| Interferon-γ and tumor necrosis factor-α synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression F Wang, WV Graham, Y Wang, ED Witkowski, BT Schwarz, JR Turner The American journal of pathology 166 (2), 409-419, 2005 | 797 | 2005 |
| Epithelial barriers in homeostasis and disease AM Marchiando, WV Graham, JR Turner Annual Review of Pathology: Mechanisms of Disease 5, 119-144, 2010 | 692 | 2010 |
| Update on Alzheimer's disease therapy and prevention strategies WV Graham, A Bonito-Oliva, TP Sakmar Annual review of medicine 68, 413-430, 2017 | 555 | 2017 |
| Caveolin-1–dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo AM Marchiando, L Shen, WV Graham, CR Weber, BT Schwarz, JR Austin, ... Journal of Cell Biology 189 (1), 111-126, 2010 | 474 | 2010 |
| IFN-γ-induced TNFR2 expression is required for TNF-dependent intestinal epithelial barrier dysfunction F Wang, BT Schwarz, WV Graham, Y Wang, L Su, DR Clayburgh, ... Gastroenterology 131 (4), 1153-1163, 2006 | 345 | 2006 |
| The epithelial barrier is maintained by in vivo tight junction expansion during pathologic intestinal epithelial shedding AM Marchiando, L Shen, WV Graham, KL Edelblum, CA Duckworth, ... Gastroenterology 140 (4), 1208-1218. e2, 2011 | 296 | 2011 |
| Tumor necrosis factor-induced long myosin light chain kinase transcription is regulated by differentiation-dependent signaling events: characterization of the human long myosin … WV Graham, F Wang, DR Clayburgh, JX Cheng, B Yoon, Y Wang, A Lin, ... Journal of Biological Chemistry 281 (36), 26205-26215, 2006 | 151 | 2006 |
| Distinct temporal-spatial roles for rho kinase and myosin light chain kinase in epithelial purse-string wound closure JM Russo, P Florian, LE Shen, WV Graham, MS Tretiakova, AH Gitter, ... Gastroenterology 128 (4), 987-1001, 2005 | 141 | 2005 |
| The prognosis of chronic active hepatitis without cirrhosis in relation to bridging necrosis W Graham, E Cooksley, RA Bradbear, W Robinson, M Harrison, ... Hepatology 6 (3), 345-348, 1986 | 139 | 1986 |
| Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis WV Graham, W He, AM Marchiando, J Zha, G Singh, HS Li, A Biswas, ... Nature medicine 25 (4), 690-700, 2019 | 117 | 2019 |
| A combined in vitro/bioinformatic investigation of redox regulatory mechanisms governing cell cycle progression JE Conour, WV Graham, HR Gaskins Physiological Genomics 18 (2), 196-205, 2004 | 111 | 2004 |
| Loss of somatic heterozygosity in hepatocellular carcinoma GJ Walker, NK Hayward, S Falvey, W Graham, E Cooksley Cancer research 51 (16), 4367-4370, 1991 | 106 | 1991 |
| Gastrointestinal and microbial responses to sulfate-supplemented drinking water in mice B Deplancke, K Finster, WV Graham, CT Collier, JE Thurmond, ... Experimental biology and medicine 228 (4), 424-433, 2003 | 98 | 2003 |
| Contributions of myosin light chain kinase to regulation of epithelial paracellular permeability and mucosal homeostasis WQ He, J Wang, JY Sheng, JM Zha, WV Graham, JR Turner International journal of molecular sciences 21 (3), 993, 2020 | 92 | 2020 |
| Hepatocellular carcinoma mutation. NK Hayward, GJ Walker, W Graham, E Cooksley | 81 | 1991 |
| Notch1 promotes survival of E2A-deficient T cell lymphomas through pre–T cell receptor–dependent and –independent mechanisms EJ Reschly, C Spaulding, T Vilimas, WV Graham, RL Brumbaugh, ... Blood 107 (10), 4115-4121, 2006 | 70 | 2006 |
| MAPKAPK-2 is a critical signaling intermediate in NHE3 activation following Na+-glucose cotransport Z Hu, Y Wang, WV Graham, L Su, MW Musch, JR Turner Journal of biological chemistry 281 (34), 24247-24253, 2006 | 55 | 2006 |
| A strategy to identify stable membrane-permeant peptide inhibitors of myosin light chain kinase SE Owens, WV Graham, D Siccardi, JR Turner, RJ Mrsny Pharmaceutical research 22, 703-709, 2005 | 49 | 2005 |
| Nucleobindin 1 binds to multiple types of pre-fibrillar amyloid and inhibits fibrillization A Bonito-Oliva, S Barbash, TP Sakmar, WV Graham Scientific reports 7 (1), 42880, 2017 | 39 | 2017 |
| Sustained virologic response (SVR) resulting from treatment with peginterferon alfa-2a (40KD)(Pegasys (R)) alone or in combination with ribavirin (Copegus (R)) is durable and … MG Swain, MY Lai, ML Shiffman, W Graham, E Cooksley, A Abergel, A Lin, ... Gastroenterology 132 (4), A741-A741, 2007 | 18 | 2007 |
