ozgun, G Ozli, ...
Journal of heterocyclic chemistry 58 (1), 161-171, 2021
202021
Synthesis of some acrylophenones with N-methylpiperazine and evaluation of their cytotoxicities
HI Gul, M Tugrak, H Sakagami
Journal of Enzyme Inhibition and Medicinal Chemistry 31 (1), 147-151, 2016
202016
Synthesis and cytotoxicities of 2-[4-hydroxy-(3, 5-bis-aminomethyl)-benzylidene]-indan-1-ones
M Tugrak, H Inci Gul, H Sakagami
Letters in Drug Design & Discovery 12 (10), 806-812, 2015
182015
Quinazolinone-based benzenesulfonamides with low toxicity and high affinity as monoamine oxidase-A inhibitors: Synthesis, biological evaluation and induced-fit docking studies
C Yamali, HI Gul, MT Sakarya, BN Saglik, A Ece, G Demirel, M Nenni, ...
Bioorganic Chemistry 124, 105822, 2022
172022
Investigation of solvent effect on photophysical properties of some sulfonamides derivatives 2
E BOZKURT, Hİ GÜL, M TUĞRAK
162017
Synthesis, cytotoxic, and carbonic anhydrase inhibitory effects of new 2‐(3‐(4‐methoxyphenyl)‐5‐(aryl)‐4,5‐dihydro‐1H‐pyrazol‐1‐yl)benzo[d]thiazole derivatives
M Tugrak, HI Gul, H Sakagami, I Gulcin
Journal of Heterocyclic Chemistry 57 (7), 2762-2768, 2020
152020
Synthesis and cytotoxicities of new azafluorenones with apoptotic mechanism of action and cell cycle analysis
HI Gul, M Tugrak, M Gul, H Sakagami, N Umemura, B Anil
Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2018
132018
Acetylcholinesterase inhibitory potencies of new pyrazoline derivatives
M Tuğrak, Hİ Gül, İ Gülçin
Journal of Research in Pharmacy 24 (4), 464-471, 2020
102020
Synthesis and pharmacological effects of novel benzenesulfonamides carryingbenzamide moiety as carbonic anhydrase and acetylcholinesterase inhibitors
M Tuğrak, Hİ GÜl, B ANIL, İ GÜlÇİn
Turkish Journal of Chemistry 44 (6), 1601-1609, 2020
102020
New chalcone derivatives with pyrazole and sulfonamide pharmacophores as carbonic anhydrase inhibitors
M Tugrak, HI Gul, H Akincioglu, I Gulcin
Letters in Drug Design & Discovery 18 (2), 191-198, 2021
92021
Synthesis and biological evaluation of new pyrazolebenzene-sulphonamides as potentialanticancer agents and hCA I and II inhibitors
M Tuğrak, Hİ Gül, H Sakagami, R Kaya, İ Gülçin
Turkish Journal of Chemistry 45 (3), 528-539, 2021
62021
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