p38α MAPK pathway: A key factor in colorectal cancer therapy and chemoresistance V Grossi, A Peserico, T Tezil, C Simone World journal of gastroenterology: WJG 20 (29), 9744, 2014 | 243 | 2014 |
Small inhibitor of Bcl-2, HA14-1, selectively enhanced the apoptotic effect of cisplatin by modulating Bcl-2 family members in MDA-MB-231 breast cancer cells ED Arisan, O Kutuk, T Tezil, C Bodur, D Telci, H Basaga Breast cancer research and treatment 119, 271-281, 2010 | 72 | 2010 |
The longevity SNP rs2802292 uncovered: HSF1 activates stress-dependent expression of FOXO3 through an intronic enhancer V Grossi, G Forte, P Sanese, A Peserico, T Tezil, M Lepore Signorile, ... Nucleic Acids Research 46 (11), 5587-5600, 2018 | 66 | 2018 |
Cisplatin overcomes Bcl-2-mediated resistance to apoptosis via preferential engagement of Bak: critical role of Noxa-mediated lipid peroxidation O Kutuk, ED Arisan, T Tezil, MC Shoshan, H Basaga Carcinogenesis 30 (9), 1517-1527, 2009 | 60 | 2009 |
Targeted therapy against chemoresistant colorectal cancers: Inhibition of p38α modulates the effect of cisplatin in vitro and in vivo through the tumor suppressor FoxO3A A Germani, A Matrone, V Grossi, A Peserico, P Sanese, M Liuzzi, ... Cancer letters 344 (1), 110-118, 2014 | 52 | 2014 |
Inactivation of Bcl‐2 through IκB kinase (IKK)‐dependent phosphorylation mediates apoptosis upon exposure to 4‐hydroxynonenal (HNE) C Bodur, O Kutuk, T Tezil, H Basaga Journal of cellular physiology 227 (11), 3556-3565, 2012 | 38 | 2012 |
Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy V Celestini, T Tezil, L Russo, C Fasano, P Sanese, G Forte, A Peserico, ... Cell Death & Disease 9 (2), 231, 2018 | 36 | 2018 |
Lifespan-increasing drug nordihydroguaiaretic acid inhibits p300 and activates autophagy T Tezil, M Chamoli, CP Ng, RP Simon, VJ Butler, M Jung, J Andersen, ... npj Aging and Mechanisms of Disease 5 (1), 7, 2019 | 25 | 2019 |
IKK-β mediates chemoresistance by sequestering FOXO3; a critical factor for cell survival and death T Tezil, C Bodur, O Kutuk, H Basaga Cellular signalling 24 (6), 1361-1368, 2012 | 25 | 2012 |
AMP‐activated protein kinase couples 3‐bromopyruvate‐induced energy depletion to apoptosis via activation of FoxO3a and upregulation of proapoptotic Bcl‐2 proteins C Bodur, B Karakas, AC Timucin, T Tezil, H Basaga Molecular Carcinogenesis 55 (11), 1584-1597, 2016 | 24 | 2016 |
Modulation of cell death in age-related diseases T Tezil, H Basaga Current pharmaceutical design 20 (18), 3052-3067, 2014 | 22 | 2014 |
FOXO1 promotes HIV latency by suppressing ER stress in T cells A Vallejo-Gracia, IP Chen, R Perrone, E Besnard, D Boehm, E Battivelli, ... Nature microbiology 5 (9), 1144-1157, 2020 | 17 | 2020 |
Defining metabolic and nonmetabolic regulation of histone acetylation by NSAID chemotypes JH Shrimp, JM Garlick, T Tezil, AW Sorum, AJ Worth, IA Blair, E Verdin, ... Molecular pharmaceutics 15 (3), 729-736, 2017 | 6 | 2017 |
T cell stimulation remodels the latently HIV-1 infected cell population by differential activation of proviral chromatin B Lindqvist, BB Jütte, L Love, W Assi, J Roux, A Sönnerborg, T Tezil, ... PLoS Pathogens 18 (6), e1010555, 2022 | 5 | 2022 |
Lifespan-increasing drug nordihydroguaiaretic acid inhibits p300 and activates T Tezil, M Chamoli, CP Ng NPJ aging and mechanisms of disease, 5 (1), 2019 | | 2019 |
PO-243 Uncoupling FOXO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy C Simone, V Celestini, T Tezil, L Russo, C Fasano, P Sanese, G Forte, ... ESMO Open 3, A115, 2018 | | 2018 |
PO-161 The AMPK and MEK/ERK signalling pathways regulate mitochondrial FOXO3A import through phosphorylation of serine 12 and serine 30 V Celestini, T Tezil, L Russo, C Fasano, P Sanese, G Forte, A Peserico, ... ESMO Open 3, A289-A290, 2018 | | 2018 |
MODULATION OF P300 FUNCTION IMPROVES HEALTHSPAN AND LIFESPAN IN C. ELEGANS T Tezil, C Ng, E Verdin Innovation in Aging 1 (Suppl 1), 1223, 2017 | | 2017 |
Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy C Simone, V Celestini, T Tezil, L Russo, C Fasano, P Sanese, G Forte, ... Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells …, 2017 | | 2017 |
Deciphering the Mitochondrial Tail of FoxO3A Code T Tezil, L Russo, C Fasano, G Forte, V Grossi, P Sanese, D De Rasmo, ... Deciphering the Mitochondrial Tail of FoxO3A Code, 2016 | | 2016 |