Functional role of the β subunit of high conductance calcium-activated potassium channels OB McManus, LMH Helms, L Pallanck, B Ganetzky, R Swanson, ... Neuron 14 (3), 645-650, 1995 | 554 | 1995 |
Evidence that the M2 membrane-spanning region lines the ion channel pore of the nicotinic receptor RJ Leonard, CG Labarca, P Charnet, N Davidson, HA Lester Science 242 (4885), 1578-1581, 1988 | 425 | 1988 |
Purification, characterization, and biosynthesis of margatoxin, a component of Centruroides margaritatus venom that selectively inhibits voltage-dependent potassium channels. M Garcia-Calvo, RJ Leonard, J Novick, SP Stevens, W Schmalhofer, ... Journal of Biological Chemistry 268 (25), 18866-18874, 1993 | 408 | 1993 |
High-conductance calcium-activated potassium channels; structure, pharmacology, and function GJ Kaczorowski, HG Knaus, RJ Leonard, OB McManus, ML Garcia Journal of bioenergetics and biomembranes 28, 255-267, 1996 | 376 | 1996 |
Selective blockers of voltage-gated K+ channels depolarize human T lymphocytes: mechanism of the antiproliferative effect of charybdotoxin. RJ Leonard, ML Garcia, RS Slaughter, JP Reuben Proceedings of the National Academy of Sciences 89 (21), 10094-10098, 1992 | 327 | 1992 |
An open-channel blocker interacts with adjacent turns of α-helices in the nicotinic acetylcholine receptor P Charnet, C Labarca, RJ Leonard, NJ Vogelaar, L Czyzyk, A Gouin, ... Neuron 4 (1), 87-95, 1990 | 310 | 1990 |
Acetylcholine raises excitability by inhibiting the fast transient potassium current in cultured hippocampal neurons. Y Nakajima, S Nakajima, RJ Leonard, K Yamaguchi Proceedings of the National Academy of Sciences 83 (9), 3022-3026, 1986 | 208 | 1986 |
Growth hormone secretagogue receptor family members and ligands RG Smith, R Leonard, ART Bailey, O Palyha, S Feighner, C Tan, ... Endocrine 14, 9-14, 2001 | 192 | 2001 |
Modulation of pulsatile GH release through a novel receptor in hypothalamus and pituitary gland. RG Smith, SS Pong, G Hickey, T Jacks, K Cheng, R Leonard, CJ Cohen, ... Recent Progress in Hormone Research 51, 261-85; discussion 285, 1996 | 171 | 1996 |
Synthetic charybdotoxin-iberiotoxin chimeric peptides define toxin binding sites on calcium-activated and voltage-dependent potassium channels KM Giangiacomo, EE Sugg, M Garcia-Calvo, RJ Leonard, OB McManus, ... Biochemistry 32 (9), 2363-2370, 1993 | 96 | 1993 |
Adenosine: a partial agonist of the growth hormone secretagogue receptor RG Smith, PR Griffin, Y Xu, AGA Smith, K Liu, J Calacay, SD Feighner, ... Biochemical and biophysical research communications 276 (3), 1306-1313, 2000 | 79 | 2000 |
Margatoxin Binds to a Homomultimer of KV1.3 Channels in Jurkat Cells. Comparison with KV1.3 Expressed in CHO Cells LMH Helms, JP Felix, RM Bugianesi, ML Garcia, S Stevens, RJ Leonard, ... Biochemistry 36 (12), 3737-3744, 1997 | 64 | 1997 |
Chemical synthesis and structure-function studies of margatoxin, a potent inhibitor of voltage-dependent potassium channel in human T lymphocytes MA Bednarek, RM Bugianesi, RJ Leonard, JP Felix Biochemical and biophysical research communications 198 (2), 619-625, 1994 | 59 | 1994 |
Differential development of two classes of acetylcholine receptors in Xenopus muscle in culture RJ Leonard, S Nakajima, Y Nakajima, T Takahashi Science 226 (4670), 55-57, 1984 | 47 | 1984 |
Expression of Drosophila Shaker potassium channels in mammalian cells infected with recombinant vaccinia virus. RJ Leonard, A Karschin, S Jayashree-Aiyar, N Davidson, MA Tanouye, ... Proceedings of the National Academy of Sciences 86 (19), 7629-7633, 1989 | 40 | 1989 |
Mechanism of action of GHRP-6 and nonpeptidyl growth hormone secretagogues RG Smith, K Cheng, SS Pong, R Leonard, CJ Cohen, JP Arena, ... Growth hormone secretagogues, 147-163, 1996 | 33 | 1996 |
Light modulates voltage-dependent potassium channels in Limulus ventral photoreceptors RJ Leonard, JE Lisman Science 212 (4500), 1273-1275, 1981 | 33 | 1981 |
Scorpion peptide margatoxin with immunosuppressant activity ML Garcia, GC Koo, RJ Leonard, CCS Lin, RS Slaughter, SP Stevens, ... US Patent 5,494,895, 1996 | 29 | 1996 |
Reverse pharmacology of the nicotinic acetylcholine receptor. Mapping the local anesthetic binding site. RJ Leonard, P Charnet, C Labarca, NJ Vogelaar, L Czyzyk, A Gouin, ... Annals of the New York Academy of Sciences 625, 588-599, 1991 | 27 | 1991 |
Stable expression of human Kv1. 3 potassium channels resets the resting membrane potential of cultured mammalian cells FP Defarias, SP Stevens, RJ Leonard Receptors & channels 3 (4), 273-281, 1995 | 23 | 1995 |