| Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia V Quesada, L Conde, N Villamor, GR Ordóñez, P Jares, L Bassaganyas, ... Nature genetics 44 (1), 47-52, 2012 | 1234 | 2012 |
| POT1 loss-of-function variants predispose to familial melanoma CD Robles-Espinoza, M Harland, AJ Ramsay, LG Aoude, V Quesada, ... Nature genetics 46 (5), 478-481, 2014 | 420 | 2014 |
| POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia AJ Ramsay, V Quesada, M Foronda, L Conde, A Martínez-Trillos, ... Nature genetics 45 (5), 526-530, 2013 | 329 | 2013 |
| Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response FG Osorio, C Bárcena, C Soria-Valles, AJ Ramsay, F de Carlos, J Cobo, ... Genes & development 26 (20), 2311-2324, 2012 | 300 | 2012 |
| Aging and chronic DNA damage response activate a regulatory pathway involving miR‐29 and p53 AP Ugalde, AJ Ramsay, J De La Rosa, I Varela, G Mariño, J Cadiñanos, ... The EMBO journal 30 (11), 2219-2232, 2011 | 274 | 2011 |
| Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in mice PM Quirós, AJ Ramsay, D Sala, E Fernández‐Vizarra, F Rodríguez, ... The EMBO journal 31 (9), 2117-2133, 2012 | 269 | 2012 |
| Nonsense Mutations in the Shelterin Complex Genes ACD and TERF2IP in Familial Melanoma LG Aoude, AL Pritchard, CD Robles-Espinoza, K Wadt, M Harland, J Choi, ... Journal of the National Cancer Institute 107 (2), dju408, 2015 | 188 | 2015 |
| Kallikrein-related peptidase 4 (KLK4) initiates intracellular signaling via protease-activated receptors (PARs): KLK4 and PAR-2 are co-expressed during prostate cancer progression AJ Ramsay, Y Dong, ML Hunt, ML Linn, H Samaratunga, JA Clements, ... Journal of Biological Chemistry 283 (18), 12293-12304, 2008 | 165 | 2008 |
| STEROID DIABETES IN GUINEA PIGS EFFECTS OF CORTISONE ADMINISTRATION ON BLOOD-AND URINARY GLUCOSE, NITROGEN EXCRETION, FAT DEPOSITION, AND THE ISLETS OF LANGERHANS FX HAUSBERGER, AJ RAMSAY Endocrinology 53 (4), 423-435, 1953 | 159 | 1953 |
| Matriptase-2 (TMPRSS6): a proteolytic regulator of iron homeostasis AJ Ramsay, JD Hooper, AR Folgueras, G Velasco, C López-Otín haematologica 94 (6), 840, 2009 | 145 | 2009 |
| Steroid diabetes in guinea pigs: effects of hydrocortisone administration on blood and urinary glucose, nitrogen excretion, fat deposition, and the islets of Langerhans FX HAUSBERGER, AJ RAMSAY Endocrinology 56 (5), 533-540, 1955 | 123 | 1955 |
| Islet hypertrophy in obesity of mice bearing ACTH-secreting tumors FX HAUSBERGER, AJ RAMSAY Endocrinology 65 (2), 165-171, 1959 | 110 | 1959 |
| Cell–cell adhesion genes CTNNA2 and CTNNA3 are tumour suppressors frequently mutated in laryngeal carcinomas M Fanjul-Fernández, V Quesada, R Cabanillas, J Cadiñanos, T Fontanil, ... Nature communications 4 (1), 2531, 2013 | 89 | 2013 |
| Matriptase-2 mutations in iron-refractory iron deficiency anemia patients provide new insights into protease activation mechanisms AJ Ramsay, V Quesada, M Sanchez, C Garabaya, MP Sardà, M Baiget, ... Human molecular genetics 18 (19), 3673-3683, 2009 | 81 | 2009 |
| Chronic Lymphocytic Leukemia with SF3B1 Mutation V Quesada, AJ Ramsay, C Lopez-Otin New England Journal of Medicine 366 (26), 2530-2530, 2012 | 75 | 2012 |
| Mutations in CHD2 cause defective association with active chromatin in chronic lymphocytic leukemia D Rodríguez, G Bretones, V Quesada, N Villamor, JR Arango, ... Blood, The Journal of the American Society of Hematology 126 (2), 195-202, 2015 | 69 | 2015 |
| The type II transmembrane serine protease matriptase-2-identification, structural features, enzymology, expression pattern and potential roles A Ramsay, J Reid, G Velasco, J Quigley, J Hooper Frontiers in Bioscience-Landmark 13 (2), 569-579, 2008 | 66 | 2008 |
| The genomic landscape of chronic lymphocytic leukemia: clinical implications V Quesada, AJ Ramsay, D Rodríguez, XS Puente, E Campo, ... BMC medicine 11, 1-8, 2013 | 53 | 2013 |
| Prostatic trypsin-like kallikrein-related peptidases (KLKs) and other prostate-expressed tryptic proteinases as regulators of signalling via proteinase-activated receptors (PARs) AJ Ramsay, JC Reid, MN Adams, H Samaratunga, Y Dong, JA Clements, ... Walter de Gruyter 389 (6), 653-668, 2008 | 51 | 2008 |
| Iron-deficiency anemia from matriptase-2 inactivation is dependent on the presence of functional Bmp6 A Lenoir, JC Deschemin, L Kautz, AJ Ramsay, MP Roth, C Lopez-Otin, ... Blood, The Journal of the American Society of Hematology 117 (2), 647-650, 2011 | 50 | 2011 |
