Follow
Christopher  B Phelps
Christopher B Phelps
Nurix Therapeutics
Verified email at gsk.com
Title
Cited by
Cited by
Year
The ankyrin repeats of TRPV1 bind multiple ligands and modulate channel sensitivity
PV Lishko, E Procko, X Jin, CB Phelps, R Gaudet
Neuron 54 (6), 905-918, 2007
5452007
Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C
G Landouré, AA Zdebik, TL Martinez, BG Burnett, HC Stanescu, H Inada, ...
Nature genetics 42 (2), 170-174, 2010
3572010
Differential regulation of TRPV1, TRPV3, and TRPV4 sensitivity through a conserved binding site on the ankyrin repeat domain
CB Phelps, RR Wang, SS Choo, R Gaudet
Journal of Biological Chemistry 285 (1), 731-740, 2010
2062010
Mechanism of κB DNA binding by Rel/NF-κB dimers
CB Phelps, LL Sengchanthalangsy, S Malek, G Ghosh
Journal of Biological Chemistry 275 (32), 24392-24399, 2000
1762000
Structural Analyses of the Ankyrin Repeat Domain of TRPV6 and Related TRPV Ion Channels,
CB Phelps, RJ Huang, PV Lishko, RR Wang, R Gaudet
Biochemistry 47 (8), 2476-2484, 2008
1472008
Mechanism of IκBα binding to NF-κB dimers
CB Phelps, LL Sengchanthalangsy, T Huxford, G Ghosh
Journal of Biological Chemistry 275 (38), 29840-29846, 2000
1462000
X-ray crystal structure of proto-oncogene product c-Rel bound to the CD28 response element of IL-2
DB Huang, YQ Chen, M Ruetsche, CB Phelps, G Ghosh
Structure 9 (8), 669-678, 2001
1122001
The role of the N terminus and transmembrane domain of TRPM8 in channel localization and tetramerization
CB Phelps, R Gaudet
Journal of Biological Chemistry 282 (50), 36474-36480, 2007
1092007
Ruthenium promoted on-DNA ring-closing metathesis and cross-metathesis
X Lu, L Fan, CB Phelps, CP Davie, CP Donahue
Bioconjugate Chemistry 28 (6), 1625-1629, 2017
762017
Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening
CA Machutta, CS Kollmann, KE Lind, X Bai, PF Chan, J Huang, L Ballell, ...
Nature communications 8 (1), 16081, 2017
732017
Construction, expression, purification and functional analysis of recombinant NFκB p50/p65 heterodimer
FE Chen, S Kempiak, DB Huang, C Phelps, G Ghosh
Protein engineering 12 (5), 423-428, 1999
731999
Crystal structure of a free κB DNA: insights into DNA recognition by transcription factor NF-κB
DB Huang, CB Phelps, AJ Fusco, G Ghosh
Journal of molecular biology 346 (1), 147-160, 2005
642005
Differential binding of cAMP-dependent protein kinase regulatory subunit isoforms Iα and IIβ to the catalytic subunit
X Cheng, C Phelps, SS Taylor
Journal of Biological Chemistry 276 (6), 4102-4108, 2001
612001
Solvent exposed non-contacting amino acids play a critical role in NF-κB/IκBα complex formation
T Huxford, D Mishler, CB Phelps, DB Huang, LL Sengchanthalangsy, ...
Journal of molecular biology 324 (4), 587-597, 2002
392002
Insights into the roles of conserved and divergent residues in the ankyrin repeats of TRPV ion channels
CB Phelps, E Procko, PV Lishko, RR Wang, R Gaudet
Channels 1 (3), 148-151, 2007
312007
Integration of lead discovery tactics and the evolution of the lead discovery toolbox
M Leveridge, CW Chung, JW Gross, CB Phelps, D Green
SLAS DISCOVERY: Advancing Life Sciences R&D 23 (9), 881-897, 2018
302018
Development of a selection method for discovering irreversible (covalent) binders from a DNA-encoded library
Z Zhu, LSC Grady, Y Ding, KE Lind, CP Davie, CB Phelps, G Evindar
SLAS DISCOVERY: Advancing the Science of Drug Discovery 24 (2), 169-174, 2019
192019
Discreet mutations from c-Rel to v-Rel alter κB DNA recognition, IκBα binding, and dimerization: implications for v-Rel oncogenicity
CB Phelps, G Ghosh
Oncogene 23 (6), 1229-1238, 2004
152004
Discovery of Proline-Based p300/CBP Inhibitors Using DNA-Encoded Library Technology in Combination with High-Throughput Screening
X Tian, D Suarez, D Thomson, W Li, EA King, L LaFrance, J Boehm, ...
Journal of Medicinal Chemistry 65 (21), 14391-14408, 2022
72022
DNA-Encoded Library Technology (ELT)
G Yao, X Lu, C Phelps, G Evindar
22018
The system can't perform the operation now. Try again later.
Articles 1–20