| Crystal structure of the lactose operon repressor and its complexes with DNA and inducer M Lewis, G Chang, NC Horton, MA Kercher, HC Pace, MA Schumacher, ... Science 271 (5253), 1247-1254, 1996 | 1029 | 1996 |
| Calculation of the free energy of association for protein complexes N Horton, M Lewis Protein Science 1 (1), 169-181, 1992 | 444 | 1992 |
| Metal ion-mediated substrate-assisted catalysis in type II restriction endonucleases NC Horton, KJ Newberry, JJ Perona Proceedings of the National Academy of Sciences 95 (23), 13489-13494, 1998 | 147 | 1998 |
| The structure of an RNA/DNA hybrid: a substrate of the ribonuclease activity of HIV-1 reverse transcriptase NC Horton, BC Finzel Journal of molecular biology 264 (3), 521-533, 1996 | 145 | 1996 |
| DNA Cleavage by EcoRV Endonuclease: Two Metal Ions in Three Metal Ion Binding Sites NC Horton, JJ Perona Biochemistry 43 (22), 6841-6857, 2004 | 107 | 2004 |
| Structure of Aart, a designed six-finger zinc finger peptide, bound to DNA DJ Segal, JW Crotty, MS Bhakta, CF Barbas III, NC Horton Journal of molecular biology 363 (2), 405-421, 2006 | 104 | 2006 |
| Cation binding to the integrin CD11b I domain and activation model assessment ET Baldwin, RW Sarver, GL Bryant, KA Curry, MB Fairbanks, BC Finzel, ... Structure 6 (7), 923-935, 1998 | 102 | 1998 |
| Structures, functions, and mechanisms of filament forming enzymes: a renaissance of enzyme filamentation CK Park, NC Horton Biophysical reviews 11 (6), 927-994, 2019 | 81 | 2019 |
| Divalent metal dependence of site-specific DNA binding by Eco RV endonuclease AM Martin, NC Horton, S Lusetti, NO Reich, JJ Perona Biochemistry 38 (26), 8430-8439, 1999 | 80 | 1999 |
| Sequence selectivity and degeneracy of a restriction endonuclease mediated by DNA intercalation NC Horton, LF Dorner, JJ Perona nature structural biology 9 (1), 42-47, 2002 | 74 | 2002 |
| Role of protein-induced bending in the specificity of DNA recognition: crystal structure of EcoRV endonuclease complexed with d (AAAGAT)+ d (ATCTT) NC Horton, JJ Perona Journal of molecular biology 277 (4), 779-787, 1998 | 67 | 1998 |
| Making the most of metal ions NC Horton, JJ Perona nature structural biology 8 (4), 290-293, 2001 | 61 | 2001 |
| Crystallographic snapshots along a protein-induced DNA-bending pathway NC Horton, JJ Perona Proceedings of the National Academy of Sciences 97 (11), 5729-5734, 2000 | 59 | 2000 |
| Recognition of flanking DNA sequences by EcoRV endonuclease involves alternative patterns of water-mediated contacts NC Horton, JJ Perona Journal of Biological Chemistry 273 (34), 21721-21729, 1998 | 57 | 1998 |
| Inhibition of EcoRV Endonuclease by Deoxyribo-3‘-S-phosphorothiolates: A High-Resolution X-ray Crystallographic Study NC Horton, BA Connolly, JJ Perona Journal of the American Chemical Society 122 (14), 3314-3324, 2000 | 46 | 2000 |
| The structure of SgrAI bound to DNA; recognition of an 8 base pair target PW Dunten, EJ Little, MT Gregory, VM Manohar, M Dalton, D Hough, ... Nucleic acids research 36 (16), 5405-5416, 2008 | 43 | 2008 |
| Ca2+ Binding in the Active Site of HincII: Implications for the Catalytic Mechanism, C Etzkorn, NC Horton Biochemistry 43 (42), 13256-13270, 2004 | 39 | 2004 |
| Alteration of sequence specificity of the type II restriction endonuclease HincII through an indirect readout mechanism HK Joshi, C Etzkorn, L Chatwell, J Bitinaite, NC Horton Journal of biological chemistry 281 (33), 23852-23869, 2006 | 37 | 2006 |
| Structural analysis of activated SgrAI–DNA oligomers using ion mobility mass spectrometry X Ma, S Shah, M Zhou, CK Park, VH Wysocki, NC Horton Biochemistry 52 (25), 4373-4381, 2013 | 34 | 2013 |
| Escherichia coli lac repressor-lac operator interaction and the influence of allosteric effectors N Horton, M Lewis, P Lu Journal of molecular biology 265 (1), 1-7, 1997 | 32 | 1997 |
John J PeronaProfessor of Environmental Biochemistry, Portland State UniversityVerified email at pdx.edu
