| Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein R Sattler, Z Xiong, WY Lu, M Hafner, JF MacDonald, M Tymianski Science 284 (5421), 1845-1848, 1999 | 1092 | 1999 |
| The C9orf72 repeat expansion disrupts nucleocytoplasmic transport K Zhang, CJ Donnelly, AR Haeusler, JC Grima, JB Machamer, ... Nature 525 (7567), 56-61, 2015 | 1018 | 2015 |
| RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention CJ Donnelly, PW Zhang, JT Pham, AR Haeusler, NA Mistry, S Vidensky, ... Neuron 80 (2), 415-428, 2013 | 1007 | 2013 |
| C9orf72 nucleotide repeat structures initiate molecular cascades of disease AR Haeusler, CJ Donnelly, G Periz, EAJ Simko, PG Shaw, MS Kim, ... Nature 507 (7491), 195-200, 2014 | 999 | 2014 |
| Molecular mechanisms of glutamate receptor-mediated excitotoxic neuronal cell death R Sattler, M Tymianski Molecular neurobiology 24, 107-129, 2001 | 735 | 2001 |
| Molecular mechanisms of calcium-dependent excitotoxicity R Sattler, M Tymianski Journal of molecular medicine 78, 3-13, 2000 | 647 | 2000 |
| TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD CC Chou, YI Zhang, ME Umoh, SW Vaughan, I Lorenzini, F Liu, ... Nature neuroscience 21 (2), 228-239, 2018 | 490 | 2018 |
| The neuronal Rho-GEF kalirin-7 interacts with PDZ domain–containing proteins and regulates dendritic morphogenesis P Penzes, RC Johnson, R Sattler, X Zhang, RL Huganir, V Kambampati, ... Neuron 29 (1), 229-242, 2001 | 459 | 2001 |
| Distinct influx pathways, not calcium load, determine neuronal vulnerability to calcium neurotoxicity R Sattler, MP Charlton, M Hafner, M Tymianski Journal of neurochemistry 71 (6), 2349-2364, 1998 | 357 | 1998 |
| Distinct roles of synaptic and extrasynaptic NMDA receptors in excitotoxicity R Sattler, Z Xiong, WY Lu, JF MacDonald, M Tymianski Journal of Neuroscience 20 (1), 22-33, 2000 | 313 | 2000 |
| Human stem cell-derived spinal cord astrocytes with defined mature or reactive phenotypes L Roybon, NJ Lamas, A Garcia-Diaz, EJ Yang, R Sattler, V Jackson-Lewis, ... Cell reports 4 (5), 1035-1048, 2013 | 232 | 2013 |
| Artificial intelligence in neurodegenerative disease research: use of IBM Watson to identify additional RNA-binding proteins altered in amyotrophic lateral sclerosis N Bakkar, T Kovalik, I Lorenzini, S Spangler, A Lacoste, K Sponaugle, ... Acta neuropathologica 135, 227-247, 2018 | 170 | 2018 |
| Regulation and dysregulation of glutamate transporters R Sattler, JD Rothstein Neurotransmitter Transporters, 277-303, 2006 | 162 | 2006 |
| Persistent hippocampal CA1 LTP in mice lacking the C-terminal PDZ ligand of GluR1 CH Kim, K Takamiya, RS Petralia, R Sattler, S Yu, W Zhou, R Kalb, ... Nature neuroscience 8 (8), 985-987, 2005 | 120 | 2005 |
| Harmine, a natural beta-carboline alkaloid, upregulates astroglial glutamate transporter expression Y Li, R Sattler, EJ Yang, A Nunes, Y Ayukawa, S Akhtar, G Ji, PW Zhang, ... Neuropharmacology 60 (7-8), 1168-1175, 2011 | 98 | 2011 |
| Post-transcriptional inhibition of Hsc70-4/HSPA8 expression leads to synaptic vesicle cycling defects in multiple models of ALS AN Coyne, I Lorenzini, CC Chou, M Torvund, RS Rogers, A Starr, ... Cell reports 21 (1), 110-125, 2017 | 96 | 2017 |
| Glycolysis upregulation is neuroprotective as a compensatory mechanism in ALS E Manzo, I Lorenzini, D Barrameda, AG O'Conner, JM Barrows, A Starr, ... Elife 8, e45114, 2019 | 91 | 2019 |
| C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation D Lall, I Lorenzini, TA Mota, S Bell, TE Mahan, JD Ulrich, H Davtyan, ... Neuron 109 (14), 2275-2291. e8, 2021 | 89 | 2021 |
| GluR1 controls dendrite growth through its binding partner, SAP97 W Zhou, L Zhang, X Guoxiang, J Mojsilovic-Petrovic, K Takamaya, ... Journal of Neuroscience 28 (41), 10220-10233, 2008 | 83 | 2008 |
| Synaptic dysfunction and altered excitability in C9ORF72 ALS/FTD A Starr, R Sattler Brain research 1693, 98-108, 2018 | 80 | 2018 |
