Application of high-dimensional feature selection: evaluation for genomic prediction in man ML Bermingham, R Pong-Wong, A Spiliopoulou, C Hayward, I Rudan, ... Scientific reports 5 (1), 10312, 2015 | 398 | 2015 |
Genome-wide association study of diabetic kidney disease highlights biology involved in glomerular basement membrane collagen RM Salem, JN Todd, N Sandholm, JB Cole, WM Chen, D Andrews, ... Journal of the American Society of Nephrology 30 (10), 2000-2016, 2019 | 154 | 2019 |
Genetically determined serum urate levels and cardiovascular and other diseases in UK Biobank cohort: A phenome-wide mendelian randomization study X Li, X Meng, Y He, A Spiliopoulou, M Timofeeva, WQ Wei, A Gifford, ... PLoS medicine 16 (10), e1002937, 2019 | 100 | 2019 |
GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk N Pirastu, PK Joshi, PS De Vries, MC Cornelis, PM McKeigue, NN Keum, ... Nature communications 8 (1), 1584, 2017 | 84 | 2017 |
Exploring causality in the association between circulating 25-hydroxyvitamin D and colorectal cancer risk: a large Mendelian randomisation study Y He, M Timofeeva, SM Farrington, P Vaughan-Shaw, V Svinti, M Walker, ... BMC medicine 16, 1-11, 2018 | 80 | 2018 |
MR-PheWAS: exploring the causal effect of SUA level on multiple disease outcomes by using genetic instruments in UK Biobank X Li, X Meng, A Spiliopoulou, M Timofeeva, WQ Wei, A Gifford, X Shen, ... Annals of the rheumatic diseases 77 (7), 1039-1047, 2018 | 73 | 2018 |
Phenome-wide Mendelian-randomization study of genetically determined vitamin D on multiple health outcomes using the UK Biobank study X Meng, X Li, MN Timofeeva, Y He, A Spiliopoulou, WQ Wei, A Gifford, ... International journal of epidemiology 48 (5), 1425-1434, 2019 | 68 | 2019 |
Genome-wide association study of response to methotrexate in early rheumatoid arthritis patients JC Taylor, T Bongartz, J Massey, B Mifsud, A Spiliopoulou, IC Scott, ... The pharmacogenomics journal 18 (4), 528-538, 2018 | 54 | 2018 |
Validity of a two-component imaging-derived disease activity score for improved assessment of synovitis in early rheumatoid arthritis EMA Hensor, P McKeigue, SF Ling, M Colombo, JH Barrett, JL Nam, ... Rheumatology 58 (8), 1400-1409, 2019 | 52 | 2019 |
Genome-wide association study of response to tumour necrosis factor inhibitor therapy in rheumatoid arthritis J Massey, D Plant, K Hyrich, AW Morgan, AG Wilson, A Spiliopoulou, ... The pharmacogenomics journal 18 (5), 657-664, 2018 | 52 | 2018 |
Persistent C-peptide secretion in type 1 diabetes and its relationship to the genetic architecture of diabetes PM McKeigue, A Spiliopoulou, S McGurnaghan, M Colombo, ... BMC medicine 17, 1-11, 2019 | 49 | 2019 |
Genome‐Wide association study of NAFLD using electronic health records CJ Fairfield, TM Drake, R Pius, AD Bretherick, A Campbell, DW Clark, ... Hepatology communications 6 (2), 297-308, 2022 | 44 | 2022 |
GeneImp: fast imputation to large reference panels using genotype likelihoods from ultralow coverage sequencing A Spiliopoulou, M Colombo, P Orchard, F Agakov, P McKeigue Genetics 206 (1), 91-104, 2017 | 38 | 2017 |
Genomic prediction of complex human traits: relatedness, trait architecture and predictive meta-models A Spiliopoulou, R Nagy, ML Bermingham, JE Huffman, C Hayward, ... Human molecular genetics 24 (14), 4167-4182, 2015 | 38 | 2015 |
Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for CD40 and CD39 A Spiliopoulou, M Colombo, D Plant, N Nair, J Cui, MJH Coenen, K Ikari, ... Annals of the rheumatic diseases 78 (8), 1055-1061, 2019 | 30 | 2019 |
Genome‐wide analysis identifies gallstone‐susceptibility loci including genes regulating gastrointestinal motility CJ Fairfield, TM Drake, R Pius, AD Bretherick, A Campbell, DW Clark, ... Hepatology 75 (5), 1081-1094, 2022 | 22 | 2022 |
Prediction of colorectal cancer risk based on profiling with common genetic variants X Li, M Timofeeva, A Spiliopoulou, P McKeigue, Y He, X Zhang, V Svinti, ... International journal of cancer 147 (12), 3431-3437, 2020 | 22 | 2020 |
Mendelian randomization and clinical trial evidence supports TYK2 inhibition as a therapeutic target for autoimmune diseases S Yuan, L Wang, H Zhang, F Xu, X Zhou, L Yu, J Sun, J Chen, H Ying, ... EBioMedicine 89, 2023 | 19 | 2023 |
Prediction of treatment response in rheumatoid arthritis patients using genome‐wide SNP data S Cherlin, D Plant, JC Taylor, M Colombo, A Spiliopoulou, E Tzanis, ... Genetic Epidemiology 42 (8), 754-771, 2018 | 19 | 2018 |
Comparing probabilistic models for melodic sequences A Spiliopoulou, A Storkey Machine Learning and Knowledge Discovery in Databases: European Conference …, 2011 | 18 | 2011 |