| The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells PG Longo, L Laurenti, S Gobessi, S Sica, G Leone, DG Efremov Blood, The Journal of the American Society of Hematology 111 (2), 846-855, 2008 | 375 | 2008 |
| MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents M Monte, M Simonatto, LY Peche, DR Bublik, S Gobessi, MA Pierotti, ... Proceedings of the National Academy of Sciences 103 (30), 11160-11165, 2006 | 314 | 2006 |
| Bruton’s tyrosine kinase (BTK) function is important to the development and expansion of chronic lymphocytic leukemia (CLL) JA Woyach, E Bojnik, AS Ruppert, MR Stefanovski, VM Goettl, ... Blood, The Journal of the American Society of Hematology 123 (8), 1207-1213, 2014 | 258 | 2014 |
| Inhibition of constitutive and BCR-induced Syk activation downregulates Mcl-1 and induces apoptosis in chronic lymphocytic leukemia B cells S Gobessi, L Laurenti, PG Longo, L Carsetti, V Berno, S Sica, G Leone, ... Leukemia 23 (4), 686-697, 2009 | 248 | 2009 |
| ZAP-70 enhances B-cell–receptor signaling despite absent or inefficient tyrosine kinase activation in chronic lymphocytic leukemia and lymphoma B cells S Gobessi, L Laurenti, PG Longo, S Sica, G Leone, DG Efremov Blood 109 (5), 2032-2039, 2007 | 230 | 2007 |
| The Akt signaling pathway determines the different proliferative capacity of chronic lymphocytic leukemia B-cells from patients with progressive and stable disease PG Longo, L Laurenti, S Gobessi, A Petlickovski, M Pelosi, P Chiusolo, ... Leukemia 21 (1), 110-120, 2007 | 189 | 2007 |
| Development and validation of a predictive model for death in acquired severe ADAMTS13 deficiency-associated idiopathic thrombotic thrombocytopenic purpura: the French TMA … Y Benhamou, C Assié, PY Boelle, M Buffet, R Grillberger, S Malot, ... Haematologica 97 (8), 1181, 2012 | 144 | 2012 |
| BCR signaling inhibitors differ in their ability to overcome Mcl-1–mediated resistance of CLL B cells to ABT-199 K Bojarczuk, BK Sasi, S Gobessi, I Innocenti, G Pozzato, L Laurenti, ... Blood, The Journal of the American Society of Hematology 127 (25), 3192-3201, 2016 | 129 | 2016 |
| Signaling pathways activated by antigen-receptor engagement in chronic lymphocytic leukemia B-cells DG Efremov, S Gobessi, PG Longo Autoimmunity reviews 7 (2), 102-108, 2007 | 108 | 2007 |
| The miR-17∼ 92 family regulates the response to Toll-like receptor 9 triggering of CLL cells with unmutated IGHV genes R Bomben, S Gobessi, M Dal Bo, S Volinia, D Marconi, E Tissino, ... Leukemia 26 (7), 1584-1593, 2012 | 103 | 2012 |
| Overexpression of the autoimmunity-associated phosphatase PTPN22 promotes survival of antigen-stimulated CLL cells by selectively activating AKT R Negro, S Gobessi, PG Longo, Y He, ZY Zhang, L Laurenti, DG Efremov Blood, The Journal of the American Society of Hematology 119 (26), 6278-6287, 2012 | 95 | 2012 |
| Two types of BCR interactions are positively selected during leukemia development in the Eμ-TCL1 transgenic mouse model of CLL S Iacovelli, E Hug, S Bennardo, M Duehren-von Minden, S Gobessi, ... Blood, The Journal of the American Society of Hematology 125 (10), 1578-1588, 2015 | 63 | 2015 |
| Phosphorylation of the activation loop tyrosines is required for sustained Syk signaling and growth factor-independent B-cell proliferation L Carsetti, L Laurenti, S Gobessi, PG Longo, G Leone, DG Efremov Cellular signalling 21 (7), 1187-1194, 2009 | 59 | 2009 |
| Wiskott-Aldrich syndrome protein–mediated actin dynamics control type-I interferon production in plasmacytoid dendritic cells F Prete, M Catucci, M Labrada, S Gobessi, MC Castiello, E Bonomi, ... Journal of Experimental Medicine 210 (2), 355-374, 2013 | 56 | 2013 |
| Comparison of ZAP-70/Syk mRNA levels with immunoglobulin heavy-chain gene mutation status and disease progression in chronic lymphocytic leukemia L Laurenti, A Petlickovski, C Rumi, S Gobessi, P Piccioni, M Tarnani, ... haematologica 90 (11), 1533-1540, 2005 | 37 | 2005 |
| The proliferative response to CpG-ODN stimulation predicts PFS, TTT and OS in patients with chronic lymphocytic leukemia M Tarnani, L Laurenti, PG Longo, N Piccirillo, S Gobessi, A Mannocci, ... Leukemia research 34 (9), 1189-1194, 2010 | 36 | 2010 |
| Inhibition of thioredoxin-dependent H2O2 removal sensitizes malignant B-cells to pharmacological ascorbate A Graczyk-Jarzynka, A Goral, A Muchowicz, R Zagozdzon, M Winiarska, ... Redox biology 21, 101062, 2019 | 32 | 2019 |
| FOXO1 promotes resistance of non-Hodgkin lymphomas to anti-CD20-based therapy B Pyrzynska, M Dwojak, A Zerrouqi, G Morlino, P Zapala, N Miazek, ... Oncoimmunology 7 (5), e1423183, 2018 | 31 | 2018 |
| The Aurora A and B kinases are up-regulated in bone marrow-derived chronic lymphocytic leukemia cells and represent potential therapeutic targets F de Paula Careta, S Gobessi, RA Panepucci, E Bojnik, FM de Oliveira, ... haematologica 97 (8), 1246, 2012 | 24 | 2012 |
| TLR9 signaling defines distinct prognostic subsets in CLL DG Efremov, R Bomben, S Gobessi, V Gattei Front Biosci 18 (1), 371-386, 2013 | 21 | 2013 |
